Patterns of expression levels of cytokines, chemokines and growth and differentiation factors, assessed in the previous study of Beumer <i>et al</i>. and in the current study [7].

<p>Patterns of expression levels of cytokines, chemokines and growth and differentiation factors, assessed in the previous study of Beumer <i>et al</i>. and in the current study [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153892#pone.0153892.ref007" target="_blank">7</a>].</p

Comparison of growth and differentiation factors between healthy controls and subjects.

<p>Comparison of growth and differentiation factors between healthy controls and subjects.</p

Serum levels of growth and differentiation factors in healthy controls (C), Seroconverting (SC) and Non-Seroconverting (NSC) family members.

<p>Serum levels of growth and differentiation factors in healthy controls (C), Seroconverting (SC) and Non-Seroconverting (NSC) family members.</p

Selenium status and association with bone mineral density.

<p>Selenium status and association with bone mineral density.</p

Associations between selenium status and thyroid function tests.

<p>Associations between selenium status and thyroid function tests.</p

Ft4 measures when TSH falls within the normal range.

<p>FT4 measures when TSH falls within the normal range (0.45–4.5 mU/L); 85% of abnormal fT4 measures are within 2 pmol/l (dashed lines) of the reference range (11.2 to 20.8 pmol/L, solid lines). Abbreviations: Free Thyroxine (fT4) Thyroid-Stimulating Hormone (TSH).</p

Participant characteristics.

<p>Participant characteristics.</p

Number of individuals with low, normal, and high TSH and FT4.

<p>Number of individuals with low, normal, and high TSH and FT4.</p

Baseline characteristics.

<p>Baseline characteristics.</p

Heat map showing the Cq values of all detectable MiRNAs (n = 135) in the different thyroid states.

<p>Clustering did not group the samples according to thyroid state.</p