An automated system for lung nodule detection in low-dose computed tomography

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical Computed Tomography (CT) images was developed in the framework of the MAGIC-5 Italian project. One of the main goals of this project is to build a distributed database of lung CT scans in order to enable automated image analysis through a data and cpu GRID infrastructure. The basic modules of our lung-CAD system, a dot-enhancement filter for nodule candidate selection and a neural classifier for false-positive finding reduction, are described. The system was designed and tested for both internal and sub-pleural nodules. The results obtained on the collected database of low-dose thin-slice CT scans are shown in terms of free response receiver operating characteristic (FROC) curves and discussed.Comment: 9 pages, 9 figures; Proceedings of the SPIE Medical Imaging Conference, 17-22 February 2007, San Diego, California, USA, Vol. 6514, 65143

Computer-aided detection of pulmonary nodules in low-dose CT

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector helical CT images with 1.25 mm slice thickness is being developed in the framework of the INFN-supported MAGIC-5 Italian project. The basic modules of our lung-CAD system, a dot enhancement filter for nodule candidate selection and a voxel-based neural classifier for false-positive finding reduction, are described. Preliminary results obtained on the so-far collected database of lung CT scans are discussed.Comment: 3 pages, 4 figures; Proceedings of the CompIMAGE - International Symposium on Computational Modelling of Objects Represented in Images: Fundamentals, Methods and Applications, 20-21 Oct. 2006, Coimbra, Portuga

A scalable system for microcalcification cluster automated detection in a distributed mammographic database

A computer-aided detection (CADe) system for microcalcification cluster identification in mammograms has been developed in the framework of the EU-founded MammoGrid project. The CADe software is mainly based on wavelet transforms and artificial neural networks. It is able to identify microcalcifications in different datasets of mammograms (i.e. acquired with different machines and settings, digitized with different pitch and bit depth or direct digital ones). The CADe can be remotely run from GRID-connected acquisition and annotation stations, supporting clinicians from geographically distant locations in the interpretation of mammographic data. We report and discuss the system performances on different datasets of mammograms and the status of the GRID-enabled CADe analysis.Comment: 6 pages, 4 figures; Proceedings of the IEEE NNS and MIC Conference, October 23-29, 2005, Puerto Ric

Proper Motions of H2O Masers in the Water Fountain Source IRAS 19190+1102

We report on the results of two epochs of Very Long Baseline Array (VLBA) observations of the 22 GHz water masers toward IRAS 19190+1102. The water maser emission from this object shows two main arc-shaped formations perpendicular to their NE-SW separation axis. The arcs are separated by ~280 mas in position, and are expanding outwards at an angular rate of 2.35 mas/yr. We detect maser emission at velocities between -53.3 km/s to +78.0 km/s and there is a distinct velocity pattern where the NE masers are blueshifted and the SW masers are redshifted. The outflow has a three-dimensional outflow velocity of 99.8 km/s and a dynamical age of about 59 yr. A group of blueshifted masers not located along the arcs shows a change in velocity of more than 35 km/s between epochs, and may be indicative of the formation of a new lobe. These observations show that IRAS 19190+1102 is a member of the class of "water fountain"' pre-planetary nebulae displaying bipolar structureComment: Accepted for publication in ApJ, corrected typo

Spatially resolved spectroscopy of Cassiopeia A with MECS on board B⃗eppo{\vec Beppo}SAX

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UV (IUE) spectra of the central stars of high latitude planetary nebulae Hb7 and Sp3

We present an analysis of the UV (IUE) spectra of the central stars of Hb7 and Sp3. Comparison with the IUE spectrum of the standard star HD 93205 leads to a spectral classification of O3V for these stars, with an effective temperature of 50,000 K. From the P-Cygni profiles of CIV (1550 A), we derive stellar wind velocities and mass loss rates of -1317 km/s +/- 300 km/s and 2.9X10^{-8} solar mass yr^{-1} and -1603 km/s +/- 400 km/s and 7X10^{-9} solar mass yr^{-1} for Hb7 and Sp3 respectively. From all the available data, we reconstruct the spectral energy distribution of Hb7 and Sp3.Comment: 4 pages, 3 figures, latex, accepted for publication in Astronomy & Astrophysic

Comparison of Magnetic Field Structures on Different Scales in and around the Filamentary Dark Cloud GF 9

New visible polarization data combined with existing IR and FIR polarization data are used to study how the magnetic field threading the filamentary molecular cloud GF 9 connects to larger structures in its general environment. We find that when both visible and NIR polarization data are plotted as a function of extinction, there is no evidence for a plateau or a saturation effect in the polarization at Av ~ 1.3 as seen in dark clouds in Taurus. This lack of saturation effect suggests that even in the denser parts of GF 9 we are still probing the magnetic field. The visible polarization is smooth and has a well-defined orientation. The IR data are also well defined but with a different direction, and the FIR data in the core region are well defined and with yet another direction, but are randomly distributed in the filament region. On the scale of a few times the mean radial dimension of the molecular cloud, it is as if the magnetic field were `blind' to the spatial distribution of the filaments while on smaller scales within the cloud, in the core region near the IRAS point source PSC 20503+6006, polarimetry shows a rotation of the magnetic field lines in these denser phases. Hence, in spite of the fact that the spatial resolution is not the same in the visible/NIR and in the FIR data, all the data put together indicate that the field direction changes with the spatial scale. Finally, the Chandrasekhar and Fermi method is used to evaluate the magnetic field strength, indicating that the core region is approximately magnetically critical. A global interpretation of the results is that in the core region an original poloidal field could have been twisted by a rotating elongated (core+envelope) structure. There is no evidence for turbulence and ambipolar diffusion does not seem to be effective at the present time.Comment: 33 pages, 6 tables, 8 figures, Accepted by Ap

Automated detection of lung nodules in low-dose computed tomography

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector computed-tomography (CT) images has been developed in the framework of the MAGIC-5 Italian project. One of the main goals of this project is to build a distributed database of lung CT scans in order to enable automated image analysis through a data and cpu GRID infrastructure. The basic modules of our lung-CAD system, consisting in a 3D dot-enhancement filter for nodule detection and a neural classifier for false-positive finding reduction, are described. The system was designed and tested for both internal and sub-pleural nodules. The database used in this study consists of 17 low-dose CT scans reconstructed with thin slice thickness (~300 slices/scan). The preliminary results are shown in terms of the FROC analysis reporting a good sensitivity (85% range) for both internal and sub-pleural nodules at an acceptable level of false positive findings (1-9 FP/scan); the sensitivity value remains very high (75% range) even at 1-6 FP/scanComment: 4 pages, 2 figures: Proceedings of the Computer Assisted Radiology and Surgery, 21th International Congress and Exhibition, Berlin, Volume 2, Supplement 1, June 2007, pp 357-35