The aphasia rapid test:Adaptation and standardisation for Russian

Background: The Aphasia Rapid Test (ART) is a screening test developed for fast speech/language assessment of people in the acute stroke period. This test has been developed for French and English and was recently adapted for Portuguese and Italian. Nowadays, such a standardised screening test is in a great need at clinics with Russian-speaking patients. To fill this gap, the ART was adapted for Russian. Aims: The current study investigated whether the Russian ART meets all the psychometric standards, and whether it is suitable for detecting speech/language disorders and estimating their severity, as well as for the evaluation of improvement in the acute post-stroke period. Methods & Procedure: First, we evaluated the validity, sensitivity, specificity, accuracy, test-retest reliability, inter-item consistency and inter-rater reliability of the test in a group of people with chronic speech/language disorders (N = 55) and in an age-matched control group of non-brain-damaged individuals (N = 50). Participants performed the Russian ART, and their linguistic status was confirmed by the Russian e-version of the Token Test. Second, to test the appropriateness of the Russian ART in the acute post-stroke period, a clinical group of such individuals (N = 43) performed the ART and the Token Test, as well as the Vasserman's scale which is widely used in Russian clinics. Finally, 16 people in the acute stroke period performed the Russian ART twice to prove that the test can detect early changes in an acute patient's linguistic status. Outcomes & Results: The results showed that the Russian ART can be considered as a valid, sensitive, specific, and accurate screening tool with the high test-retest reliability, inter-item consistency, and inter-rater reliability. In the acute post-stroke group, the correlation between the ART and the Token Test was high and significant; a moderate correlation and no significant correlation were found between the Vasserman's scale and the Russian ART and the Token Test correspondingly. The Russian ART also allowed us to detect the improvement in speech/language status in the acute post-stroke period. Conclusion: The study confirmed that the Russian ART meets all required standards to be suggested for usage in a Russian-speaking clinical population. This test was relevant for detecting the presence and severity of speech/language disorders and to measure the improvement in the acute post-stroke period

Aspect and tense attrition in Russian-German bilingual speakers

Purpose: The impact of second language (L2) on first language (L1), known as L2 transfer, has been suggested as a fundamental driving force of L1 attrition. The goal of this study was to test the differential attrition of verb aspect and tense in L1 (Russian) under the influence of L2 (German) grammatical properties. We also investigated whether the age of bilingualism onset and the amount of exposure to L1 modulate this L2 transfer effect. Methodology: We tested sentence processing in 30 adult Russian monolingual participants and 30 L1 attritors - Russian-German bilingual speakers - with early versus late bilingualism onset and with low versus high amounts of exposure to L1. Participants heard grammatically correct sentences, sentences with aspect violations and sentences with tense violations, and were asked to detect errors. Data and Analysis: The accuracy of participants' responses was analysed using generalized linear mixed-effects modelling in R. Findings: The L2 transfer effect was found, but was strongly modulated by the amount of L1 exposure: only bilinguals with little exposure to L1 showed greater attrition of L1 aspect compared to L1 tense. Moreover, the age of bilingualism onset proved to be more critical than the L2 transfer effect: an earlier bilingualism onset resulted in greater attrition of both aspect and tense in L1. Originality: The study provided new evidence about the differential impact of the grammatical similarity between L1 and L2, the age of bilingualism onset and the amount of L1 exposure on aspect and tense processing in L1

Retrieval and Encoding Interference: Cross-Linguistic Evidence from Anaphor Processing

The main goal of this paper was to disentangle encoding and retrieval interference effects in anaphor processing and thus to evaluate the hypothesis predicting that structurally inaccessible nouns (distractors) are not considered to be potential anaphor antecedents during language processing (Nicol and Swinney, 1989). Three self-paced reading experiments were conducted: one in German, comparing gender-unmarked reflexives and gender-marked pronouns, and two in Russian, comparing gender-marked and -unmarked reflexives. In the German experiment, no interference effects were found. In the first experiment in Russian, an unexpected reading times pattern emerged: in the condition where the distractor matched the gender of the reflexive's antecedent, reading of the gender-unmarked, but not the gender-marked reflexives was slowed down. The same reading times pattern was replicated in a second experiment in Russian where the order of the reflexive and the main verb was inverted. We conclude that the results of the two experiments in Russian are inconsistent with the retrieval interference account, but can be explained by encoding interference and additional semantic processing efforts associated with the processing of gender-marked reflexives. In sum, we found no evidence that would allow us to reject the syntax as an early filer account (Nicol and Swinney, 1989)

Implicit-statistical learning in aphasia and its relation to lesion location

Background: Implicit-statistical learning (ISL) research investigates whether domain-general mechanisms are recruited in the linguistic processes that require manipulation of patterned regularities (e.g. syntax). Aphasia is a language disorder caused by focal brain damage in the left fronto-temporal-parietal network. Research shows that people with aphasia (PWA) with frontal lobe lesions manifest convergent deficits in syntax and ISL mechanisms. So far, ISL mechanisms in PWA with temporal or parietal lobe lesions have not been systematically investigated. Aims: We investigated two complementary hypotheses: 1) the anatomical hypothesis, that PWA with frontal lesions display more severely impaired ISL abilities than PWA with posterior lesions and 2) the behavioural hypothesis, that the magnitude of impairment in ISL mechanisms correlates to syntactic deficits in aphasia. Methods: We tested 13 PWA, 5 with frontal lesions and 8 with posterior lesions, and 11 non-brain-damaged controls on a visual statistical learning (VSL) task. In addition, all PWA completed several linguistic tasks. Reaction times, obtained in the VSL task, were analyzed using linear mixed-effects model. Correlational statistics were used to assess the relationship between VSL task performance and linguistic measures. Results and Discussion: We did not find support for the anatomical hypothesis as patients with spared frontal regions also manifested impaired ISL mechanisms. This is attributed to a) ISL mechanisms being vulnerable to other cognitive dysfunctions and/or b) ISL mechanisms anatomically extending to the posterior brain regions. Notably, ISL mechanisms were impaired, but not absent in aphasia. With regards to the behavioural hypothesis, we provide empirical evidence of correlation between ISL mechanisms and syntactic, but not lexical impairment in aphasia. We discuss both the theoretical contributions to the debate of domain-independence of ISL mechanisms and clinical implications for implicit language therapy

Augmented reality for the virtual dissection of white matter pathways

Background: The human white matter pathway network is complex and of critical importance for functionality. Thus, learning and understanding white matter tract anatomy is important for the training of neuroscientists and neurosurgeons. The study aims to test and evaluate a new method for fiber dissection using augmented reality (AR) in a group which is experienced in cadaver white matter dissection courses and in vivo tractography. Methods: Fifteen neurosurgeons, neurolinguists, and neuroscientists participated in this questionnaire-based study. We presented five cases of patients with left-sided perisylvian gliomas who underwent awake craniotomy. Diffusion tensor imaging fiber tracking (DTI FT) was performed and the language-related networks were visualized separated in different tracts by color. Participants were able to virtually dissect the prepared DTI FTs using a spatial computer and AR goggles. The application was evaluated through a questionnaire with answers from 0 (minimum) to 10 (maximum). Results: Participants rated the overall experience of AR fiber dissection with a median of 8 points (mean ± standard deviation 8.5 ± 1.4). Usefulness for fiber dissection courses and education in general was rated with 8 (8.3 ± 1.4) and 8 (8.1 ± 1.5) points, respectively. Educational value was expected to be high for several target audiences (student: median 9, 8.6 ± 1.4; resident: 9, 8.5 ± 1.8; surgeon: 9, 8.2 ± 2.4; scientist: 8.5, 8.0 ± 2.4). Even clinical application of AR fiber dissection was expected to be of value with a median of 7 points (7.0 ± 2.5). Conclusion: The present evaluation of this first application of AR for fiber dissection shows a throughout positive evaluation for educational purposes

Verb production and word order in Russian agrammatic speakers

Background: Verb production has been shown to be impaired in individuals with agrammatic Broca's aphasia. Several theories have linked this deficit to problems with the implementation of grammatical information that the verb contains. In particular, the number and type of arguments associated with a verb were suggested as causes of production difficulties in agrammatic speakers. The influence of these two factors on agrammatic production has been investigated in English and Dutch (Bastiaanse Van Zonneveld, 2005; Thompson, 2003). Aims: The present study focuses on exploring these factors in a structurally different language. Russian, with its rich morphology and relatively free word order, is of interest because it enables not only testing of earlier advanced hypotheses on agrammatic production, but also specification of them at some essential points. Methods Procedures: A sentence production priming paradigm was used that was based on the method developed by Thompson, Lange, Schneider, and Shapiro (1997) which allows a particular verb and sentence construction to be elicited. Six conditions included sentences with different numbers of arguments (one or two), different types of thematic role mapping (direct or indirect), and different word order (basic or scrambled). The test contained 60 items, 10 items per condition. In all, 16 individuals with agrammatic aphasia and 16 non-brain-damaged individuals participated in the study. Outcomes Results: Cross-linguistic significance of the earlier advanced hypotheses was demonstrated: the increased number of verb arguments and syntactic operations concerning constituent movement cause production problems for Russian agrammatic speakers. Moreover, the data show that agrammatic speech difficulties are related to the number of arguments explicitly mentioned in a sentence, to the number of operations applied to the syntactic structure of a produced sentence, and to changing the base-generated position of a constituent (not to the order of the constituents per se). Conclusions: The study provides further evidence that verb production is selectively impaired in agrammatic aphasia. This deficit is related to the implementation of the grammatical information that a verb contains and the syntactic operations applied to basic structures

The Mental Representation of Polysemy across Word Classes

Experimental studies on polysemy have come to contradictory conclusions on whether words with multiple senses are stored as separate or shared mental representations. The present study examined the semantic relatedness and semantic similarity of literal and non-literal (metonymic and metaphorical) senses of three word classes: nouns, verbs, and adjectives. Two methods were used: a psycholinguistic experiment and a distributional analysis of corpus data. In the experiment, participants were presented with 6–12 short phrases containing a polysemous word in literal, metonymic, or metaphorical senses and were asked to classify them so that phrases with the same perceived sense were grouped together. To investigate the impact of professional background on their decisions, participants were controlled for linguistic vs. non-linguistic education. For nouns and verbs, all participants preferred to group together phrases with literal and metonymic senses, but not any other pairs of senses. For adjectives, two pairs of senses were often grouped together: literal with metonymic, and metonymic with metaphorical. Participants with a linguistic background were more accurate than participants with non-linguistic backgrounds, although both groups shared principal patterns of sense classification. For the distributional analysis of corpus data, we used a semantic vector approach to quantify the similarity of phrases with literal, metonymic, and metaphorical senses in the corpora. We found that phrases with literal and metonymic senses had the highest degree of similarity for the three word classes, and that metonymic and metaphorical senses of adjectives had the highest degree of similarity among all word classes. These findings are in line with the experimental results. Overall, the results suggest that the mental representation of a polysemous word depends on its word class. In nouns and verbs, literal and metonymic senses are stored together, while metaphorical senses are stored separately; in adjectives, metonymic senses significantly overlap with both literal and metaphorical senses

Toward a functional neuroanatomy of semantic aphasia:A history and ten new cases

Almost 70 years ago, Alexander Luria incorporated semantic aphasia among his aphasia classifications by demonstrating that deficits in linking the logical relationships of words in a sentence could co-occur with non-linguistic disorders of calculation, spatial gnosis and praxis deficits. In line with his comprehensive approach to the assessment of language and other cognitive functions, he argued that deficits in understanding semantically reversible sentences and prepositional phrases, for example, were in line with a single neuropsychological factor of impaired spatial analysis and synthesis, since understanding such grammatical relationships would also draw on their spatial relationships. Critically, Luria demonstrated the neural underpinnings of this syndrome with the critical implication of the cortex of the left temporal-parietal-occipital (TPO) junction. In this study, we report neuropsychological and lesion profiles of 10 new cases of semantic aphasia. Modern neuroimaging techniques provide support for the relevance of the left TPO area for semantic aphasia, but also extend Luria's neuroanatomical model by taking into account white matter pathways. Our findings suggest that tracts with parietal connectivity the arcuate fasciculus (long and posterior segments), the inferior fronto-occipital fasciculus, the inferior longitudinal fasciculus, the superior longitudinal fasciculus II and III, and the corpus callosum are implicated in the linguistic and non-linguistic deficits of patients with semantic aphasia. (C) 2016 Elsevier Ltd. All rights reserved

Testing the continuum/spectrum model in Russian-speaking children with and without developmental language disorder

Purpose: Previously, Lancaster and Camarata (2019) showed that the continuum/spectrum model of the developmental language disorder (DLD) best explained the high heterogeneity of symptoms in children with DLD. We hypothesize that the continuum/spectrum approach can include not only children with DLD, but also typically developing children with different timelines and patterns of language acquisition. This model can explain individual language profiles and deficits in children. Method: We assessed language abilities in a group of Russian-speaking children with DLD aged 4-to-7 years (N = 53) and their age- and gender-matched peers without speech and language diagnoses (N = 53, TD). We evaluated the children’s performance at four language levels in production and comprehension domains, using 11 subtests of the standardized language assessment for Russian – RuCLAB. Using the k-means cluster method and RuCLAB scores, we obtained two clusters of children and analyzed their language performance in individual subtests. Results: The analysis revealed that the two clusters of children both included DLD and TD participants: Group 1, with higher test scores (TD = 45, DLD = 24 children) and Group 2, with lower scores (TD = 8, DLD = 29). Children from Group 1 mostly had lower scores at one of the language levels, whereas those from Group 2 struggled at several language levels. Furthermore, children with DLD from both Groups tended to be more sensitive to linguistic features like word length, noun case, sentence reversibility compared to TD children. Conclusions: The presence of two mixed groups shows that children with diagnosed DLD could perform on par with TD children, whereas some younger TD children could perform similarly to children with DLD. Our findings support the continuum/spectrum model: linguistic skills in pre-school children are a continuum, varying from high to poor skills at all language levels in comprehension and production. To describe a child’s language profile, the tasks assessing all language levels should be used