Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of muscular dystrophy data-0

<p><b>Copyright information:</b></p><p>Taken from "Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of muscular dystrophy data"</p><p>BMC Bioinformatics 2006;7():183-183.</p><p>Published online 3 Apr 2006</p><p>PMCID:PMC1450310.</p><p>Copyright © 2006 Vinciotti et al; licensee BioMed Central Ltd.</p>ral one, especially at increasing levels of noise (bold line, right panel)

Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of muscular dystrophy data-1

<p><b>Copyright information:</b></p><p>Taken from "Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of muscular dystrophy data"</p><p>BMC Bioinformatics 2006;7():183-183.</p><p>Published online 3 Apr 2006</p><p>PMCID:PMC1450310.</p><p>Copyright © 2006 Vinciotti et al; licensee BioMed Central Ltd.</p> test only for genes significant at the 5% confidence level according to the non-temporal test (shaded in grey)

Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of muscular dystrophy data-3

<p><b>Copyright information:</b></p><p>Taken from "Exploiting the full power of temporal gene expression profiling through a new statistical test: Application to the analysis of muscular dystrophy data"</p><p>BMC Bioinformatics 2006;7():183-183.</p><p>Published online 3 Apr 2006</p><p>PMCID:PMC1450310.</p><p>Copyright © 2006 Vinciotti et al; licensee BioMed Central Ltd.</p>her order polynomials), as determined by microarray and qPCR assays, are plotted. The left panel shows the log-ratios with respect to time point 1 estimated from the microarray data; the middle panel shows the fitted second order polynomials; the right panel shows the log-ratios determined by quantitative PCR, as an independent confirmation method for the microarray data. X-axis represents time points. Solid lines represent WT mice; dashed lines MDX mice; dotted lines BSG mice; dashed line interrupted with dots GSG mice