Receiver Operating Characteristic curves in the different prognostic models.

<p>(A) SAPS II and SAPS II-CNIV. (B) SAPS 3 and SAPS 3-CNIV.</p

Clinical application of SAPS 3-CNIV: Death probability according to customized scores.

<p>Clinical application of SAPS 3-CNIV: Death probability according to customized scores.</p

Patient characteristics.

<p>Values are expressed as mean (standard deviation), unless otherwise stated.</p><p>SD: Standard deviation; COPD: chronic obstructive pulmonary disease; ICU: Intensive care unit; ImCU: Intermediate care unit; BP: Blood pressure; C-RP: C-reactive protein</p><p>*Immunosuppression as described in SAPS 3: Use of chemotherapy, radiotherapy, immunosuppressive drugs or corticosteroids in the last 6 months</p><p>Patient characteristics.</p

Indications for NIV and mortality.

<p>Values are expressed as mean (standard deviation), unless otherwise stated.</p><p>DNR: Do not resuscitate; SAPS Simplified acute physiological score; SMR: Standardized mortality ratio; COPD: Chronic obstructive pulmonary disease; ARF: Acute respiratory failure.</p><p>*Hypoxemic ARF group includes lower tract respiratory infection (n120), ALI/ARDS (n15) and Pulmonary Embolism (n2)</p><p>**Data are expressed as median and IQR due to small subgroup size.</p><p>^†p of comparison between subgroups was calculated with chi-square and Kruskal Wallis tests.</p><p>Indications for NIV and mortality.</p

Univariate analysis of new variables for NIV mortality prediction.

<p>Values are expressed as mean (standard deviation), unless otherwise stated.</p><p>*COPD/hypoxemic ARF/APE/Neuromuscular disease</p><p>^†p of comparison between subgroups was calculated with t-Student and chi square tests</p><p>Univariate analysis of new variables for NIV mortality prediction.</p

Logistic regression and score customization for SAPS II.

<p>*Immunosuppression as described in SAPS 3: Use of chemotherapy, radiotherapy, immunosuppressive drugs or corticosteroids in the last 6 months</p><p>Logistic regression and score customization for SAPS II.</p

Logistic regression and score customization for SAPS 3.

<p>Logistic regression and score customization for SAPS 3.</p

Performance of the scores.

<p>SMR: Standardized mortality ratio. O/E: Observed/expected. NA: Not applicable</p><p>Performance of the scores.</p

Clinical application of SAPS II-CNIV: Death probability according to customized scores.

<p>Clinical application of SAPS II-CNIV: Death probability according to customized scores.</p