Statistical analysis and modelling of weather radar beam propagation conditions in the Po Valley (Italy)

Ground clutter caused by anomalous propagation (anaprop) can affect seriously radar rain rate estimates, particularly in fully automatic radar processing systems, and, if not filtered, can produce frequent false alarms. A statistical study of anomalous propagation detected from two operational C-band radars in the northern Italian region of Emilia Romagna is discussed, paying particular attention to its diurnal and seasonal variability. The analysis shows a high incidence of anaprop in summer, mainly in the morning and evening, due to the humid and hot summer climate of the Po Valley, particularly in the coastal zone. Thereafter, a comparison between different techniques and datasets to retrieve the vertical profile of the refractive index gradient in the boundary layer is also presented. In particular, their capability to detect anomalous propagation conditions is compared. Furthermore, beam path trajectories are simulated using a multilayer ray-tracing model and the influence of the propagation conditions on the beam trajectory and shape is examined. High resolution radiosounding data are identified as the best available dataset to reproduce accurately the local propagation conditions, while lower resolution standard TEMP data suffers from interpolation degradation and Numerical Weather Prediction model data (Lokal Model) are able to retrieve a tendency to superrefraction but not to detect ducting conditions. Observing the ray tracing of the centre, lower and upper limits of the radar antenna 3-dB half-power main beam lobe it is concluded that ducting layers produce a change in the measured volume and in the power distribution that can lead to an additional error in the reflectivity estimate and, subsequently, in the estimated rainfall rate

Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue

In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used. In our opinion the data suggest that placebo and drug effects are non-additive: antidepressants act independently of depression severity, while the placebo effect is present only in milder cases. While the response in the placebo group is due to unstable ‘noise’ and ‘artefacts’, the medication effect is reliable, valid and stable

Quality of life and well-being of carers of people with dementia: are there differences between working and nonworking carers? Results from the IDEAL program

The aim of this study was to identify the differences in quality of life (QoL) and well-being between working and nonworking dementia carers and the relative contribution of psychological characteristics, caregiving experience, and social support. Multiple regressions modeled the contribution of working status, caregiver experiences, and psychological and social resources to carer QoL (EQ-5D) and well-being (WHO-5). After controlling for age, gender, carer–dyad relationship, and severity of dementia, working status contributed significant variance to EQ-5D (2%) but not to WHO-5 scores. Independent of working status, higher self-esteem and reduced stress contributed to variance in both models. Self-efficacy, social support, and positive perceptions of caregiving additionally contributed to higher WHO-5 scores. Working status associated with higher EQ-5D QoL; this may reflect the sustained sense of independence associated with supported work opportunities for carers. Outside of working status, the findings support the importance of psychological and social factors as targets to improved mental health for dementia carers

The Pharmacopsychometric Triangle to Illustrate the Effectiveness of T-PEMF Concomitant with Antidepressants in Treatment Resistant Patients: A Double-Blind, Randomised, Sham-Controlled Trial Revisited with Focus on the Patient-Reported Outcomes

Background. Our T-PEMF trial has been revisited with focus on the pharmacopsychometric triangle in which effect size is used when comparing wanted versus unwanted clinical effects and quality of life as outcomes. In this analysis, we have especially focused on the self-reported HAM-D6. Methods. The antidepressive medication which the patients were resistant to was kept unchanged during the five weeks of active versus sham T-PEMF. Results. In total 21, patients received active T-PEMF, and 19 patients received sham T-PEMF. The effect size was 1.02 and 0.90, respectively, on HAM-D6 and HAM-D6-S. Concerning side effects, the active T-PEMF reduced the baseline score on concentration problems with an effect size of 0.44 while inducing more autonomic symptoms than sham T-PEMF with an effect size of −0.41. The advantage of active over sham T-PEMF obtained an effect size of 0.48. Conclusion. Active T-PEMF was found superior to sham T-PEMF within the pharmacopsychometric triangle with a clinically significant effect size level above 0.40

On the Phenomenology of Hydrodynamic Shear Turbulence

The question of a purely hydrodynamic origin of turbulence in accretion disks is reexamined, on the basis of a large body of experimental and numerical evidence on various subcritical (i.e., linearly stable) hydrodynamic flows. One of the main points of this paper is that the length scale and velocity fluctuation amplitude which are characteristic of turbulent transport in these flows scale like $Re_m^{-1/2}$, where $Re_m$ is the minimal Reynolds number for the onset of fully developed turbulence. From this scaling, a simple explanation of the dependence of $Re_m$ with relative gap width in subcritical Couette-Taylor flows is developed. It is also argued that flows in the shearing sheet limit should be turbulent, and that the lack of turbulence in all such simulations performed to date is most likely due to a lack of resolution, as a consequence of the effect of the Coriolis force on the large scale fluctuations of turbulent flows. These results imply that accretion flows should be turbulent through hydrodynamic processes. If this is the case, the Shakura-Sunyaev $\alpha$ parameter is constrained to lie in the range $10^{-3}-10^{-1}$ in accretion disks, depending on unknown features of the mechanism which sustains turbulence. Whether the hydrodynamic source of turbulence is more efficient than the MHD one where present is an open question.Comment: 31 pages, 3 figures. Accepted for publication in Ap

Implementation of the Multiple Point Principle in the Two-Higgs Doublet Model of type II

The multiple point principle (MPP) is applied to the non--supersymmetric two-Higgs doublet extension of the Standard Model (SM). The existence of a large set of degenerate vacua at some high energy scale caused by the MPP results in a few relations between Higgs self-coupling constants which can be examined at future colliders. The numerical analysis reveals that these MPP conditions constrain the mass of the SM--like Higgs boson to lie below 180 GeV for a wide set of MPP scales $\Lambda$ and $\tan\beta$.Comment: 26 pages, 3 figures, some minor changes to the tex

Design Aspects on Winding of an MgB₂ Superconducting Generator Coil

AbstractGenerators based on superconducting rotor coils are considered for future large off-shore wind turbines for their low weight and compact design, and for their possibility to reduce costs. In the 10-20 K temperature range, MgB2 superconductors carry current densities 100 times higher than standard copper conductors at room temperature at one tenth of the wire cost per unit carried current. In the framework of the European project INNWIND.EU, an MgB2 superconducting generator pole will be designed, built and tested. Some of the design aspects of this work with emphasis on the winding process and associated coil insulation are discussed. An overall high current density in the coil is of crucial importance to obtain clear benefits compared to conventional solutions. The wire itself may be the most important parameter in that respect. However, the overall current density of the coil is also influenced by the thickness of the turn-to-turn electrical insulation. Here we discuss the impact of the insulation and suggest the use of a one-step winding process, employing wet-winding, where the applied epoxy also constitutes the insulation layer between turns. In this way the coil is densified by approximately 10% compared to the use of an additional, dedicated, electrical insulation like Kapton for wet-winding or glass-fibre for dry-winding followed by vacuum impregnation. We show the results of a trial winding of 500 m of MgB2 superconducting wire into a double pancake coil using the wet-winding technique. The coil is tested for contacts between the turns to evaluate the suggested one-step wet-winding process