Mapping of innovative governance models to overcome barriers for nature based urban regeneration

The implementation of urban Nature Based Solutions (NBS) projects is deeply determined by the novelty of the concept. Its innovation is both an opportunity and a challenge: as a new concept, it generates uncertainty due to lack of technical and operational preparedness, but it also allows to deploy innovative approaches, new ways to address old problems and more inclusive practices. Nature4Cities project has systematically conceptualized the barriers and drivers on NBS projects implementation by a review of the state of the art. To see how these barriers can be overcome by governance strategies, different urban and environmental governance models have been mapped and characterized to assess their suitability for different NBS projects. Five clusters have been identified where models are grouped according to the involved actors, their position in the spectrum from high to low government involvement and their level of participation. This theorical model has been applied to real cases to check the incidence of the different clusters. Results show that urban and environmental governance is a map where the different models coexist in different degrees regarding some key axes such as level of innovation, polycentric vs. monocentric, involved sectors, level of participation and scale. Collaborative, multisector, polycentric and adaptive governance models address significant number of previously identified cross-domain barriers showing their suitability. The work presented in this paper can be the basis to define new institutional and governance arrangements that will foster multi-stakeholder involvement, citizens' engagement, leveraging both public and private funding of NBS in cities.This work has been developed in Nature4Cities project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 730468. The authors would like to thanks to Nature4Cities partners for the support received

Delayed diagnosis of coeliac disease increases cancer risk

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Low risk of colon cancer in patients with celiac disease

Objective. Celiac disease (CD) has strongly been established as associated with some site-specific gastrointestinal malignancies. On the contrary, according to the few reports available, the risk of colon carcinoma in CD patients has been described similar to that of general population. In this cohort study, we describe the risk of colon carcinoma in a group of Italian celiac patients. Materials and methods. The study population included all CD patients diagnosed at the Collaborating Centers of the Italian Registry of CD between 1st January 1982 and 31st December 2006. Upon diagnosis of CD and upon at every subsequent clinical control, the Collaborating Centers filled in a validated form for each CD patient reporting information about demographic data, possible occurrence of a neoplasm and adherence to a gluten-free diet. Results. Out of 1757 celiac patients enrolled, 6 developed a colon carcinoma during the follow-up period (mean: 18.1 years). The standardized incidence ratio (SIR) resulted 0.29 (95% CI = 0.07-0.45). Stratifying the risk for the dietary gluten intake, the SIR dropped to 0.07 (95% CI = 0.009-0.27) for CD patients with a strict adherence to a gluten-free diet. Conclusion. We confirm the previous finding that there is low risk to develop a colon cancer in celiac patients

Clinical features of chronic C virus hepatitis in patients with celiac disease

[No abstract available