Additional file 1 of Achievement of adequate nutrition contributes to maintaining the skeletal muscle area in patients with sepsis undergoing early mobilization: a retrospective observational study

Supplementary Material 1

Additional file 1 of Impact of the COVID-19 pandemic on prehospital and in-hospital treatment and outcomes of patients after out-of-hospital cardiac arrest: a Japanese multicenter cohort study

Supplementary Material 1: List of members of the SOS-KANTO 2017 Steering Committe

Additional file 1: of Subsequent shock deliveries are associated with increased favorable neurological outcomes in cardiac arrest patients who had initially non-shockable rhythms

Presents a list of institutional review boards. (PDF 77 kb

Genotype distributions.

<p>SS, severe sepsis/septic shock.</p

IRGM(+313) mRNA expression of whole blood with LPS challenge in healthy volunteers.

<p><i>P</i> = 0.019 with Mann-Whitney U test ((CC+CT) v TT).</p><p>RQ, relative quantification; ΔRQ, (post-stimulation)-(pre-stimulation with LPS).</p

Baseline characteristics of the study population.

<p><i>P</i> values were calculated with Student’s t-test* and Fisher’s exact test**. SS, severe sepsis/septic shock; ICU, intensive care unit; SOFA, sequential organ failure assessment; APACHE II, the acute physiology and chronic health evaluation; ICH, intracerebral hemorrhage; CI, cerebral infarction; CPAOA, cardiopulmonary arrest on arrival; SD, standard deviation.</p

Tests of association between IRGM(+313) genotype and severe sepsis death in the combined cohort.

<p><i>P</i> values were calculated with correlation/trend test.</p

Comparison of mortality between different genotype categories for SNP at IRGM(+313) (rs10065172).

<p>(a) The discovery cohort (<i>P</i> = 0.043, recessive model of the correlation/trend test; TT v (CC+CT) in the 125 SS patients). (b) The multi-center validation cohort (<i>P</i> = 0.037, recessive model the correlation/trend test; TT v (CC+CT) in the 271 SS patients). (c) The combined cohort (<i>P</i> = 0.004, recessive model the correlation/trend test; TT v (CC+CT) in the 396 SS patients). SS, severe sepsis/septic shock.</p