Multivariate adjusted overall survival rate by quartile of resting heart-rate.

<p>The Paris Prospective Study I.</p

Baseline characteristics of the 6101 men according to causes of mortality.

<p>Continuous data are given as mean (standard deviation)</p><p>Tobacco consumption is the average consumption (grams per day) in the five years preceding the study.</p><p>Physical activity applies to subjects who performed more than one hour of regular activity per week.</p><p>The Paris Prospective Study I.</p

Age and tobacco adjusted relative risks of death according to quartiles of heart-rate parameters.

<p>ΔHRexercise: difference between heart-rate at peak exercise and resting heart-rate</p><p>ΔHRrecovery: difference between heart-rate at peak exercise and after 1 min recovery</p><p>ΔHR5year: difference between resting heart-rate recorded at year 5 and at baseline</p>§<p>The analysis is restricted to 5139 subjects, see methods</p><p>Relative risk that was associated with a heart-rate measurement is given for the second, third and fourth quartile, taken the first quartile as reference. Relative risks were estimated with the Cox proportional-hazard model. CI denotes confidence interval.</p><p>Symbols of p-values for trend test: ***: p<0.0001; **: p<0.01</p><p>The Paris Prospective Study I.</p

Multivariate adjusted cancer free survival rate by quartile of heart-rate increase during exercise.

<p>The Paris Prospective Study I.</p

Regional plots for the association of SNPs with MI in the region of <i>QKI</i>.

<p>Regional plots for the association of SNPs with MI in the region of <i>QKI</i>.</p

Study design for identification and validation of SNPs associated with MI and CHD.

<p>Study design for identification and validation of SNPs associated with MI and CHD.</p

Association of the known SNPs for coronary artery disease with incident MI and CHD in Stage I.

<p>Association of the known SNPs for coronary artery disease with incident MI and CHD in Stage I.</p

Association of the known SNPs for coronary artery disease with mortality after MI.

<p>Association of the known SNPs for coronary artery disease with mortality after MI.</p

Description and association of top SNPs with incident MI and CHD in Stage II and their combined results with Stage I.

<p>Description and association of top SNPs with incident MI and CHD in Stage II and their combined results with Stage I.</p