3,369 research outputs found

    Channeled scablands of eastern Washington: the geologic story of the Spokane flood

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    This booklet describes the formation of the Channeled Scablands by a series of glacial floods. It includes photographs of formations formed by the activity described in the text. This work was originally published in 1947 by the Government Printing Office for the Department of the Interior with SuDoc number (I 19.2:W 27/6/974).https://dc.ewu.edu/spc_pubs/1005/thumbnail.jp

    Quantification of Uncertainty in the Measurement of Magnetic Fields in Clusters of Galaxies

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    We assess the principal statistical and physical uncertainties associated with the determination of magnetic field strengths in clusters of galaxies from measurements of Faraday rotation (FR) and Compton-synchrotron emissions. In the former case a basic limitation is noted, that the relative uncertainty in the estimation of the mean-squared FR will generally be at least one third. Even greater uncertainty stems from the crucial dependence of the Faraday-deduced field on the coherence length scale characterizing its random orientation; we further elaborate this dependence, and argue that previous estimates of the field are likely to be too high by a factor of a few. Lack of detailed spatial information on the radio emission--and the recently deduced nonthermal X-ray emission in four clusters--has led to an underestimation of the mean value of the field in cluster cores. We conclude therefore that it is premature to draw definite quantitative conclusions from the previously-claimed seemingly-discrepant values of the field determined by these two methods.Comment: 31 pages including 3 figures; accepted for publication in the Astrophysical Journal as paper #5497

    G Protein Coupled Receptors in Embryonic Stem Cells: A Role for Gs-Alpha Signaling

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    Background: Identification of receptor mediated signaling pathways in embryonic stem (ES) cells is needed to facilitate strategies for cell replacement using ES cells. One large receptor family, largely uninvestigated in ES cells, is G protein coupled receptors (GPCRs). An important role for these receptors in embryonic development has been described, but little is known about GPCR expression in ES cells. Methodology/Principal Findings: We have examined the expression profile of 343 different GPCRs in mouse ES cells demonstrating for the first time that a large number of GPCRs are expressed in undifferentiated and differentiating ES cells, and in many cases at high levels. To begin to define a role for GPCR signaling in ES cells, the impact of activating Gs-alpha, one of the major alpha subunits that couples to GPCRs, was investigated. Gs-alpha activation resulted in larger embryoid bodies (EBs), due, in part, to increased cell proliferation and prevented the time-related decline in expression of transcription factors important for maintaining ES cell pluripotency. Significance/Conclusions: These studies suggest that Gs-alpha signaling contributes to ES cell proliferation and pluripotency and provide a framework for further investigation of GPCRs in ES cells

    Evaluation of a Surface Exploration Traverse Analysis and Navigation Tool

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    SEXTANT is an extravehicular activity (EVA) mission planner tool developed in MATLAB, which computes the most efficient path between waypoints across a planetary surface. The traverse efficiency can be optimized around path distance, time, or explorer energy consumption. The user can select waypoints and the time spent at each, and can visualize a 3D map of the optimal path. Once the optimal path is generated, the thermal load on suited astronauts or solar power generation of rovers is displayed, along with the total traverse time and distance traveled. A field study was conducted at the Mars Desert Research Station (MDRS) in Utah to see if there was a statistical difference between the SEXTANT-determined energy consumption, time, or distance of EVA traverses and the actual output values. Actual traverse time was significantly longer than SEXTANT-predicted EVA traverse time (n=6, p<0.01), traverse distance was not significantly different than SEXTANT-predicted distance, and explorer energy consumption was significantly greater than SEXTANT-predicted energy consumption (n=5, p<0.01). A second study was done to see if mission re-planning, or contingency planning, was faster and less work when using SEXTANT in the habitat or in the field using an iPad. Time and workload measurements were collected for each subject under both conditions. Contingency planning in the habitat was not significantly different than contingency planning in the field. There was no significant workload difference when contingency planning in either location, however there was a trend that suggested contingency planning was faster in the habitat (n=3, p=0.07). Every subject commented that it was a hassle to carry the mission planner in the field and it was difficult to see the screen in the sunlight. To determine if gloves were a factor in the difference between mission re-planning time, subjects were asked to plan a contingency indoors with and without gloves. Performance and workload were not significantly different when re-planning with and without the gloves. The SEXTANT mission planner will continue to be improved according to the results and the recommendations of subjects in this study.United States. National Aeronautics and Space Administration (NASA Astrobiology Institute)Massachusetts Space Grant Consortiu

    Changes in recreational behaviors of outdoor enthusiasts during the COVID-19 pandemic: analysis across urban and rural communities

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    The COVID-19 pandemic presents not only a global health crisis but has also disrupted the daily lives of people around the world. From a leisure perspective, urban outdoor enthusiasts are one group particularly impacted by the pandemic and the subsequent institutional response. Stay-at-home orders and physical distancing recommendations serve as potential inhibitors to outdoor recreation activities central to the lifestyles and wellbeing of outdoor enthusiasts. In urban areas, where these orders and recommendations are most restrictive, the potential impacts on recreation behavior are most consequential. This study provides an empirical analysis of the COVID-19 pandemic’s impact on the recreational behaviors of outdoor enthusiasts across urban and rural communities. Results suggest that the frequency of outdoor recreation participation, distance travelled to participate in outdoor recreation and distance travelled beyond roads during outdoor recreation have declined significantly more among outdoor enthusiasts residing in urban areas than urban clusters or rural areas

    Dynamics Among Borderline Personality and Anxiety Features in Psychotherapy Outpatients: An Exploration of Nomothetic and Idiographic Patterns

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    Borderline personality disorder (BPD) involves instability in self-concept, emotions, and behavior. However, the dynamic, longitudinal relations among BPD symptoms and between these symptoms and other problematic emotional experiences are poorly understood. It is also unclear whether these dynamics are the same across persons (including across diagnostic boundaries), specific to individuals with BPD, or idiographic. The current study uses ecological momentary assessment and Group Iterative Multiple Model Estimation (GIMME), a novel, data-driven approach to identifying dynamic patterns in time-series data at group, subgroup, and individual levels, to investigate the dynamic connections among select features of BPD (anger, impulsivity, and identity disturbance) and anxiety-related experiences. Forty-two psychiatric outpatients diagnosed with BPD (n = 27) or with an anxiety disorder, but not BPD (n = 15) rated their anger, identity disturbance, impulsivity, anxiety, stress, and calmness states six times per day for 21 days, providing a total of 4,699 surveys. Only one dynamic link between symptoms was identified that applied at the group level, and GIMME did not reveal stable subgroups of individuals with distinct symptom dynamics. Instead, these dynamics differed from individual to individual. These results suggest that connections among these BPD and anxiety symptoms do not depend on diagnosis and are somewhat idiographic. Case examples are used to illustrate the clinical utility of within-person symptom models as a supplement to traditional diagnostic information

    Structural equation modeling of food craving across the menstrual cycle T using behavioral, neuroendocrine, and metabolic factors

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    Objective: To identify associations between circulating endocannabinoids and craving during the luteal phase of the menstrual cycle. This report is a secondary analysis of a trial registered in clinicaltrials.gov as NCT01407692. Methods: Seventeen premenopausal women were studied during the follicular and luteal phases of their menstrual cycle. Previously we had reported fasting plasma estradiol, progesterone, leptin associations with luteal phase cravings for carbohydrate, fat, sweet-rich foods, and eating behavior. Here, we measured fasting plasma endocannabinoids (ECs) endocannabinoid-like substances (ECLs), and postprandial metabolic responses to a mixed meal challenge. Structural equation modeling was used to evaluate relationships between measured variables and cravings. Results: Oleoylethanolamide (OEA) and postprandial lipids were inversely associated with craving sweet-rich foods, while progesterone was positively associated (RMSEA = 0.041, χ2 p: 0.416 i.e. hypothetical and physiological models not different). OEA, progesterone and disinhibition were positively associated with craving carbohydrates (RMSEA: \u3c 0.001, χ2 p: 0.919). ECs and ECLs combined were stronger predictors of craving than clinical metabolic parameters, ECs only, satiety hormones or gonadocorticoids. Conclusions: Our theoretical model suggests that ECs and ECLs influence craving. Since these metabolites can be modulated via dietary fat intake, they could be potential targets to alter menstrual cycle cravings

    Phytotechnologies - Preventing Exposures, Improving Public Health

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    Phytotechnologies Have Potential to Reduce the Amount or Toxicity of Deleterious Chemicals and Agents, and Thereby, Can Reduce Human Exposures to Hazardous Substances. as Such, Phytotechnologies Are Tools for Primary Prevention in Public Health. Recent Research Demonstrates Phytotechnologies Can Be Uniquely Tailored for Effective Exposure Prevention in a Variety of Applications. in Addition to Exposure Prevention, Plants Can Be Used as Sensors to Identify Environmental Contamination and Potential Exposures. in This Paper, We Have Presented Applications and Research Developments in a Framework to Illustrate How Phytotechnologies Can Meet Basic Public Health Needs for Access to Clean Water, Air, and Food. Because Communities Can Often Integrate Plant-Based Technologies at Minimal Cost and with Low Infrastructure Needs, the Use of These Technologies Can Be Applied Broadly to Minimize Potential Contaminant Exposure and Improve Environmental Quality. These Natural Treatment Systems Also Provide Valuable Ecosystem Services to Communities and Society. in the Future, Integrating and Coordinating Phytotechnology Activities with Public Health Research Will Allow Technology Development Focused on Prevention of Environmental Exposures to Toxic Compounds. Hence, Phytotechnologies May Provide Sustainable Solutions to Environmental Exposure Challenges, Improving Public Health and Potentially Reducing the Burden of Disease. © 2013 Copyright Taylor and Francis Group, LLC
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