455 research outputs found

    Examining the Applicability of the Concepts of Apology, Forgiveness, and Reconciliation to Multi-Stakeholder, Collaborative Problem-Solving Processes

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    In 2004, Meridian Institute, an organization with expertise in designing, facilitating, and mediating collaborative problem-solving processes, was asked to assess the feasibility of forming collaborative, community-based-watershed groups in northern New Mexico to develop plans to address water-quality problems and--if determined to be feasible--to facilitate the formation of those groups and plans. Early in the assessment process it became clear that the historical context was critically important and was one of the factors that had to be addressed. Here, Miles explores the applicability of apology, forgiveness, and reconciliation to a collaborative group process that can be examined through the example of community-based watershed groups working to identify mutually acceptable water-quality-improvement strategies

    Views of Inclusive Education from the Perspectives of Pre-service and Mentor Teachers

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    The trend of inclusive education in the U.S.A., and across the globe, is expanding. Consequently, teacher preparation for inclusive practices is thus a necessary consideration for teacher educators worldwide. An important role in shaping pre-service teacher dispositions comes from school experiences and interactions with mentor teachers. It is through this relationship that pre-service teachers formulate their own attitudes, beliefs and skills around inclusive practices. This paper reports the findings from a set of surveys containing both closedand open-ended responses related to inclusive education from both pre-service (student) and mentor teachers. Analysis of the open-ended responses revealed definitions of inclusive education focused on student deficits, and barriers to implementation of inclusive practices that focused on deficits in the capacity of the environment. Four themes emerged when participants defined inclusion. Both groups of educators further described their perceived barriers to implementing inclusive education for students with disabilities, as well as the concerns they have heard others express as organized by five themes. Implications for teacher preparation, including challenging of deficit-based assumptions, are discussed

    Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus

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    The tumor suppressor protein p53 is known to be transported to the nucleus along microtubular tracks by cytoplasmic dynein. However, the connection between p53 and the dynein motor protein complex has not been established. Here, we show that hsp90.binding immunophilins link p53.hsp90 complexes to dynein and that prevention of that linkage in vivo inhibits the nuclear movement of p53. First, we show that p53.hsp90 heterocomplexes from DLD-1 human colon cancer cells contain an immunophilin (FKBP52, CyP-40, or PP5) as well as dynein. p53.hsp90.immunophilin.dynein complexes can be formed by incubating immunopurified p53 with rabbit reticulocyte lysate, and we show by peptide competition that the immunophilins link via their tetratricopeptide repeat domains to p53-bound hsp90 and by means of their PPIase domains to the dynein complex. The linkage of immunophilins to the dynein motor is indirect by means of the dynamitin component of the dynein-associated dynactin complex, and we show that purified FKBP52 binds directly by means of its PPIase domain to purified dynamitin. By using a temperature-sensitive mutant of p53 where cytoplasmic-nuclear movement occurs by shift to permissive temperature, we show that p53 movement is impeded when p53 binding to hsp90 is inhibited by the hsp90 inhibitor radicicol. Also, nuclear movement of p53 is inhibited when immunophilin binding to dynein is competed for by expression of a PPIase domain fragment in the same manner as when dynein linkage to cargo is dissociated by expression of dynamitin. This is the first demonstration of the linkage between an hsp90-chaperoned transcription factor and the system for its retrograde movement to the nucleus both in vitro and in vivo.Fil: Galigniana, Mario Daniel. University of Michigan; Estados Unidos. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaFil: Harrell, Jennifer M.. University of Michigan; Estados UnidosFil: O´Hagen, Heather M.. University of Michigan; Estados UnidosFil: Ljungman, Mats. University of Michigan; Estados UnidosFil: Pratt, William B.. University of Michigan; Estados Unido

    Housing the urban poor--a case for space-sharing in Ahmedabad, India

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    Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 1991.Includes bibliographical references (leaves 122-126).by Jennifer D. Pratt.M.C.P

    The Role of the Opioid Crisis in Elder Abuse

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    As the opioid crisis has deepened over the past twenty years, its effect on individuals and families, including older adults, has grown. To find out how the opioid crisis might be impacting elder abuse, neglect, and exploitation in Maine, we conducted a mixed methods analysis of 2015-2018 Maine Adult Protective Services (APS) investigations to determine: 1) Did opioid-related investigations increase over time? 2) Do investigations involving opioid misuse or abuse differ from investigations that don’t involve opioids? 3) What themes or features of cases involving opioid misuse or abuse by clients and/or perpetrators emerge from the data? Key Findings: The annual number of opioid-related investigations increased 2015-2018, but the rate of increase was parallel to the general increase of elder abuse investigations over the time period. Opioid-related investigations ranged between 2.5-2.9% of all elder abuse investigations over the time period. Clients in opioid-related investigations tended to be younger than clients in non-drug-related investigations. Forty percent of clients in Opioid-related investigations were 60-69 years old compared to twenty-three percent of clients in Non-drug-related investigations. Opioid-related investigations were more likely to have three or more allegations and include an allegation of exploitation compared to Non-drug-related investigations. Common themes in the opioid-related investigations included: Clients with opioid prescriptions also exhibited signs of substance use disorder (SUD) or opioid use disorder (OUD); clients with opioid prescriptions had difficulties managing their prescriptions, including taking too much or too little, or needing to hide their medication to keep them away from family members or others.; clients with opioid prescriptions encountered barriers to obtaining the medications such as not being able to have their pharmacy deliver them, having to travel to appointments for pill counts, or being denied access to an opioid medication due to the behavior of a family member. In exploitation investigations, there were instances of the perpetrator stealing the client\u27s money or property to purchase drugs elsewhere as well as instances of stealing the client\u27s money and the client\u27s opioid prescription. Client use of opioids can put them at risk of exploitation through impaired physical and cognitive ability

    A compilation of digitized satellite imagery of the Gulf Stream (1982, 1983, and 1985)

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    Ninety plots of digitized temperature boundaries from infared satellite images of the Gulf Stream along with corresponding image snapshots were compiled to determine stream width propagation speed. The satellite images are from the years 1982, 1983, and 1985 and are often of consecutive days. In this report, these images and digitized plots are presented.Funding was provided by the Office of Naval Research through contract Number N00014-87-K-0007, and by the National Science Foundation under grant Numbers OCE 87-00601 and OCE 85-10828

    Creative Compensation: How Arts Organizations Can Recruit and Retain the Best People Using Quality of Life Incentives

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    There is a gap between what the for-profit sector pays and what the nonprofit sector pays for similar positions and experience. In order for nonprofit arts organizations to attract and retain the best employees, they must to consider what other incentives to include in their compensation packages. This thesis examines what fringe benefits, both common and unique, are currently being offered to employees in lieu of additional salary in both the for-profit and not-for-profit sectors, then presents the results of a survey of 328 arts administrators in the Greater Philadelphia area which shows what each of these benefits would be worth to them monetarily. This thesis then makes recommendations as to the average range of worth specific incentives may hold for a potential or current employee, the purpose of which is to aid nonprofit arts organizations in creating competitive compensation packages designed to attract and retain the best staff.M.S., Arts Administration -- Drexel University, 201

    Personal Experiences With Long Term Care Services and Supports

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    This report captures, in a direct way, the first hand experiences of older and disabled consumers of long term care services and supports. In addition, it includes the collective experiences of eight Maine communities regarding the long term care service delivery system in our state
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