3 research outputs found
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Novel Low-Cost Smartphone Enabled Contaminant Detection Device
Recently, ambulance acquired infections are of increasing concern as the scope of procedures that EMS personnel perform has increased. Cleaning assessment increases cleaning efficacy reducing acquired infections â however due to high initial cost of devices, ambulances cannot afford this assessment step. To address this, the team has created a low cost alternative to current ATP detection systems. The ATP in contaminants, combined with Luciferase, emits a light with intensity proportional to ATP concentration, indicating contamination. The teamâs novel design uses a photodiode along with a Smartphone app in order to quantify light emission and provide fast, user friendly results. The light intensity this design can detect is 0.2 to 50 mW/cm2 at 520nm, a viable range for ATP detection
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Ambulatory Resuscitative Care and Surgery
Ambulance transport times can be a matter of life and death. Overcrowding problems in emergency rooms add to the time patients must wait before receiving care. RECAS aims to create a pre-hospital vehicle in which patient diagnosis and both minor and time-sensitive surgeries are performed on-scene, preceding transport to a hospital. Information was gathered from case studies on survival rates and response times relating to trauma injuries; interviewing EMTs and hospital personnel; and researching medical equipment and devices, personnel, and procedures to treat patients with time-sensitive injuries. Analysis of this data resulted in the design of a new, mobile critical care ambulance that intends to improve the overall quality of care in the pre-hospital environment, saving lives overall
Genomic reconstruction of the SARS-CoV-2 epidemic in England
AbstractThe evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus leads to new variants that warrant timely epidemiological characterization. Here we use the dense genomic surveillance data generated by the COVID-19 Genomics UK Consortium to reconstruct the dynamics of 71 different lineages in each of 315 English local authorities between September 2020 and June 2021. This analysis reveals a series of subepidemics that peaked in early autumn 2020, followed by a jump in transmissibility of the B.1.1.7/Alpha lineage. The Alpha variant grew when other lineages declined during the second national lockdown and regionally tiered restrictions between November and December 2020. A third more stringent national lockdown suppressed the Alpha variant and eliminated nearly all other lineages in early 2021. Yet a series of variants (most of which contained the spike E484K mutation) defied these trends and persisted at moderately increasing proportions. However, by accounting for sustained introductions, we found that the transmissibility of these variants is unlikely to have exceeded the transmissibility of the Alpha variant. Finally, B.1.617.2/Delta was repeatedly introduced in England and grew rapidly in early summer 2021, constituting approximately 98% of sampled SARS-CoV-2 genomes on 26 June 2021.</jats:p