1,414 research outputs found
Ground state energies of quantum dots in high magnetic fields: A new approach
We present a new method for calculating ground state properties of quantum
dots in high magnetic fields. It takes into account the equilibrium positions
of electrons in a Wigner cluster to minimize the interaction energy in the high
field limit. Assuming perfect spin alignment the many-body trial function is a
single Slater determinant of overlapping oscillator functions from the lowest
Landau level centered at and near the classical equilibrium positions. We
obtain an analytic expression for the ground state energy and present numerical
results for up to N=40.Comment: 4 pages, including 2 figures, contribution to the Proceedings of
EP2DS-14, submitted to Physica
Theory of stripe domains in magnetic shape memory alloys
The evolution of multivariant patterns in thin plates of magnetic shape
memory materials with an applied magnetic field was studied theoretically. A
geometrical domain-model is considered composed of straight stripe-like
martensite variants with constant internal magnetization (high anisotropy
limit) and magnetic domain wall orientation fixed by the twin boundaries.
Through integral transforms of the demagnetization energy, the micromagnetic
energy is cast into a form convenient for direct numerical evaluation and
analytical calculations. The equilibrium geometrical parameters of multivariant
patterns with straight and oblique twin boundaries have been derived as
functions of the applied field and the material parameters of a plate. It is
shown that the oblique multivariant states exist only in plates with
thicknesses L larger than a certain critical value L_0. In samples with L < L_0
a magnetic-field-driven transformation occurs directly between single variant
states.Comment: Materials for E-MRS Fall Meeting, Warsaw 2007. Corrected figure
Leptin receptor JAK2/STAT3 signaling modulates expression of Frizzled receptors in articular chondrocytes
SummaryObjectiveDifferentiated articular chondrocytes express a functional bisoform of the leptin receptor (LRb); however, leptin-LRb signaling in these cells is poorly understood. We hypothesized that leptin-LRb signaling in articular chondrocytes functions to modulate canonical Wnt signaling events by altering the expression of Frizzled (FZD) receptors.MethodsHuman chondrocyte cell lines and primary articular chondrocytes were grown in serum containing growth media for 24h, followed by a media change to Dulbecco’s modified Eagle’s medium (DMEM) containing 1% Nutridoma-SP to obtain a serum-deficient environment for 24h before treatment. Treatments included recombinant human leptin (10–100nM), recombinant human IL-6 (0.3–3nM), or recombinant human erythropoietin (Epo) (10mU/ml). Cells were harvested 30min–48h after treatment and whole cell lysates were analyzed using immunoblots or luciferase assays.ResultsTreatment of cells with leptin resulted in activation of Janus kinase 2 (JAK2) and subsequent phosphorylation of specific tyrosine residues on LRb, followed by dose- and time-dependent increases in the expression of Frizzled-1 (FZD1) and Frizzled-7 (FZD7). Leptin-mediated increases in the expression of FZD1 were blocked by pre-treatment with the protein synthesis inhibitor cycloheximide or the JAK2 inhibitor AG490. Experiments using a series of hybrid Epo extracellular domain-leptin intracellular domain receptors (ELR) harboring mutations of specific tyrosine residues in the cytoplasmic tail showed that increases in the expression of FZD1 were dependent on LRb-mediated phosphorylation of STAT3, but not ERK1/2 or STAT5. Leptin pre-treatment of chondrocytes prior to Wnt3a stimulation resulted in an increased magnitude of canonical Wnt signaling.ConclusionThese experiments show that leptin-LRb signaling in articular chondrocytes modulates expression of canonical Wnt signaling receptors and suggests that direct cross-talk between these pathways is important in determining chondrocyte homeostasis
Spin-sensitive Bleaching and Spin-Relaxation in QW's
Spin-sensitive saturation of absorption of infrared radiation has been
investigated in p-type GaAs QWs. It is shown that the absorption saturation of
circularly polarized radiation is mostly controlled by the spin relaxation time
of the holes. The saturation behavior has been investigated for different QW
widths and in dependence on the temperature with the result that the saturation
intensity substantially decreases with narrowing of QWs. Spin relaxation times
were experimentally obtained by making use of calculated (linear) absorption
coefficients for inter-subband transitions
Spin relaxation times of 2D holes from spin sensitive bleaching of inter-subband absorption
We present spin relaxation times of 2D holes obtained by means of spin
sensitive bleaching of the absorption of infrared radiation in p-type
GaAs/AlGaAs quantum wells (QWs). It is shown that the saturation of
inter-subband absorption of circularly polarized radiation is mainly controlled
by the spin relaxation time of the holes. The saturation behavior has been
determined for different QW widths and in a wide temperature range with the
result that the saturation intensity substantially decreases with narrowing of
the QWs. Spin relaxation times are derived from the measured saturation
intensities by making use of calculated (linear) absorption coefficients for
direct inter-subband transitions. It is shown that spin relaxation is due to
the D'yakonov-Perel' mechanism governed by hole-hole scattering. The problem of
selection rules is addressed.Comment: 14 pages, 5 figure
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