24,234 research outputs found
Resistivity due to low-symmetrical defects in metals
The impurity resistivity, also known as the residual resistivity, is
calculated ab initio using multiple-scattering theory. The mean-free path is
calculated by solving the Boltzmann equation iteratively. The resistivity due
to low-symmetrical defects, such as an impurity-vacancy pair, is calculated for
the FCC host metals Al and Ag and the BCC transition metal V. Commonly, 1/f
noise is attributed to the motion of such defects in a diffusion process.Comment: 24 pages in REVTEX-preprint format, 10 Postscript figures. Phys. Rev.
B, vol. 57 (1998), accepted for publicatio
Significant familial differences in the frequency of abortion and Toxoplasma gondii infection within a flock of Charollais sheep
A study was carried out to investigate the frequencies of abortion and congenital Toxoplasma gondii infection within 27
families (765 individuals) of a pedigree Charollais sheep flock maintained on a working farm in Worcestershire, UK, since
1992. Pedigree lambing records were analysed to establish the frequency of abortion for each family. The frequency of
congenital infection was determined for each family by PCR analysis of tissue samples taken from newborn lambs. Atotal of
155 lambs were tested for congenital T. gondii infection, which were all born during the study period 2000–2003. Significant
differences in the frequency of abortion between sheep families within this flock were observed with frequencies ranging
between 0% and 48% (P<0.01). Significantly different infection frequencies with T. gondii were also observed for different
families and ranged between 0% and 100% (P<0.01). Although the actual cause of each abortion was not verified, a highly
significant positive correlation was found to exist between the frequency of abortion and the frequency of T. gondii infection
in the same families (P<0.01). The data presented here raise further questions regarding the significance of congenital
transmission of T. gondii within sheep populations, the possible successive vertical transmission of T. gondii within families
of sheep, and the potential role of inherited genetic susceptibility to abortion with respect to T. gondii infection. This work
invites further study into the epidemiology of ovine toxoplasmosis and may have implications for sheep husbandry methods
in the future.
Key words: Toxoplasma gondii, ovine, toxoplasmosis, congenital, transmission, pedigree, sheep
High levels of congenital transmission of toxoplasma gondii in longitudinal and cross-sectional studies on sheep farms provides evidence of vertical transmission in ovine hosts
Recent research suggests that vertical transmission may play an important role in sustaining Toxoplasma gondii infection in some species. We report here that congenital transmission occurs at consistently high levels in pedigree Charollais and outbred sheep flocks sampled over a 3-year period. Overall rates of transmission per pregnancy determined by PCR based diagnosis, were consistent over time in a commercial sheep flock (69%) and in sympatric (60%) and allopatric (41%) populations of Charollais sheep. The result of this was that 53·7% of lambs were acquiring an infection prior to birth: 46·4% of live lambs and 90·0% of dead lambs (in agreement with the association made between T. gondii and abortion). No significant differences were observed between lamb sexes. Although we cannot distinguish between congenital transmission occurring due to primary infection at pregnancy or reactivation of chronic infection during pregnancy, our observations of consistently high levels of congenital transmission over successive lambings favour the latter
Social mobility and inflammatory and metabolic markers at older ages: the English Longitudinal Study of Ageing
BACKGROUND: Since our knowledge of the associations between socioeconomic position (SEP) over the life course and inflammatory and metabolic markers, which are excellent predictors of cardiovascular disease, remains limited, we examined the association between social mobility over the life course and these markers at older ages. METHODS: Our study used cross-sectionally collected data from 6142 participants aged 50 years and older from the English Longitudinal Study of Ageing. We estimated linear and logistic models of the associations between social mobility, using information on childhood and adult SEP, C reactive protein (CRP), fibrinogen, glycated haemoglobin (HbA1c) and high-density lipoprotein (HDL) cholesterol. Our models were gradually adjusted for age, sex, chronic diseases, obesity, physical activity, alcohol consumption, smoking status and depressive symptoms. RESULTS: Participants who experienced upward social mobility had higher CRP, fibrinogen and HbA1c levels compared with those who had stable high SEP over the life course, but lower compared with those who experienced downward social mobility or had stable low SEP. They also had lower HDL levels compared with those who had stable high SEP or downwardly mobile. Adjustment for covariates partially explained the associations between social mobility and CRP and HDL, and fully explained those between social mobility and fibrinogen and HbA1c. CONCLUSIONS: Social mobility is associated with inflammatory and metabolic markers at older ages with some of the observed associations persisting after accounting for covariates. Upward social mobility appears to partially reverse the damaging effect of childhood social disadvantage on inflammatory profiles in older ages
Atomic level micromagnetic model of recording media switching at elevated temperatures
An atomic level micromagnetic model of granular recording media is developed
and applied to examine external field-induced grain switching at elevated
temperatures which captures non-uniform reversal modes. The results are
compared with traditional methods which employ the Landau-Lifshitz-Gilbert
equations based on uniformly magnetized grains with assigned intrinsic
temperature profiles for and . Using nominal parameters
corresponding to high-anisotropy FePt-type media envisioned for Energy Assisted
Magnetic Recording, our results demonstrate that atomic-level reversal slightly
reduces the field required to switch grains at elevated temperatures, but
results in larger fluctuations, when compared to a uniformly magnetized grain
model.Comment: 4 pages, 5 figure
Micromagnetic simulations of sweep-rate dependent coercivity in perpendicular recording media
The results of micromagnetic simulations are presented which examine the
impact of thermal fluctuations on sweep rate dependent coercivities of both
single-layer and exchange-coupled-composite (ECC) perpendicular magnetic
recording media. M-H loops are calculated at four temperatures and sweep rates
spanning five decades with fields applied normal to the plane and at 45
degrees. The impact of interactions between grains is evaluated. The results
indicate a significantly weaker sweep-rate dependence for ECC media suggesting
more robustness to long-term thermal effects. Fitting the modeled results to
Sharrock-like scaling proposed by Feng and Visscher [J. Appl. Phys. 95, 7043
(2004)] is successful only in the case of single-layer media with the field
normal to the plane.Comment: 7 pages, 14 figure
Quantum field theoretic approach to neutrino oscillations in matter
We consider neutrino oscillations in non-uniform matter in a quantum field
theoretic (QFT) approach, in which neutrino production, propagation and
detection are considered as a single process. We find the conditions under
which the oscillation probability can be sensibly defined and demonstrate how
the properly normalized oscillation probability can be obtained in the QFT
framework. We derive the evolution equation for the oscillation amplitude and
discuss the conditions under which it reduces to the standard
Schr\"odinger-like evolution equation. It is shown that, contrary to the common
usage, the Schr\"odinger-like evolution equation is not applicable in certain
cases, such as oscillations of neutrinos produced in decays of free pions
provided that sterile neutrinos with eV exist.Comment: LaTeX, 24 pages + 16 pages of appendices, 1 figure. V2: typos
correcte
An action principle for the quantization of parametric theories and nonlinear quantum cosmology
By parametrizing the action integral for the standard Schrodinger equation we
present a derivation of the recently proposed method for quantizing a
parametrized theory. The reformulation suggests a natural extension from
conventional to nonlinear quantum mechanics. This generalization enables a
unitary description of the quantum evolution for a broad class of constrained
Hamiltonian systems with a nonlinear kinematic structure. In particular, the
new theory is applicable to the quantization of cosmological models where a
chosen gravitational degree of freedom acts as geometric time. This is
demonstrated explicitly using three cosmological models: the Friedmann universe
with a massless scalar field and Bianchi type I and IX models. Based on these
investigations, the prospect of further developing the proposed quantization
scheme in the context of quantum gravity is discussed.Comment: 14 page
Up on the roof: a review of design, construction, and technology trends in vertical extensions
New spaces to accommodate growing urban populations should be created in a way that also reduces building lifecycle carbon emissions. In this context, the vertical extension (VE) has emerged as a novel building typology that can increase space in cities through the construction of additional floor area atop existing base buildings. This paper presents a review of 172 VE projects worldwide to provide an understanding of their design and construction trends, and to classify the technologies applied. Results show that VE construction has accelerated significantly over the past decade. Although most VEs consist of only small vertical additions, often one to two storeys, higher VEs can be built with innovative structural strategies and lightweight materials. Industrial buildings are often found to provide significant opportunities for VE due to their higher structural capacity. By comparing the characteristics and design of VEs, typologies based on architectural, structural, and construction technologies are presented
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