188 research outputs found
Quantitative estimation of tissue blood flow rate
The rate of blood flow through a tissue (F) is a critical parameter for assessing the functional efficiency of a blood vessel network following angiogenesis. This chapter aims to provide the principles behind the estimation of F, how F relates to other commonly used measures of tissue perfusion, and a practical approach for estimating F in laboratory animals, using small readily diffusible and metabolically inert radio-tracers. The methods described require relatively nonspecialized equipment. However, the analytical descriptions apply equally to complementary techniques involving more sophisticated noninvasive imaging. Two techniques are described for the quantitative estimation of F based on measuring the rate of tissue uptake following intravenous administration of radioactive iodo-antipyrine (or other suitable tracer). The Tissue Equilibration Technique is the classical approach and the Indicator Fractionation Technique, which is simpler to perform, is a practical alternative in many cases. The experimental procedures and analytical methods for both techniques are given, as well as guidelines for choosing the most appropriate method
Mercury and selenium in fish of Fountain Creek, Colorado (USA): possible sources and implications
Expensive cerebral blood flow measurements alone are useless and misinformative in comatose patients: a comprehensive alternative
Characterising microbial protein test substances and establishing their equivalence with plant-produced proteins for use in risk assessments of transgenic crops
Measurement of activated rCBF by the 133Xe inhalation technique: a comparison of total versus partial curve analysis.
Effect of Xenon-Induced Flow Activation on Xenon-Enhanced Computed Tomography Cerebral Blood Flow Calculations
Effect of stable xenon on regional cerebral blood flow and the electroencephalogram in normal volunteers.
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