The European Commission and International Trade Negotiations: A Principal-Agent Approach. IES WORKING PAPER 2/2011

Starting from the concept of delegation of power in external trade policy, this paper aims to investigate the dynamics surrounding the European Union’s position in international trade negotiations. The analysis centres on the role of the European Commission (the agent), which by means of Treaty-based delegation and as mandated by the Council (the principal) acts as the sole trade negotiator in the international sphere on behalf of the European Union (EU). The broader negotiating process is thus conceptualised as a threelevel game, where the Commission holds an intermediary position between the European and international levels and also interacts with the Member States in the Council. After an insight into the European decision-making process for external trade, the paper further analyses the Commission’s role during the multilateral trade negotiations of the Doha Development Round. By applying the principal-agent theory to international trade negotiations in general, and subsequently to the controversial agricultural negotiations, this paper seeks to investigate some of the potential sources of autonomy that the Commission can draw upon while upholding an EU position at the international level, in addition to the “hardball” job of balancing the interests of the Member States with those of World Trade Organisation (WTO) partners. Along these lines, the paper finally aims to contribute to the literature concerning agency autonomy in EU external trade relations but also to provide a better understanding of inter-institutional relations within the EU as they may unfold in practice

Statistics of radiation at Josephson parametric resonance

Motivated by recent experiments, we study theoretically the full counting statistics of radiation emitted below the threshold of parametric resonance in a Josephson junction circuit. In contrast to most optical systems, a significant part of emitted radiation can be collected and converted to an output signal. This permits studying the correlations of the radiation. To quantify the correlations, we derive a closed expression for full counting statistics in the limit of long measurement times. We demonstrate that the statistics can be interpreted in terms of uncorrelated bursts each encompassing 2N photons, this accounts for the bunching of the photon pairs produced in course of the parametric resonance. We present the details of the burst rates. In addition, we study the time correlations within the bursts and discuss experimental signatures of the statistics deriving the frequency-resolved cross-correlations.Comment: 12 pages, 7 figure

DIVORCE PROCEEDINGS, IN LIGHT OF THE NEW PROVISIONS OF LAW NO. 202/2010 REGARDING SOME MEASURES FOR ACCELERATING THE RESOLUTION PROCESS

Law no. 202/2010 regarding some measures for accelerating the resolution process establishes procedural rules with immediate effect, meant to streamline judicial procedures, and to expeditiously resolve processes, regulating specific legislative measures, which aim mainly to simplify solving cases. In matters of divorce, a first change is that, unlike the previous situation, the divorce case by agreement will be judged in the council chamber. Also, according to the above mentioned law, if the conditions for dissolution by agreement are accomplished, we can divorce not only in front of the court, but also to the notary public or officer of civil status, opportunity that did not existed in past. Another novelty is the express possibility to demand resolution through mediation for divorce, specifying that the parties can not only refuse the judge's recommendation to seek mediation, but that the parties can refuse mediation session even after information. Regarding mediation, the law brings news on divorce. Under that legislation, divorce can be made by the parties even when the couple has minor children and agree to the mediation process

Shimura curves admitting a smooth plane model

We prove that there are no Shimura curves $X_0^D(N)$ of squarefree level and of genus at least two admitting a smooth plane model.Comment: 7 page

Superconducting Spin Qubits

We propose and theoretically investigate spin superconducting qubits. Spin superconducting qubit consists of a single spin confined in a Josephson junction. We show that owing to spin-orbit interaction, superconducting difference across the junction can polarize this spin. We demonstrate that this enables single qubit operations and more complicated quantum gates, where spins of different qubits interact via a mutual inductance of superconducting loop where the junctions are embedded. Recent experimental realizations of Josephson junctions made of semiconductor quantum dots in contact with superconducting leads have shown that the number of electrons in the quantum dot can be tuned by a gate voltage. Spin superconducting qubit is realized when the number of electrons is odd. We discuss the qubit properties at phenomenological level. We present a microscopic theory that enables us to make accurate estimations of the qubit parameters by evaluating the spin-dependent Josephson energy in the framework of fourth-order perturbation theory.Comment: 11 pages, 8 figure

Rational points on Atkin-Lehner quotients of geometrically hyperelliptic Shimura curves

Guo and Yang give defining equations for all geometrically hyperelliptic Shimura curves $X_0(D,N)$. In this paper we compute the $\mathbb{Q}$-rational points on the Atkin-Lehner quotients of these curves using a variety of techniques. We also determine which rational points are CM for many of these curves.Comment: 23 pages. Comments welcome

CARDIOVASCULAR RISK FACTORS AS POTENTIAL MARKERS FOR MILD COGNITIVE IMPAIRMENT AND ALZHEIMER’S DISEASE

Background: Mild cognitive impairment (MCI) is an early stage of cognitive decline that has a significant risk of converting to dementia. Cardiovascular pathology appears to have a major impact in cognitive decline, and it is clear that early identification and correction of cardiovascular morbidity could have a major impact on cognitive functioning. Subjects and methods: Our study was conducted in order to identify some cardiovascular risk factors among patients with cognitive decline (MCI or Alzheimer disease-AD) and to find if there is any correlation with the degree of cognitive decline. We evaluated the body mass index, total cholesterol, hypertension, history of smoking, alcohol consumption and diabetes mellitus in patients with MCI and AD, compared with an age-matched control group. Results: Regarding the body mass index, we observed a progressive decrease in patients with MCI and AD, in comparison with the control group. Similar aspects were also observed in the case of cholesterol levels, only that post hoc analysis revealed no significantly statistical differences between MCI and AD groups. The systolic blood pressure was increased in the patients with MCI and AD. Also, as in the case of cholesterol levels, post hoc analysis revealed no significantly statistical differences between MCI and AD groups. Pearson’s correlation showed significant connections between the cardiovascular risk factors and the results of the cognitive evaluation. Conclusions: Our results constitute additional evidence that cardiovascular risk factors are involved in cognitive regression. This finding could have an important impact on the management of dementia

Best Practices and Pitfalls in Commercializing IVD-Applicable Biomarkers

Before biomarker discoveries can be commercially utilized in clinical laboratories, many studies and surveys need to be completed and many questions answered. Is there a market need? Is there enough scientific and clinical evidence to convince the end users? Is the biomarker patentable? Is the translation into a practical product feasible? Although commercial product development is not the focus of academic research, the route to reach the patients will almost always require a professional commercialization process. Understanding industry and end-user requirements is essential for the successful commercialization of new biomarker assays. The current handbook collects some of the best practices and pitfalls encountered at different phases of biomarker discovery, development, patent protection and technology transfer at universities, hospitals and research organizations. The focus is on in vitro diagnostics (IVD)-applicable biomarkers, i.e. markers intended to provide information on the health status of a person. The input for the collection has been sought from true-life practices: practices found in literature or taught by experts in the field; opinions and expertise of different stakeholders (end users, companies, technology transfer professionals, researchers, financiers); recommendations, regulation and laws; as well as practices learned the hard way, i.e. repeatedly failing somewhere in the process and later adapting the process for increased success. The main target group of the handbook comprises professionals working in Technology Transfer Offices (TTOs). The presented practices are yet not intended to be interpreted as strict rules but rather as a source of inspiration. Optimal ways to proceed with patenting and commercialization significantly vary between cases and circumstances.The handbook has been prepared within the EU-project Biomarker Commercialization (BIC) comprising 9 partners in the Baltic Sea Region (BSR) united with the same challenges, as well as the common objective of more efficiently bringing new and better IVD-applicable biomarkers from discovery into clinical use. The project's budget is EUR 2.55 million and is co-financed by the European Regional Development Fund through the Interreg Baltic Sea Region Programme with EUR 1.96 million