Squib-operated disconnect

Disconnect device is described, which consists of stud with enlarged end held in collet locked by pins, which are held in place by piston. When squib is fired, trapped combustion products force piston to release pins

The evolution of carrying capacity in constrained and expanding tumour cell populations

Cancer cells are known to modify their micro-environment such that it can sustain a larger population, or, in ecological terms, they construct a niche which increases the carrying capacity of the population. It has however been argued that niche construction, which benefits all cells in the tumour, would be selected against since cheaters could reap the benefits without paying the cost. We have investigated the impact of niche specificity on tumour evolution using an individual based model of breast tumour growth, in which the carrying capacity of each cell consists of two components: an intrinsic, subclone-specific part and a contribution from all neighbouring cells. Analysis of the model shows that the ability of a mutant to invade a resident population depends strongly on the specificity. When specificity is low selection is mostly on growth rate, while high specificity shifts selection towards increased carrying capacity. Further, we show that the long-term evolution of the system can be predicted using adaptive dynamics. By comparing the results from a spatially structured vs.\ well-mixed population we show that spatial structure restores selection for carrying capacity even at zero specificity, which a poses solution to the niche construction dilemma. Lastly, we show that an expanding population exhibits spatially variable selection pressure, where cells at the leading edge exhibit higher growth rate and lower carrying capacity than those at the centre of the tumour.Comment: Major revisions compared to previous version. The paper is now aimed at tumour modelling. We now start out with an agent-based model for which we derive a mean-field ODE-model. The ODE-model is further analysed using the theory of adaptive dynamic

Disconnect unit

A squib-actuated disconnect is characterized by an expandable collet axially extended from a first tension member for receiving in locking engagement a protuberance axially extended from a second tension member. A gas-driven retainer of an annular configuration is also locked in for supporting the collet in locking engagement with the protuberance. The protuberance is axially displaced in response to a firing of an associated squib for thus accommodating a disengagement of the protuberance and the collet

Initial-Boundary Value Problem for Stimulated Raman Scattering Model: Solvability of Whitham Type System of Equations Arising in Long-Time Asymptotic Analysis

An initial-boundary value problem for a model of stimulated Raman scattering was considered in [Moskovchenko E.A., Kotlyarov V.P., J. Phys. A: Math. Theor. 43 (2010), 055205, 31 pages]. The authors showed that in the long-time range $t\to+\infty$ the $x>0$, $t>0$ quarter plane is divided into 3 regions with qualitatively different asymptotic behavior of the solution: a region of a finite amplitude plane wave, a modulated elliptic wave region and a vanishing dispersive wave region. The asymptotics in the modulated elliptic region was studied under an implicit assumption of the solvability of the corresponding Whitham type equations. Here we establish the existence of these parameters, and thus justify the results by Moskovchenko and Kotlyarov

Some findings on the applications of ERTS and Skylab imagery for metropolitan land use analysis

The author has identified the following significant results. Work undertaken on a three-sensor land use data evaluation for a portion of the Phoenix area is reported. Analyses between land use data generated from 1970 high altitude photography and that detectable from ERTS and Skylab, especially in terms of changes in land use indicate that ERTS and Skylab imagery can be used effectively to detect and identify areas of post-1970 land use change, especially those documenting urban expansion at the rural-urban fringe. Significant preliminary findings on the utility of ERTS and Skylab data for metropolitan land use analysis, substantiated by evaluation with 1970 and 1972 ground control land use data are reported

Urban and regional land use analysis: CARETS and Census Cities experiment package

The author has identified the following significant results. Areas of post 1970 and 1972 land use changes were identified solely from the Skylab imagery from comparisons with 1970 land use maps. Most land use changes identified involved transition from agriculture to single family residential land use. The second most prominent changes identified from the Skylab imagery were areas presently under construction. Post 1970 changes from Skylab were compared with the 1972 changes noted from the high altitude photographs. A good correlation existed between the change polygons mapped from Skylab and those mapped from the 1972 high altitude aerial photos. In addition, there were a number of instances where additional built-up land use not noted in the 1972 aerial photo as being developed were identified on the Skylab imagery. While these cases have not been documented by field observation, by correlating these areas with the appearance of similar land use areas whose identity has been determined, we can safely say that we have been able to map further occurrences of land use change beyond existing high altitude photo coverage from the Skylab imagery. It was concluded that Skylab data can be used to detect areas of land use change within an urban setting