1 research outputs found
Graphene Oxide and Lipid Membranes: Interactions and Nanocomposite Structures
We have investigated the interaction between graphene
oxide and
lipid membranes, using both supported lipid membranes and supported
liposomes. Also, the reverse situation, where a surface coated with
graphene oxide was exposed to liposomes in solution, was studied.
We discovered graphene oxide-induced rupture of preadsorbed liposomes
and the formation of a nanocomposite, bio-nonbio multilayer structure,
consisting of alternating graphene oxide monolayers and lipid membranes.
The assembly process was monitored in real time by two complementary
surface analytical techniques (the quartz crystal microbalance with
dissipation monitoring technique (QCM-D) and dual polarization interferometry
(DPI)), and the formed structures were imaged with atomic force microscopy
(AFM). From a basic science point of view, the results point toward
the importance of electrostatic interactions between graphene oxide
and lipid headgroups. Implications from a more practical point of
view concern structure–activity relationship for biological
health/safety aspects of graphene oxide and the potential of the nanocomposite,
multilayer structure as scaffolds for advanced biomolecular functions
and sensing applications