Strong spatial dispersion in wire media in the very large wavelength limit

It is found that there exist composite media that exhibit strong spatial dispersion even in the very large wavelength limit. This follows from the study of lattices of ideally conducting parallel thin wires (wire media). In fact, our analysis reveals that the description of this medium by means of a local dispersive uniaxial dielectric tensor is not complete, leading to unphysical results for the propagation of electromagnetic waves at any frequencies. Since non--local constitutive relations have been usually considered in the past as a second order approximation, meaningful in the short wavelength limit, the aforementioned result presents a relevant theoretical interest. In addition, since such wire media have been recently used as a constituent of some discrete artificial media (or metamaterials), the reported results open the question of the relevance of the spatial dispersion in the characterization of these artificial media.Comment: MiKTex, 4 pages with 2 figures, submitted to PR

Methionine gamma lyase from clostridium sporogenes increases the anticancer efficacy of doxorubicin on A549 cancer cells in vitro and human cancer xenografts

The anticancer efficacy of methionine γ-lyase (MGL) from Clostridium sporogenes (C. sporogenes) is described. MGL was active against cancer cells in vitro and in vivo. Doxorubicin (DOX) and MGL were more effective on A549 human lung-cancer growth inhibition than either agent alone in vitro and in vivo. © Springer Science+Business Media, LLC, part of Springer Nature 2019

Methionine gamma lyase from Clostridium sporogenes increases the anticancer effect of doxorubicin in A549 cells and human cancer xenografts

Summary: The anti-cancer efficacy of methionine γ-lyase (MGL) from Clostridium sporogenes (C. sporogenes) is described. MGL was active against cancer models in vitro and in vivo. The calculated EC50 values for MGL were 4.4 U/ml for A549, 7.5 U/ml for SK-BR3, 2.4 U/ml for SKOV3, and 0.4 U/ml for MCF7 cells. The combination of doxorubicin (DOX) and MGL was more effective for A549 human lung cancer growth inhibition than either agent alone in vitro and in vivo. MGL reduced the EC50 of doxorubicin from 35.9 μg/mL to 0.01–0.265 μg/mL. The growth inhibitory effect of DOX + MGL on A549 xenografts in vivo was reflective of the results obtained in vitro. The inhibition rate of tumor growth in the combined arm was 57%, significantly higher than that in the doxorubicin (p = 0.033)-alone arm. © 2018 Springer Science+Business Media, LLC, part of Springer Natur

Methionine gamma lyase from Clostridium sporogenes increases the anticancer effect of doxorubicin in A549 cells and human cancer xenografts

Summary: The anti-cancer efficacy of methionine γ-lyase (MGL) from Clostridium sporogenes (C. sporogenes) is described. MGL was active against cancer models in vitro and in vivo. The calculated EC50 values for MGL were 4.4 U/ml for A549, 7.5 U/ml for SK-BR3, 2.4 U/ml for SKOV3, and 0.4 U/ml for MCF7 cells. The combination of doxorubicin (DOX) and MGL was more effective for A549 human lung cancer growth inhibition than either agent alone in vitro and in vivo. MGL reduced the EC50 of doxorubicin from 35.9 μg/mL to 0.01–0.265 μg/mL. The growth inhibitory effect of DOX + MGL on A549 xenografts in vivo was reflective of the results obtained in vitro. The inhibition rate of tumor growth in the combined arm was 57%, significantly higher than that in the doxorubicin (p = 0.033)-alone arm. © 2018 Springer Science+Business Media, LLC, part of Springer Natur

Fission of heavy and superheavy nuclei at low excitation energies

This paper studies comprehensive research through qualitative interviews conducted in Malaysia with SME heads and students about their representations of Information and Communication Technology

Клинические рекомендации по семейной гиперхолестеринемии

These guidelines represent all current aspects of etiology diagnosis, and treatment of the clinical and statistical group of familial hypercholesterolemia in both adults and children in accordance with the requirements of the Ministry of Health of Russia.Данные клинические рекомендации представляют все современные аспекты этиологии, диагностики, лечения семейной гиперхолестеринемии как у взрослых, так и у детей. Рекомендации подготовлены для размещения в соответствующем рубрикаторе клинических рекомендаций Минздрава России в сети Интернет по адресу http://cr.rosmincylrav.ml

Shell effects in fusion-fission of heavy and superheavy nuclei

The process of fusion-fission of heavy and superheavy nuclei (SHE) with Z = 82-122 formed in the reactions with 48Ca and 58Fe ions at energies near and below the Coulomb barrier has been studied. The experiments were carried out at the U-400 accelerator of the Flerov Laboratory of Nuclear Reactions (JINR) and at the XTU Tandem accelerator of the National Laboratory of Legnaro (LNL) using the time-of-flight spectrometer of fission fragments CORSET and the neutron multi-detector DEMON. As a result of the experiments, mass and energy distributions (MED) of fission fragments, fission, quasi-fission and evaporation residues cross sections, multiplicities of neutrons and γ quanta and their dependence on the mechanism of formation and decay of compound systems have been studied.SCOPUS: cp.jinfo:eu-repo/semantics/publishe