105 research outputs found
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Negotiating rights: the Guatemalan peace process
The signing of peace agreements in 1996 ended 36 years of civil war between the Guatemalan government and the Marxist rebel army, Guatemalan National Revolutionary Unit. The peace process went beyond an arrangement between armed groups, allowing regional and civic actors to advance their concerns on issues of social justice, political power-sharing and the rule of law. Accord issue 2 analyses the degree to which deep-seated historical grievances about unfair land distribution, the marginalisation of indigenous people, tight controls on political organisation and unacceptable state violence became marginalised during the process, and the remaining challenges in consolidating the peace agreement. Written by local and international authors, the publication also includes a timeline of the peace process, the full peace accord texts and profiles of the main people and institutions involved
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Culture and Rights: Anthropological Perspectives
Do people everywhere have the same, or even compatible, ideas about multiculturalism, indigenous rights or women's rights? The authors of this book move beyond the traditional terms of the universalism-versus-cultural relativism debate. Through detailed case studies from around the world (Hawai'i, France, Thailand, Botswana, Greece, Nepal and Canada) they explore the concrete effects of rights talk and rights institutions on people's lives
Proteomic Insight into Functional Changes of Proteorhodopsin-Containing Bacterial Species <i>Psychroflexus torquis</i> under Different Illumination and Salinity Levels
The extremely psychrophilic proteorhodopsin-containing
bacterial
species <i>Psychroflexus torquis</i> is considered to be
a model sea-ice microorganism, which has adapted to an epiphytic lifestyle.
So far, not much is known about proteorhodopsin-based phototrophy
and associated life strategies of sea ice bacteria, although it has
been previously shown that <i>P. torquis</i> can gain growth
advantage from light using a proteorhodopsin proton pump, the activity
of which is influenced by environmental salinity. The comprehensive
quantitative proteomic study performed here indicated that <i>P. torquis</i> responds to changing salinity and illumination
conditions. Proteins in the electron-transfer chain were down-regulated
at a suboptimal salinity level, TonB-dependent transporters increased
in abundance under supra-optimal salinity and decreased under suboptimal
salinity. In addition, several anaplerotic CO<sub>2</sub> fixation
proteins and three putative light sensing proteins that contain PAS
and GAF domains became more abundant under illumination. Furthermore,
central metabolic pathways (TCA and glycolysis) were also induced
by both salinity stress and illumination. The data suggest that <i>P. torquis</i> responded to changes in both light energy and
salinity to modulate membrane and central metabolic proteins that
are involved in energy production as well as nutrient uptake and gliding
motility processes that would be especially advantageous during the
polar summer ice algal bloom
Proteomic Insight into Functional Changes of Proteorhodopsin-Containing Bacterial Species <i>Psychroflexus torquis</i> under Different Illumination and Salinity Levels
The extremely psychrophilic proteorhodopsin-containing
bacterial
species <i>Psychroflexus torquis</i> is considered to be
a model sea-ice microorganism, which has adapted to an epiphytic lifestyle.
So far, not much is known about proteorhodopsin-based phototrophy
and associated life strategies of sea ice bacteria, although it has
been previously shown that <i>P. torquis</i> can gain growth
advantage from light using a proteorhodopsin proton pump, the activity
of which is influenced by environmental salinity. The comprehensive
quantitative proteomic study performed here indicated that <i>P. torquis</i> responds to changing salinity and illumination
conditions. Proteins in the electron-transfer chain were down-regulated
at a suboptimal salinity level, TonB-dependent transporters increased
in abundance under supra-optimal salinity and decreased under suboptimal
salinity. In addition, several anaplerotic CO<sub>2</sub> fixation
proteins and three putative light sensing proteins that contain PAS
and GAF domains became more abundant under illumination. Furthermore,
central metabolic pathways (TCA and glycolysis) were also induced
by both salinity stress and illumination. The data suggest that <i>P. torquis</i> responded to changes in both light energy and
salinity to modulate membrane and central metabolic proteins that
are involved in energy production as well as nutrient uptake and gliding
motility processes that would be especially advantageous during the
polar summer ice algal bloom
Additional file 3: of Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature
Total number of quantifiable proteins. Proteins identified on the basis of two or more unique matching peptide sequences and presence in at least six of the nine biological replicates in either treatment group (XLSX 160 kb
Additional file 2: of Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature
MaxQuant output files of the complete protein-level mass spectrometry. A total of nine biological replicates (fish) per temperature treatment were analysed. (XLSX 2354 kb
Additional file 4: of Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature
Full list of canonical pathways as determined by temperature-regulated proteins and predicted by IPA analysis. The significance of the association between the data set and the pathway is based on the p-value, which determines the probability that the association between the data set genes and the pathway is explained only by chance, and on the ratio value, representing the number of genes from the data found in each pathway over the total number of genes in that pathway. (XLSX 56 kb
Additional file 5: of Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature
Components of the top five toxicity pathways as determined by temperature-regulated proteins and predicted by IPA analysis. Exp fold change and Exp p-value correspond with the fold change value and the adjusted p-value (using Benjamini Hochberg correction), respectively, reported in Additional file 3. (XLSX 52 kb
Additional file 1: of Liver proteome response of pre-harvest Atlantic salmon following exposure to elevated temperature
MaxQuant output files of the complete peptide-level mass spectrometry. A total of nine biological replicates (fish) per temperature treatment were analysed. (XLSX 5578 kb
Differences in protein abundance between FO and TOFX livers.
<p>Volcano plot displaying differences of the pairwise comparison. Proteins found to be significantly (adjusted p < 0.1; p < 0.05) different between treatments are plotted in red and described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0161513#pone.0161513.t007" target="_blank">Table 7</a>. Larger black circles represent those proteins significantly different at a lower stringent threshold (adjusted p < 0.3; p < 0.05).</p
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