દક્ષિણ ગુજરાતના ઘોડિયા જાતિનાં સંસ્કારગીતોઃ એક અધ્યયન

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Gut microbiota intervention strategies using active components from medicinal herbs to evaluate clinical efficacy of type 2 diabetes – A review

10.1002/ctd2.170Clinical and Translational Discovery3

The Gut-Skin Microbiota Axis and Its Role in Diabetic Wound Healing-A Review Based on Current Literature

10.3390/ijms23042375INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES23

Gut microbiome in acute pancreatitis: A review based on current literature

10.3748/wjg.v27.i30.5019WORLD JOURNAL OF GASTROENTEROLOGY27305019-5036completedcomplete

Gut Microbiota Dysbiosis as a Target for Improved Post-Surgical Outcomes and Improved Patient Care: A Review of Current Literature

10.1097/SHK.0000000000001654SHOCK554441-454complete

Perceived behavioral problems of school aged children in rural Nepal:a qualitative study

BACKGROUND: Studies on child behavioral problems from low and middle income countries are scarce, even more so in Nepal. This paper explores parents’, family members’ and teachers’ perceptions of child behavioral problems, strategies used and recommendations to deal with this problem. METHOD: In this study, 72 free list interviews and 30 Key Informant Interviews (KII) were conducted with community members of Chitwan district in Nepal. RESULT: The result suggest that addictive behavior, not paying attention to studies, getting angry over small issues, fighting back, disobedience, and stealing were the most commonly identified behavioral related problems of children, with these problems seen as interrelated and interdependent. Results indicate that community members view the family, community and school environments as being the causes of child behavioral problems, with serious impacts upon children’s personal growth, family harmony and social cohesion. The strategies reported by parents and teachers to manage child behavioral problems were talking, listening, consoling, advising and physical punishment (used as a last resort). CONCLUSIONS: As perceived by children and other community dwellers, children in rural Nepalese communities have several behavioral related problems. The findings suggest that multi-level community-based interventions targeting peers, parents, teachers and community leaders could be a feasible approach to address the identified problems

Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss

Traumatic brain injury (TBI) is a major source of worldwide morbidity and mortality. Patients suffering from TBI exhibit a higher susceptibility to bone loss and an increased rate of bone fractures; however, the underlying mechanisms remain poorly defined. Herein, we observed significantly lower bone quality and elevated levels of inflammation in bone and bone marrow niche after controlled cortical impact-induced TBI in in vivo CD-1 mice. Further, we identified dysregulated NF-κB signaling, an established mediator of osteoclast differentiation and bone loss, within the bone marrow niche of TBI mice. Ex vivo studies revealed increased osteoclast differentiation in bone marrow-derived cells from TBI mice, as compared to sham injured mice. We also found bone marrow derived extracellular vesicles (EVs) from TBI mice enhanced the colony forming ability and osteoclast differentiation efficacy and activated NF-κB signaling genes in bone marrow-derived cells. Additionally, we showed that miRNA-1224 up-regulated in bone marrow-derived EVs cargo of TBI. Taken together, we provide evidence that TBI-induced inflammatory stress on bone and the bone marrow niche may activate NF-κB leading to accelerated bone loss. Targeted inhibition of these signaling pathways may reverse TBI-induced bone loss and reduce fracture rates

A disruptive ethnography of Tanzanian-Indians

This paper is a disruptive ethnography of Indians in Tanzania (Tanzanian-Indians). It uses narratives of individuals to challenge the popular ethnographic categories within which the individuals are usually subsumed. This paper analyses three critical questions concerning Category, Homeland and Community. Is the category Mhindi (‘Indian’ in Kiswahili) exhaustive as a cultural identity? What is the relationship of Tanzanian-Indians to their ‘homeland’ India? Does a community-based approach map on to the realities of everyday lives of Tanzanian-Indians? The focus will be on Zanzibar and Dar es Salaam. Both these neighbouring places have significant Indian presence and through ethnographic research using conversations, semi-structured interviews and the self-presentation of individuals through temples, mosques and clubs, we highlight the diversity of experience that lies behind the specific identity category of Mhindi