The lower urinary tract symptoms in patients after transurethral resection of benign prostatic hyperplasia

We performed a retrospective analysis of medical records and prospective evaluation of TUR in the long term, which was carried out in patients with BPH. The real picture of the possibilities of examination and treatment of patients with LUTS together with urological can be accessed from portal UroWeb.ru. A survey of urologists in the public domain was conducted. Such an indication, as the ineffectiveness of conservative therapy has been established for young patients with a small volume of the prostat

ROLE OF ANGIOGENIC FACTORS FOR TRANSPLACENTAL TRANSFER OF THE MEASLES ANTIBODIES

Angiogenesis factors (VEGF, Ang-1, TGF-β) influence production, development and functioning of vascular endothelium that are part of the placental barrier structure and are involved into transplacental transfer of different substances. The aim of this study was to study the relationship between VEGF, Ang-1, and TGF-β concentrations, and the levels of transplacental IgG-antibodies to the measles virus in cord blood of children born to mothers with placental insufficiency. Patients and methods: venous blood was taken from 32 women with uncomplicated pregnancies, and 34 samples from pregnant women with placental insufficiency, as well as umbilical blood of their newborns, the level of IgG-antibodies to measles and the concentration of some angiogenic factors (VEGF, Ang-1, TGF-β) examined by ELISA techniques. The following results were obtained: in a cord blood of infants seronegative for the measles virus, born to women with placental insufficiency, showed uniformly low VEGF levels, decreased Ang-1 concentration (1.6) and increased TGF-β concentration (2.7) as compared to seropositive newborns. In a similar group of children from mothers with physiological pregnancy, the level of these factors did not differ from those in newborns with protective antibodies to measles. Conclusion: in physiological pregnancy, transplacental transmission of IgG-antibodies to the measles virus is directly dependent on the presence of specific antibodies in a woman; in case of placental insufficiency, an imbalance in the system of angiogenic factors may promote disturbances of transmission mechanisms for IgG measles-specific antibodies from mother to the fetus

The lower urinary tract symptoms in patients after transurethral resection of benign prostatic hyperplasia

We performed a retrospective analysis of medical records and prospective evaluation of TUR in the long term, which was carried out in patients with BPH. The real picture of the possibilities of examination and treatment of patients with LUTS together with urological can be accessed from portal UroWeb.ru. A survey of urologists in the public domain was conducted. Such an indication, as the ineffectiveness of conservative therapy has been established for young patients with a small volume of the prostat

The lower urinary tract symptoms in patients after transurethral resection of benign prostatic hyperplasia

We performed a retrospective analysis of medical records and prospective evaluation of TUR in the long term, which was carried out in patients with BPH. The real picture of the possibilities of examination and treatment of patients with LUTS together with urological can be accessed from portal UroWeb.ru. A survey of urologists in the public domain was conducted. Such an indication, as the ineffectiveness of conservative therapy has been established for young patients with a small volume of the prostat

Immunoprotection against toxic biomarkers is retained during Parkinson's disease progression

The aim was to ascertain any possible linkage between humoral immune responses to principal biomarkers (α-synuclein monomers, its toxic oligomers or fibrils, dopamine and S100B) and cellular immunity in Parkinson's disease development. There were elevated autoantibody titers to α-synuclein monomers, oligomers plus fibrils in 72%, 56%, and 17% of Parkinsonian patients respectively with a 5-year disease duration. Additionally, there were increased titers to dopamine and S100B (96% and 89%) in the 5-year patient group. All of these values subsided in 10-year sufferers. Furthermore, CD3+, CD4+, CD8+ T-lymphocyte and B-lymphocyte subsets declined in the patient cohort during Parkinsonism indicating disease associated reductions in these lymphocyte subsets