Metaborreflexo muscular inspiratório em indivíduos hipertensos

Indivíduos com hipertensão arterial sistêmica podem apresentar o metaborreflexo muscular inspiratório exacerbado comparado a indivíduos normotensos. No primeiro estudo, comparamos as respostas hemodinâmicas e respiratórias da ativação deste reflexo entre hipertensos e normotensos. Em uma amostra de conveniência, 31 participantes realizaram o protocolo de indução do metaborreflexo muscular inspiratório com carga e o protocolo controle. No protocolo de indução com carga houve maior aumento da pressão arterial média e redução do fluxo sanguíneo da perna para os hipertensos em relação aos normotensos. Conclui-se que o metaborreflexo muscular inspiratório pode estar exacerbado nos indivíduos hipertensos. O segundo estudo, protocolo de ensaio clínico randomizado duplo cego, foi publicado e tem como objetivo testar a eficácia do treinamento muscular inspiratório sobre a redução dos níveis pressóricos de hipertensos.Individuals with systemic arterial hypertension may present exacerbated inspiratory muscle metaboreflex compared to normotensive individuals. In the first study, we compared the hemodynamic and respiratory responses of the activation of this reflex between hypertensive and normotensive individuals. In a convenience sample, 31 participants performed the induction protocol of inspiratory muscle metaborreflex with load and the control protocol. In the protocol of induction with load there was a greater increase in mean arterial pressure and reduction of blood flow from the leg to hypertensive patients in relation to the normotensive ones. It is concluded that inspiratory muscle metaboreflex may be exacerbated in hypertensive subjects. The second study, a randomized double-blind clinical trial protocol, was published and aims to test the effectiveness of inspiratory muscle training on the reduction of blood pressure levels in hypertensive patients

Metaborreflexo muscular inspiratório em indivíduos hipertensos

Indivíduos com hipertensão arterial sistêmica podem apresentar o metaborreflexo muscular inspiratório exacerbado comparado a indivíduos normotensos. No primeiro estudo, comparamos as respostas hemodinâmicas e respiratórias da ativação deste reflexo entre hipertensos e normotensos. Em uma amostra de conveniência, 31 participantes realizaram o protocolo de indução do metaborreflexo muscular inspiratório com carga e o protocolo controle. No protocolo de indução com carga houve maior aumento da pressão arterial média e redução do fluxo sanguíneo da perna para os hipertensos em relação aos normotensos. Conclui-se que o metaborreflexo muscular inspiratório pode estar exacerbado nos indivíduos hipertensos. O segundo estudo, protocolo de ensaio clínico randomizado duplo cego, foi publicado e tem como objetivo testar a eficácia do treinamento muscular inspiratório sobre a redução dos níveis pressóricos de hipertensos.Individuals with systemic arterial hypertension may present exacerbated inspiratory muscle metaboreflex compared to normotensive individuals. In the first study, we compared the hemodynamic and respiratory responses of the activation of this reflex between hypertensive and normotensive individuals. In a convenience sample, 31 participants performed the induction protocol of inspiratory muscle metaborreflex with load and the control protocol. In the protocol of induction with load there was a greater increase in mean arterial pressure and reduction of blood flow from the leg to hypertensive patients in relation to the normotensive ones. It is concluded that inspiratory muscle metaboreflex may be exacerbated in hypertensive subjects. The second study, a randomized double-blind clinical trial protocol, was published and aims to test the effectiveness of inspiratory muscle training on the reduction of blood pressure levels in hypertensive patients

Functional capacity, pulmonary and respiratory muscle strength in individuals undergoing hemodialysis

Introduction: Individuals with chronic kidney disease (CKD) undergoing hemodialysis (HD) present low cardiorespiratory fitness and functional capacity. Metabolic changes, due to the disease, can result in a variety of pathophysiological conditions that favor the development of respiratory muscle weakness. However, very little is known about the performance of the respiratory muscles and the influence of HD on them. Aim: To evaluate and correlate pulmonary function, functional capacity and respiratory muscle strength in patients with CKD undergoing HD. Methods: Cross-sectional study comprising 23 patients with CKD, that met the following inclusion criteria: patients of both genders, who perform HD three times a week for a minimum period of three months. Respiratory muscle strength was evaluated using a respiratory pressure meter, lung function through spirometry and functional capacity through the 6-minute walk test (6MWT) before the HD session. Results: All patients were male and mean age was 50.2 ± 15.8 years. The median duration of HD was 3 (1.5 to 6.0) years. The mean values obtained in comparison to those predicted were MIP% 36.0 ± 13.6, MEP% 49.5 ± 15.8, FVC% 93.8 ± 21.1, FEV1% 93.7 ± 21.1, FVC/VEF1% 104.1 ± 10.3, and 6MWT% 66.33 ± 20.53. A statistically significant positive correlation was observed between the 6MWT and MIP (r = .63, p =.001) and MEP (r = .67, p elt; .001), between the MIP and MEP (r =.79, p elt; .001) and between the FEV1 and FVC (r = .91, p elt; .001). Conclusion: Patients with CKD undergoing HD present changes in respiratory muscle strength, with the predicted values decreasing for age and gender, as well as the distance covered in the 6MWT, although, with normal spirometric values. Functional capacity was dependent on respiratory muscle strength, as well as the values of MIP and MEP, and the values of FVC and FEV1

Functional capacity, pulmonary and respiratory muscle strength in individuals undergoing hemodialysis

Abstract Introduction: Individuals with chronic kidney disease (CKD) undergoing hemodialysis (HD) present low cardiorespiratory fitness and functional capacity. Metabolic changes, due to the disease, can result in a variety of pathophysiological conditions that favor the development of respiratory muscle weakness. However, very little is known about the performance of the respiratory muscles and the influence of HD on them. Aim: To evaluate and correlate pulmonary function, functional capacity and respiratory muscle strength in patients with CKD undergoing HD. Methods: Cross-sectional study comprising 23 patients with CKD, that met the following inclusion criteria: patients of both genders, who perform HD three times a week for a minimum period of three months. Respiratory muscle strength was evaluated using a respiratory pressure meter, lung function through spirometry and functional capacity through the 6-minute walk test (6MWT) before the HD session. Results: All patients were male and mean age was 50.2 ± 15.8 years. The median duration of HD was 3 (1.5 to 6.0) years. The mean values obtained in comparison to those predicted were MIP% 36.0 ± 13.6, MEP% 49.5 ± 15.8, FVC% 93.8 ± 21.1, FEV1% 93.7 ± 21.1, FVC/VEF1% 104.1 ± 10.3, and 6MWT% 66.33 ± 20.53. A statistically significant positive correlation was observed between the 6MWT and MIP (r = .63, p =.001) and MEP (r = .67, p < .001), between the MIP and MEP (r =.79, p < .001) and between the FEV1 and FVC (r = .91, p < .001). Conclusion: Patients with CKD undergoing HD present changes in respiratory muscle strength, with the predicted values decreasing for age and gender, as well as the distance covered in the 6MWT, although, with normal spirometric values. Functional capacity was dependent on respiratory muscle strength, as well as the values of MIP and MEP, and the values of FVC and FEV1