Synthesis and functionalization of 92S bioactive glasses for drug delivery system

<p>A new glass formulation, with the molar composition 92% SiO₂– 6 % CaO – 2% P₂O₅ was synthesized using the sol-gel process, for applications as biomaterial in orthopaedic or maxillo facial surgery. Pellets, made of glass powder, were uniaxially compacted and soaked  in Simulated Body Fluid (SBF) for up to 7 days at 37°C to evaluate glass bioactivity. Ionic exchanges  at the interface glass-SBF were evaluated by studying evolutions of calcium, phosphorus and  silicon concentrations in SBF using ICP-OES. Changes in glass surface, and the formation of crystalline phases were analyzed using XRD, SEM, EDS and FTIR methods. In the pharmaceutical field, these materials are particularly interesting for the synthesis of drugs for controlled release. </p

Synthesis of mesoporous silica hollow microspheres with controlled structural and optical properties using droplet-based microfluidics

<div>Thisstudyfocusesonthedevelopmentofanoriginaltemplate-freemethodforthesynthesisandcharacterizationofhighlymonodisperseandmesoporoushollowsilicamicrospherescontaininghighlyorderednanometer-scaleporesofcontrollablesize.</div><div>Fabricationofsuchmicrosystemsisofafundamentalandpracticalinterest,sincetheycanbeusedforcontrolleddrugdelivery,cellsencapsulationandculture,catalysis,biosensors,bio-materialsandtissue-engineering,etc.</div

Preparation of Mesoporous and monodisperse microdrops of bioglass through microfluidic chip

<p>The sol-gel method, with use of specific surfactants, is a preferred approach to generating a controlled porosity material of high specific surface. The development of microfluidics and the development of new manufacturing technologies for miniaturized devices can perform complex operations (synthesis, mixing, analysis ...) across the nanolitre.</p

Evaluation de la bioactivité d’un verre synthétisé par voie sol-gel

<p>D’un point de vue structural, on peut définir un verre comme « un solide non cristallin ». </p> <p>Certains verres se comportent comme des matériaux totalement inertes, d’autres sont biodégradables et d’autres enfin ont présentés une adaptation osseuse très satisfaisante. Ce dernier type particulier de verre; contenant de la silice, du calcium et des phosphates est appelé bioverre ou verre bioactif : il a la propriété de se lier intimement à l’os et de mieux s’adapter aux tissus que les biomatériaux habituellement utilisés.</p><p><br></p

Microfluidic-assisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules

<div>The fabrication of mesoporous silica microcapsules with a highly controlled particle size ranging in the micrometer size presents a major challenge in many academic and industrial research areas, such as for the developement of smart drug delivery systems with a well controlled loading and release of bioactive molecules...</div