Traumi infantili, intelligenza emotiva e regolazione delle emozioni in un campione di autori di reati sessuali

The aim of the following study is to examine in the Italian context, the prevalence of adverse childhood experience in a sample of detainee sexual offenders, and their correlation with risk of recidivism, emotional intelligence and emotion regulation. The sample is composed by 32 inmates. For the study the following instruments were used: ACE, DERS-16, TMMS and RM2000. The results show high presence of childhood traumas between sex offenders, and a strong correlation between adverse experiences and a higher risk of recidivism, a lower emotional intelligence and more difficulties in the regulation of bad emotions. Clinical consideration about treatment of sex offender are discussed.L’obiettivo del presente studio è quello di analizzare nel contesto italiano, la prevalenza di traumi infantili in un campione di autori di reati sessuali e indagare quale relazione intercorra tra i pregressi traumi infantili, il rischio di recidiva, l’intelligenza emotiva e la regolazione delle emozioni. Il campione è costituito da 32 soggetti detenuti. Per le rilevazioni sono stati usati i seguenti strumenti: ACE, DERS-16, TMMS e RM2000. Le analisi statistiche mostrano una significativa presenza di traumi infantili e evidenziano una forte correlazione tra questi, il rischio di recidiva, l’intelligenza emotiva e la capacità di gestione delle emozioni negative. Infine, sono discusse alcune implicazioni relative al trattamento conseguenti ai risultati ottenuti

Total fundoplication without division of the short gastric vessels: functional evaluation at one year and review of literature

Aim. Gastro-esophageal reflux disease (GERD) has emerged as one of the most common diseases in modern civilization. We investigated functional evaluation after total fundoplication without division of short gastric vessels and review of literature. Methods. From January 2007 to June 2008 43 patients with chronic gastroesophageal reflux underwent laparoscopic Nissen-Rossetti fundoplication, 7 were lost during the follow-up. Patients underwent endoscopy, 24 hours pH-Metry, preoperatively, 6 months and 12 months after surgery. Articles were sourced from PubMed and Medline, using the MeSH terms "gastroesophageal reflux disease" and "laparoscopic surgery" and "fundoplication technique". Selection of articles were based on peer review, journal, relevance and English language. Results. Endoscopic findings revealed complete healing of esophagitis in all patients. Barrett esophagus was still present. Six patients reported persistence of symptoms but postoperative pH-metry and endoscopy showed the absence of reflux; two patients (5.5%) were still on PPI therapy at 12 months. Seven patients (19.4%) reported dysphagia for solid for at least three months. Re-admission for dysphagia was required for two (5.5%) and one patient underwent to endoscopic dilatation. At six and 12 months no dysphagia was reported. During the follow-up no gas-bloat syndrome was referred. The Johnsson and DeMeester's score reduction from six months to 12 months was statistically significant. Randomized and non-randomized studies seem to point out in a precise way that a division of short gastric vessels is unnecessary to perform a "short and floppy" placation. Conclusion. Nissen-Rossetti fundoplication is safe and effective for treatment of GERD, with minimal post-operative side effects

Partial or Total Fundoplication (With or Without Division of the Short Gastric Vessels): Which is The Best Laparoscopic Choice in GERD Surgical Treatment?

Background: Gastroesophageal reflux disease (GERD) has emerged as one of the most common diseases in the modern civilization. The immense success of laparoscopic surgery as an effective treatment of GERD has established the minimally invasive surgery as the gold standard for this condition with lower morbidity and mortality, shorter hospital stay, faster recovery, and reduced postoperative pain. Methods: Articles were sourced from PubMed and Medline, using the MeSH terms "gastroesophageal reflux disease" and "laparoscopic surgery" and "fundoplication technique." The selection of articles was based on peer review, journal, relevance, and English language. Results and Conclusions: There are some controversies with regard to the technique. First, whether total or partial fundoplication is the more appropriate treatment for GERD; second, if a total fundoplication (360 degrees) is performed, what is the effect of fundic mobilization and the division of short gastric vessels. In this review article the authors evaluate the most recent articles to establish the parameters for a "gold standard technique" in antireflux surgery

Computational investigation of the electron transfer complex between neuroglobin and cytochrome c

Neuroglobin (Ngb) was the first vertebrate nerve globin to be identified. Since then, different physiological roles have been hypothesised for this hexa-coordinated globin, but its function is far from being unambiguously assigned. In a previous work, we collected first evidences of Ngb potentially taking part to electron transfer (ET) processes in vivo, investigating the redox thermodynamics of this globin. Here, we perform a computational investigation on the complex between Ngb and its putative in vivo partner cyt c and on the ET process between the two species. The simulated structure of the complex is amenable for ET in terms of distance and relative protein orientation. Moreover, the redox-dependent stability of the predicted Ngb-cyt c adduct and the very good agreement between calculated determinants to the ET rate and those of paradigmatic metalloproteins acting as electron shuttles all support a potential role of neuroglobin as an electron transfer species

A multi-element psychosocial intervention for early psychosis (GET UP PIANO TRIAL) conducted in a catchment area of 10 million inhabitants: study protocol for a pragmatic cluster randomized controlled trial

Multi-element interventions for first-episode psychosis (FEP) are promising, but have mostly been conducted in non-epidemiologically representative samples, thereby raising the risk of underestimating the complexities involved in treating FEP in 'real-world' services