2 research outputs found
Synthesis and anticancer property of one Ce(III) compound based on 5-(2-pyrazinyl)tetrazole-2-acetic acid
No full text<p>Mononuclear [Ce(pztza)<sub>2</sub>(H<sub>2</sub>O)<sub>6</sub>](pztza)·H<sub>2</sub>O (<b>1</b>) (pztza = 5-(2-pyrazinyl)tetrazole-2-acetato) has been prepared and characterized by IR, elemental analysis and single-crystal X-ray diffraction. PEG<sub>-5000</sub> (poly(ethyleneglycol<sub>-5000</sub>)) coated [Ce(pztza)<sub>2</sub>(H<sub>2</sub>O)<sub>6</sub>](pztza)·H<sub>2</sub>O nanoparticles (NPs) can disperse into distilled water. <i>In vitro</i> study on Hela cells shows that Hpztza is nontoxic while [Ce(pztza)<sub>2</sub>(H<sub>2</sub>O)<sub>6</sub>](pztza)·H<sub>2</sub>O NPs show high toxicity with half-maximal inhibitory concentration (IC<sub>50</sub>) of 17 μg/mL (1.93 × 10<sup>−5</sup> M). In addition, such NPs can inhibit the migration of Hela cells effectively.</p
pH-dependent synthesis of a cadmium coordination compound from a compound based on Hpytz ligand [Hpytz = 5-(4-pyridyl)tetrazole]
No full text<div><p>Reactions of CdSO<sub>4</sub>·6H<sub>2</sub>O and Hpytz [Hpytz = 5-(4-pyridyl)tetrazole] under high pH values produced a known compound, [Cd(pytz)<sub>2</sub>(H<sub>2</sub>O)<sub>4</sub>]·2H<sub>2</sub>O (<b>1</b>), which can be used to prepare [Cd(Hpytz)(SO<sub>4</sub>)(H<sub>2</sub>O)<sub>2</sub>] (<b>2</b>) by adjusting the pH to a lower level using sulfuric acid under hydrothermal conditions. These compounds were characterized by elemental analysis, IR spectroscopy, and single-crystal diffraction. X-ray analysis reveals that <b>1</b> features a mononuclear structure, while <b>2</b> affords a 1-D polymeric chain structure. Compound <b>1</b> displays a 2-D network, while <b>2</b> shows a 3-D network by hydrogen bonding interactions. Furthermore, the luminescent properties were investigated at room temperature in the solid state.</p></div
