31 research outputs found
Comparative study of the oxidation reactions of pectic substances, of cellulose and of the structural, units of these substances
Condensation of 2,3-dialdehyde-6-O-tritylcellulose and 2,3-dialdehydecellulose with p-tolylhydrazine and subsequent reduction
Genetic engineering of peptide hormones
Peptide and polypeptide hormones represent an extensive group of biologically active compounds of important significance for medicine and agriculture. In recent years genetic engineering methods have been used to create strains of microorganisms synthesizing eukaryotic proteins, including hormones and their precursors. The first stage of such developments is the isolation of DNA coding the des~red product. We have accomplished the cloning of the cDNA of a number of polypeptide and peptide hormones of the pituitary of man and domestic animals. The model gene of human calcitonin has also been synthesized and cloned. The obtained genes are being used to develop methods for the microbiological synthesis of human and animal-hormones
Comparative study of the oxidation reactions of pectic substances, of cellulose, and of the structural units of these substances
Genetic engineering of peptide hormones : III. Cloning of cDNA of porcine growth hormone and construction of gene for expression of hormone in bacteria
Results are presented of cloning cDNA of procine growth hormone, analysis of its primary structure, and creation of a construction capable of expression of this cDNA in Esqheriahia coti cells. It is shown that in the population of mRNA coding porcine growth hormone, heterogeneity is noted which is manifested not only at the level of the nucleotide sequence, but also is reflected in the amino acid sequence of the mature hormone
Crystal solvates of thermotropic alkylenearomatic copolyesters and poly(m-phenyleneisophthalamide) with N-methylmorpholine-N-oxide
Diagnostic Oligonucleotide Microarray Fingerprinting of Bacillus Isolates
A genome-independent microarray and new statistical techniques were used to genotype Bacillus strains and quantitatively compare DNA fingerprints with the known taxonomy of the genus. A synthetic DNA standard was used to understand process level variability and lead to recommended standard operating procedures for microbial forensics and clinical diagnostics