13 research outputs found
The in vitro addition of methotrexate and/or methylprednisolone determines peripheral reduction in Th17 and expansion of conventional Treg and of IL-10 producing Th17 lymphocytes in patients with early rheumatoid arthritis
No full textIL-27 triggers IL-10 production in Th17 cells via a c-Maf/RORÎłt/Blimp-1 signal to promote the progression of endometriosis
No full textEvolution of prostate MRI: from multiparametric standard to less-is-better and different-is better strategies
No full textVirulence Megaplasmids in Bacillus anthracis and Their Relatives in the Bacillus cereus Group
No full textG-Protein-Coupled Estrogen Receptor Agonist Suppresses Airway Inflammation in a Mouse Model of Asthma through IL-10
No full textGenome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation
No full textSensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer’s disease
No full textThe unfolded protein response in the immune cell development : putting the caretaker in the driving seat
No full textThe endoplasmic reticulum (ER) is the primary site for the folding of proteins destined for the membranous compartment and the extracellular space. This elaborate function is coordinated by the unfolded protein response (UPR), a stress-activated cellular program that governs proteostasis. In multicellular organisms, cells have adopted specialized functions, which required functional adaptations of the ER and its UPR. Recently, it has become clear that in immune cells, the UPR has acquired functions that stretch far beyond its original scope. In this review, we will discuss the role of the UPR in the immune system and highlight the plasticity of this signaling cascade throughout immune cell development
The Genome of a Bacillus Isolate Causing Anthrax in Chimpanzees Combines Chromosomal Properties of B. cereus with B. anthracis Virulence Plasmids
No full text
