Synthesis and Spectroscopic Studies of Glucose-Derived Carbopeptoids

Present research focuses оп the hybrid building blocks that сап Ье used to synthesize carbapeptoids with trans-orientated functional groups

β-Turns Forming Carbopeptoids

We present the synthesis and spectroscopic studies of the furanose-based amide- and triazole-linked carbopeptoids

Structural Hybrids: Combining the Best of Sugars, Peptides, and Heterocycles

Over time, 1,2,3-triazoles as well as sugar amino acids were addressed to mimic both the amide bonds of peptides and the foldamer abilities of the latter. Acetonide protected pento- and hexofuranoses are stereochemically defined molecular scaffolds that impose certain rigidity to the oligomeric structures made from them. Connection with an amide linkage provides open sites for the formation of intramolecular hydrogen bonds when incorporated in the larger molecules Herein we present the synthesis of furanose-based amide- and triazole-linked saccharopeptides I and II

Saccharopeptides and Their Triazole Isosteres

We present the syntheses of furanose-based triazole- and amide-linked saccharopeptides

Synthesis of Triazole-Linked Oligosaccharides

Apskatīta ar triazola starpcukura saiti saistītu oligosaharīdu sintēze. Darbā izmantota 1,3-dipolārā ciklopievienošanās reakcij

Copper and Ruthenium Catalyzed "Clicking" of Carbohydrate Derivatives

Šajās tēzēs apskatīta vara un rutēnija katalizēta oligosaharīda-triazolu konjugātu sintēz

Tetrahydrofuran Amino Acids of the Past Decade

Review: syntheses of THF α-, β-, γ-, δ- and longer chain amino acids; 78 refs

Peptidosaccharides and Their Triazole Isosteres

Synthesis of amide-linked and triazole-linked oligosaccharides is discusse

Tetrahydrofuran Amino Acids of the Past Decade

Sugar amino acids (SAA) belong to the class of hybrid molecules which contain both the structural pattern of carbohydrates and functional groups characteristic for amino acids. Numerous applications of SAA in medicinal chemistry and in the synthesis of foldamers have initiated various synthetic approaches towards these structurally interesting and functional group – rich molecules. This review covers the past decade’s achievements in the synthesis of one distinct subclass of SAA: tetrahydrofuran amino acids (furanoid sugar amino acids)