7 research outputs found
Assessment of the impacts of building construction activities on the environment
Activities in building construction industry contribute to air pollution. In this study, gas data from four locations at each three building construction sites in Doha, Qatar were collected and analyzed. Questionnaires were also administered to companies that are involved in building construction projects. The results showed traces of SO2, CO2, CO and NO2 but in amounts below the detrimental limit stipulated by the Ministry of Environment, Qatar. Questionnaire responses revealed that the extraction of raw materials and the energy consumed during construction occur quite often, but strongly implicated dust generated from construction sites and waste disposal, as major factors causing air pollution in the area. It is therefore, recommended that regular monitoring of air should be carried out within building construction sites to aid detection of air contamination. This will serve as a control measure to stimulate catalytic conversion of exhaust, reuse and recycling of waste materials.
Keywords: Air pollution, Building construction activities, Dust, Emissions and Environment
Volatile constituents and biological activities of the leaf and root of Echinacea species from South Africa
Volatile constituents and biological activities of the leaf and root of Echinacea species from South Africa
Volatile constituents and biological activities of the leaf and root of Echinacea species from South Africa
Echinacea is used ethnomedicinally for the treatment of various diseases such as cough, respiratory infections, and bronchitis among other uses in Eastern Cape region of South Africa. This study evaluated the volatile components of the essential oil of the plant, its toxicity, anti-inflammatory and analgesic activities in rodents.
Dried leaf and root of the plant were separately processed by hydrodistillation for 4 h and their essential oils (EOs) were collected. Extracted oils were subjected to GC/GC–MS analysis. The essential oil was further evaluated for acute toxicity, anti-inflammatory and analgesic activities. The toxicity profile of the essential oil was evaluated in mice through the oral route (p.o.), and anti-inflammatory activity was evaluated on the carrageenan-induced edema model in rats at the doses of 100–200 mg/kg, while its analgesic effect was evaluated on the acetic acid-induced writhings model in mice at doses of 100–200 mg/kg.
GC/GC–MS analysis of EOs showed that a number of compounds identified in the leaf and root oils were 25 and 31 respectively. The chemical compositions of the oils varied and the major compounds identified in the oils include germacrene D, naphthalene, caryophyllene oxide, α-phellandrene and α-cadinol. The essential root oil did not cause mortality at the highest dose of 5000 mg/kg; hence, its LD50 was estimated to be ⩾5000 mg/kg, p.o. The anti-inflammatory test results showed that the essential root oil caused significant (p < 0.05–0.01) reduction in edema size compared to the negative control group on the carrageenan-induced edema and the results for the analgesic test showed that the essential root oil caused significant (p < 0.05) reduction in number of writhings at 1000 mg/kg compared to the negative control group.
It is concluded that root and leaf of this Echinacea species contain volatile oils which varied in their yield and chemical compositions. The essential root oil is non-toxic orally and it demonstrated significant anti-inflammatory and analgesic activities in laboratory animals