Managing hyperlipidaemia in patients with COVID-19 and during its pandemic: An expert panel position statement from HEART UK

The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes Coronavirus Disease 2019 (COVID-19) has resulted in a pandemic. SARS-CoV-2 is highly contagious and its severity highly variable. The fatality rate is unpredictable but is amplified by several factors including advancing age, atherosclerotic cardiovascular disease, diabetes mellitus, hypertension and obesity. A large proportion of patients with these conditions are treated with lipid lowering medication and questions regarding the safety of continuing lipid-lowering medication in patients infected with COVID-19 have arisen. Some have suggested they may exacerbate their condition. It is important to consider known interactions with lipid-lowering agents and with specific therapies for COVID-19. This statement aims to collate current evidence surrounding the safety of lipid-lowering medications in patients who have COVID-19. We offer a consensus view based on current knowledge and we rated the strength and level of evidence for these recommendations. Pubmed, Google scholar and Web of Science were searched extensively for articles using search terms: SARS-CoV-2, COVID-19, coronavirus, Lipids, Statin, Fibrates, Ezetimibe, PCSK9 monoclonal antibodies, nicotinic acid, bile acid sequestrants, nutraceuticals, red yeast rice, Omega-3-Fatty acids, Lomitapide, hypercholesterolaemia, dyslipidaemia and Volanesorsen. There is no evidence currently that lipid lowering therapy is unsafe in patients with COVID-19 infection. Lipid-lowering therapy should not be interrupted because of the pandemic or in patients at increased risk of COVID-19 infection. In patients with confirmed COVID-19, care should be taken to avoid drug interactions, between lipid-lowering medications and drugs that may be used to treat COVID-19, especially in patients with abnormalities in liver function tests

The Digital Adaptive Control of a Linear Process Modulated by Random Noise

93 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1962.U of I OnlyRestricted to the U of I community idenfinitely during batch ingest of legacy ETD

Engineering: Cornell Quarterly, Vol.23, No.3 (Spring 1989): Computer Graphics in the Education of Engineers

IN THIS ISSUE: Punch Cards to Color Graphics: The Story of Educational Computing at Cornell /2 (Christopher Pottle, the associate dean for computing at the College of Engineering, reviews the rapid development of instructional computing in the undergraduate curricula, and considers its future development.) ... The Computer-Aided Design Instructional Facility: 1980's Radical Experiment Is Today's Solid Success /6 (Kate Mink, the coordinator of instructional computing, discusses a unique facility at the College of Engineering and the plans for further integration of computer-aided design in undergraduate engineering education.) ... SOCRATES??puter-Age Teacher at Cornell's Engineering College: A Unique Program Offers Educational Graphic Software to Other Engineering Schools /20 (Sari Lynn Goldbaum, an applications programmer who works with Project SOCRATES, discusses the innovative program and its benefits.) ... Register /30 ... Faculty Publications /3

Laboratory Workstations in Electrical Engineering

Computers, configured for data acquisition and control, have been used in undergraduate laboratories at Cornell University's School of Electrical Engineering since the early 1970s. The introduction of personal computers in the introductory laboratory course sequence (Fall/Spring of Junior Year) has permitted a dramatic expansion of this practice. Previously, computers were used in group experiments with limited student interaction. Now each student has access to an IBM Personal Computer with analog and digital input/output capabilities as well as the usual electronic instruments. Instructionally, data acquisition is emphasized during the fall semester. BASIC commands and programs are implemented to exercise analog-to-digital and digital-to-analog converters. A "canned" program collects samples (to 20,000 samples/sec) and performs spectral analysis (FFT) on periodic waveforms including the exciting current of a transformer. Three experiments in the spring semester demonstrate the capabilities of the laboratory workstation. (1) The spectral analysis program is used to demonstrate aliasing and examine distortion in a class-B amplifier. (2) A computer controlled experiment determines the impurity profiles of p-n junctions by sampling the capacitance as a function of reverse bias. (3) Filter circuits are tested automatically for transient and frequency response using the computer. Numerical integration, FFT, and inverse FFT are used to simulate circuit responses.Cornell Universit

Engineering: Cornell Quarterly, Vol.08, No.3 (Autumn 1973): The Science of Information

IN THIS ISSUE: The Nature of Information: The Province of Computer Science in the University Today /2 (Not machines but knowledge about information itself is the main concern of computer science departments. The functions of Cornell's department and the professional interests of university computer scientists are discussed by Professor Richard W. Conway.) ... Approaches to the New Library /8 (A world authority on information storage and retrieval, Gerard Salton, describes how automatic techniques can be used in the development of new systems to meet the "library crisis." Professor Salton is chairman of Cornell's Department of Computer Science.) ... The Computer as Laboratory Instrument /17 (From the Apollo mission to the undergraduate laboratory, computers are essential components of experimental equipment. This increasingly important aspect of information science is discussed by Christopher Pottle, associate professor of electrical engineering.) ... Commentary /25 (How the computer is affecting society and its members and what can or should be done about it is considered by Visiting Assistant Professor David Lewis, a Cornell Ph.D. in computer science who is directing an interdisciplinary Cornell seminar, The Computerized Society.) ... Register /28 (New members of the College of Engineering faculty are introduced.) ... Faculty Publications /3

“A priceless book to have out here”: soldiers reading Shakespeare in the first world war

The links between the 1916 Shakespeare tercentenary and the global conflict with which it coincided have been the subject of increasing scholarly attention. Recent work has examined the cultural, political, and military contexts of commemoration events and shown how Shakespeare as cultural symbol was mobilized for war. No systematic work has yet been done, however, on the most basic level of Shakespeare's cultural mobilization: the individual act of reading Shakespeare in the context of wartime. Utilising the methodologies of the new “history of reading”, this article examines the place of Shakespeare's texts in the reading lives of British and Commonwealth soldiers. Drawing upon contemporary letters and diaries, it demonstrates that there are several distinct types of Shakespearean reading practice recoverable from the archives. “Compliant” readers strove to recover conventionally patriotic messages from Shakespeare's texts. “Nostalgic” readers used Shakespeare as a form of escapism or a way of asserting a civilian identity separate from military service. Direct evidence for the reading habits of ordinary soldiers is more difficult to recover from the archives than those of officers. Nevertheless, scattered references to Shakespearean texts in the diaries and correspondence of ordinary-ranking soldiers show that Shakespeare could also function as a symbol of cultural literacy for working-class autodidacts at war