53 research outputs found
Community Pharmacy Practice in Italy during the COVID-19 (SARS-CoV-2) Pandemic: Regulatory Changes and a Cross-Sectional Analysis of Seroprevalence
I metodi contraccettivi: le conoscenze dei giovani e il ruolo del farmacista in qualità di counsellor
Development of Standard Operating Protocols for the Optimization of Cannabis-Based Formulations for Medical Purposes
La gestione dell’aderenza alla terapia del paziente anziano politrattato nelle farmacie di comunità
Cannabis-Based Oral Formulations for Medical Purposes: Preparation, Quality and Stability
Current legislation in Italy provides that medical Cannabis may be administered orally or by inhalation. One of the fundamental criteria for the administration of oral formulations is that they deliver a known consistent quantity of the active ingredients to ensure uniform therapies leading to the optimisation of the risks/benefits. In 2018, our group developed an improved Cannabis oil extraction technique. The objective of the present work was to carry out a stability study for the oil extracts obtained by this method. Furthermore, in order to facilitate the consumption of the prescribed medical Cannabis therapy by patients, a standard procedure was defined for the preparation of a single-dose preparation for oral use (hard capsules) containing the oil extract; thereafter, the quality and stability were evaluated. The hard capsules loaded with the oil extract were analysed and found to be uniform in content. The encapsulation process did not alter the quantity of the active molecule present in the oil. The stability tests yielded excellent results. Since the capsule dosage form is easily transported and administered, has pleasant organoleptic properties and is stable at room temperature for extended periods of time, this would facilitate the adherence to therapy by patients in treatment
The importance of a multidisciplinary care: community pharmacies as a hub to support oncologic patients with cutaneous reactions due to treatments
Monitoring adherence to pharmacological therapy and follow-up examinations among patients with type 2 diabetes in community pharmacies. Results from an experience in Italy
Supernova 2010ev: A reddened high velocity gradient type Ia supernova
Aims. We present and study the spectroscopic and photometric evolution of the type Ia supernova (SN Ia) 2010ev.
Methods. We obtain and analyze multiband optical light curves and optical/near-infrared spectroscopy at low and medium resolution spanning -7 days to +300 days from the B-band maximum.
Results. A photometric analysis shows that SN 2010ev is a SN Ia of normal brightness with a light-curve shape of Δm15(B) = 1.12 ± 0.02 and a stretch s = 0.94 ± 0.01 suffering significant reddening. From photometric and spectroscopic analysis, we deduce a color excess of E(B - V) = 0.25 ± 0.05 and a reddening law of Rv = 1.54 ± 0.65. Spectroscopically, SN 2010ev belongs to the broad-line SN Ia group, showing stronger than average Si II λ6355 absorption features.We also find that SN 2010ev is a high velocity gradient SN with ͘vSi = 164 ± 7 km s-1 d-1. The photometric and spectral comparison with other supernovae shows that SN 2010ev has similar colors and velocities to SN 2002bo and SN 2002dj. The analysis of the nebular spectra indicates that the [Fe II] λ7155 and [Ni II] λ7378 lines are redshifted, as expected for a high velocity gradient supernova. All these common intrinsic and extrinsic properties of the high velocity gradient (HVG) group are different from the low velocity gradient (LVG) normal SN Ia population and suggest significant variety in SN Ia explosions.Facultad de Ciencias Astronómicas y GeofÃsicasInstituto de AstrofÃsica de La Plat
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