Circular presentation of the <i>mcr-1</i> containing <i>IncX4</i> plasmid in the colistin susceptible <i>E</i>.<i>coli</i>.

<p>In green the <i>mcr-1</i> sequence. In red the IS10R insertion sequence, interrupting the <i>mcr-1</i> gene at position 572. Arrows indicate open reading frames (ORFs), dark blue ORFs with annotation, light blue ORFs without annotation (hypothetical protein). Numbers indicate nucleotide positions.</p

Antibiotic phenotype with the corresponding molecular resistance of cultured <i>mcr-1</i> containing <i>E</i>.<i>coli</i>.

<p>Antibiotic phenotype with the corresponding molecular resistance of cultured <i>mcr-1</i> containing <i>E</i>.<i>coli</i>.</p

Primers and probe used to screen for the presence of <i>mcr</i>-genes.

<p>Primers and probe used to screen for the presence of <i>mcr</i>-genes.</p