Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

DPA8993-KN.Dissertation III.Sp16.Norman-Major,Kristen

Independent work with chair/mentor to write chapter 3 (Methodology) and get IRB approval. Completion will then lead to Dissertation Proposal Defense (provided comprehensive exams have been passed)

GPA8506-DPA.AdvancedSeminarInPublicPolicy.SP15.Norman-Major,Kris

This course examines the theoretical and philosophical approaches used to systematically examine the public policy process. Because no single theory or model can adequately describe the complexities of this process, the analytical frameworks and assumptions of the major approaches to policy analysis are emphasized, and emerging theories explored. In individual assignments, students are encouraged to examine policy issues and frameworks that relate to potential dissertation topics

DPA8995-KN.Dissertation V.F16.Norman-Major,Kristen

Independent work with chair/mentor writing up analysis and conclusions. Outcome is finished dissertation that will go to final defense

GPA8993-KN1.Dissertation III.Sp14.Norman-Major,Kristen

Independent work with chair/mentor to write chapter 3 (Methodology) and get IRB approval. Completion will then lead to Dissertation Proposal Defense (provided comprehensive exams have been passed)

GPA8992-KN.Dissertation II.Sp15.Norman-Major,Kristen

Independent work with chair/mentor to write chapters 1(Introduction) and 2 (Literature Review)

GPA8545-ABR.NationalPublicPolicyProccessAndIssues.SU15.Norman-Major,Kris

Washington DC has a special place when it comes to public administration. It is the center of the federal government but as important, it is the center of discussion around many public policy and administration issues. Every successful public administrator needs to have an understanding of how things in Washington DC work, how they can work effectively on national issues and deal with the federal government. This class will provide students with several unique experiences that can only be had in Washington DC. These experiences include talking with national leaders to discuss cutting-edge issues facing public administration, talking with persons who implement federal programs to understand the complexities of programs from the national level and understanding the federal policy-setting process by talking with actors in that process. In addition, this class will take advantage of a unique opportunity to talk about ethical issues facing public administrators that can only be had in Washington DC