X-Ray Spectral Variability of PKS 2005-489 During the Spectacular November 1998 Flare

We report on monitoring of the BL Lac object PKS 2005-489 by the Rossi X-ray Timing Explorer (RXTE) in October-December 1998. During these months, the source underwent a spectacular flare; at its peak on November 10, its 2-10 keV flux was $3.33 \times 10^{-10} {\rm ~erg ~cm^{-2} ~s^{-1}}$, over 30 times brighter than in quiescence. During the rising phase, the X-ray spectrum of PKS 2005-489 hardened considerably, reaching $\alpha = 1.32~ (F_\nu \propto \nu^{-\alpha})$ near maximum. During the declining phase, the X-ray spectrum steepened rapidly, reaching $\alpha = 1.82$, then became somewhat harder towards the end of December ($\alpha \sim 1.6$). While such behavior has been seen before, the simplicity, magnitude and duration of this flare allowed us to study it in great detail. We argue that this flare was caused by either the injection of particles into the jet or {\it in situ} particle acceleration, and that the spectral steepening which followed the flare maximum was the result of synchrotron cooling. Contrary to other recently observed blazar flares (e.g., Mkn 501, 3C 279, PKS 2155-304), our results do not imply a major shift in the location of the synchrotron peak during this flare.Comment: ApJ Letters in press, 6 pages, 2 figures Corrected reference

"Dark Matter" in Accretion Disks

Using Spitzer Space Telescope photometric observations of the eclipsing, interacting binary WZ Sge, we have discovered that the accretion disk is far more complex than previously believed. Our 4.5 and 8 micron time series observations reveal that the well known gaseous accretion disk is surrounded by an asymmetric disk of dusty material with a radius approximately 15 times larger than the gaseous disk. This dust ring contains only a small amount of mass and is completely invisible at optical and near-IR wavelengths, hence consisting of "dark matter". We have produced a model dust ring using 1 micron spherical particles with a density of 3 g/cm$^3$ and with a temperature profile ranging from 700-1500K. Our discovery about the accretion disk structure and the presence of a larger, outer dust ring have great relevance for accretion disks in general, including those in other interacting binary systems, pre-main sequence stars, and active galaxies.Comment: 34 pages, 8 figures (3 in color). Accepted to Ap

Entry in the ADHD drugs market: Welfare impact of generics and me-toos

Recent decades have seen a growth in treatments for attention deficit hyperactivity disorder (ADHD) including many branded and generic drugs. In the early 2000's, new drug entry dramatically altered market shares. We estimate a demand system for ADHD drugs and assess the welfare impact of new drugs. We find that entry induced large welfare gains by reducing prices of substitute drugs, and by providing alternative delivery mechanisms for existing molecules. Our results suggest that the success of follow-on patented drugs may come from unanticipated innovations like delivery mechanisms, a factor ignored by proposals to retard new follow-on drug approvals

Variable Star Candidates in an ACS Field of M31

A search for variable stars is performed using two epochs of Hubble Space Telescope (HST) Advanced Camera for Surveys (ACS) imaging data for a 9.28 square arcminute portion of M31. This data set reveals 254 sources that vary by at least 4-sigma between epochs. The positions and 2-epoch B-band (equivalent) photometry of these sources are presented. The photometry suggests that this catalog includes most of the RR Lyrae population of this portion of M31.Comment: 22 pages, 3 tables, 5 figures, accepted for publication in A

BL Lac X-ray Spectra: simpler than we thought

We report results from {\it XMM-Newton} observations of thirteen X-ray bright BL Lacertae objects, selected from the {\it Einstein} Slew Survey sample. The spectra are generally well fit by power-law models, with four objects having hard ($\alpha<1; F_\nu \propto \nu^{-\alpha}$) spectra that indicates synchrotron peaks at $>5$ keV. None of our spectra show line features, indicating that soft X-ray absorption ``notches'' must be rare amongst BL Lacs, rather than common or ubiquitous as had previously been asserted. We find significant curvature in most of the spectra. This curvature is almost certainly intrinsic, as it appears nearly constant from 0.5 to 6 keV, an observation which is inconsistent with the small columns seen in these sources.Comment: 4 pages, 1 figure; to be published in proceedings of the Cozumel meeting on "Multiwavelength Surveys for AGN", Cozumel 200