Seroma formation after modified radical mastectomy: analysing risk factors and incidence

Background: Breast cancer is a prevalent form that affects women and is a leading cause of death among women. The development of seroma is a frequent complication that can arise after breast cancer surgery, and its underlying mechanisms are still not fully understood. Consequently, data was collected to analyze the occurrence and factors that contribute to the development of seroma in patients. We aimed to enhance our comprehension and ultimately discover methods to mitigate it. Methods: A prospective group research study was conducted on a sample of 86 female patients who underwent mastectomy from August 2020 to August 2023. This study was carried out as part of the senior residency program at Nalanda Medical College and Hospital in Patna, Bihar, India. Patients who develop seroma within four weeks of surgery are usually recommended to undergo, specifically ultrasonography, and radiological evaluation to determine the size. Results: 27 out of 86 patients (31%) were found to have seroma. Several factors are closely linked to the development of seroma. Factors that may contribute to increased risk The minimum age at which seroma production occurs following MRM ≥56 or older, having a BMI of 26.50 or higher, a tumour measuring 4 cm or larger undergoing the removal of more than 12 lymph nodes, and having a level 3 axillary dissection. Conclusions: After surgery, a certain group of people in the study experienced seroma formation within four weeks. These individuals had undergone MRM. Age, BMI, tumour size, level 3 axillary dissection, the removal of more than 12 lymph nodes during surgery, and the occurrence of seroma after MRM were found to be positively correlated. There was no observed connection between seroma production and a range of factors, such as neoadjuvant chemotherapy, the timing of drain removal, shoulder workouts, and the use of breast bandages

Intestinal obstruction caused by tuberculosis: unmasking a silent risk

Background: Intestinal tuberculosis (TB) remains a global health challenge, especially in regions with a high TB prevalence. This manifestation, distinct from pulmonary TB, involves the gastrointestinal tract, often leading to intestinal obstruction. The study addresses the insidious nature of the disease, emphasizing the urgency for timely diagnosis and intervention. Recognizing the multifaceted impact of TB on various organs, the study explores the pathophysiology, clinical presentation, and diagnostic complexities of intestinal TB. Methods: This study was conducted at Nalanda medical college and hospital in Patna, Bihar, India, the retrospective study spans three years focusing on 127 patients with intestinal obstruction due to TB. Inclusion criteria prioritized histopathological confirmation of TB, ensuring cohort accuracy. The study employed preliminary investigations, including hemogram, chest X-ray, abdominal X-ray, ultrasonogram, sputum examination, and Mantoux test and CECT whole abdomen. Clinical presentations were systematically analyzed, guiding tailored management protocols based on the mode of presentation. Results: Demographically, the study identified TB as the cause in 127 cases, with a balanced gender distribution and a peak incidence in the 21-30 years age group. Presentations varied, predominantly with acute symptoms. Common complaints included abdominal pain, vomiting, constipation, and distension. Surgical intervention within 24 hours was crucial in 61.1% of cases. Intraoperatively, findings comprised mesenteric thickening, lymph nodal enlargement, and adhesions. Adhesionolysis was the primary procedure. Postoperative complications, mainly wound infections, were noted but had a limited impact on mortality. Conclusions: This study reveals TB as a significant contributor to intestinal obstruction, emphasizing challenges in early diagnosis. Adhesionolysis emerges as a key operative procedure, underscoring the need for surgical flexibility. Postoperative complications, while notable, have minimal impact on mortality

Comment on the Generation Number in Orbifold Compactifications

There has been some confusion concerning the number of $(1,1)$-forms in orbifold compactifications of the heterotic string in numerous publications. In this note we point out the relevance of the underlying torus lattice on this number. We answer the question when different lattices mimic the same physics and when this is not the case. As a byproduct we classify all symmetric $Z_N$-orbifolds with $(2,2)$ world sheet supersymmetry obtaining also some new ones.Comment: 28 pages, 9 figures not included, available in postscript at reques

20 Years of Progress in Intestinal Parasitic Diseases Research

Since 1968 investigators from U.S. Naval Medical Research Unit No. 2 Detachment (NAMRU-2) and the National Institute of Health Research and Development (NIHRD) have conducted parasitological/biomedical surveys in every major island in the Indonesian archipelago. Even smaller islands such as Nasi and Beras off of Sumatra and Beeuw off of Irian Jaya are represented in these studies. These activities were aimed to update and provide new information on the prevalence and distribution of intestinal parasites as well as other infectious agents. These surveys were done in collaboration with the Directorate General of Communicable Disease Control and Environmental Health (CDC&EH), universities and other health institutions such as the Indonesian Armed Forces Health Services, Provincial Health Services, and others. Stool specimens, blood smears, and venous blood examined in these studies showed that most of the population surveyed were infected with one to 7 different species of parasites. Between 50% to 95% of the population had multiple infections

Equation of State for Neutralino Star as a Form of Cold Dark Matter

In order to study the structure of neutralino star and dark galaxy, we consider dynamical interactions due to boson-exchange in the neutralino matter. Taking into account interactions of neutralinos with bosons, we derive the equation of state (EOS) of neutralino stars in terms of the relativistic mean field approach. Then we apply the resulting EOS to investigate properties of the neutralino star such as its density profile and mass limit. For example, if the neutralino mass is around 1 TeV, the Oppenheimer mass limit of the neutralino star is obtained as $6.06\times 10^{-7}M_\odot$, and the corresponding radius is about 7.8 mm. Actually, due to an increasing annihilation rate as indicated by our calculation, this dense state can never be realized in practice. Our results also show that the low density neutralino star may be a possible aggregation of the cold dark matter.Comment: 5 pages, 5 figures; v2: matches published versio

Alfvenic Heating of Protostellar Accretion Disks

We investigate the effects of heating generated by damping of Alfven waves on protostellar accretion disks. Two mechanisms of damping are investigated, nonlinear and turbulent, which were previously studied in stellar winds (Jatenco-Pereira & Opher 1989a, b). For the nominal values studied, f=delta v/v_{A}=0.002 and F=varpi/Omega_{i}=0.1, where delta v, v_{A} and varpi are the amplitude, velocity and average frequency of the Alfven wave, respectively, and Omega_{i} is the ion cyclotron frequency, we find that viscous heating is more important than Alfven heating for small radii. When the radius is greater than 0.5 AU, Alfvenic heating is more important than viscous heating. Thus, even for the relatively small value of f=0.002, Alfvenic heating can be an important source of energy for ionizing protostellar disks, enabling angular momentum transport to occur by the Balbus-Hawley instability.Comment: 21 pages, 9 figures. Accepted for publication in Ap

Exactly stable non-BPS spinors in heterotic string theory on tori

Considering SO(32) heterotic string theory compactified on a torus of dimension 4 and less, stability of non-supersymmetric states is studied. A non-supersymmetric state with robust stability is constructed, and its exact stability is proven in a large region of moduli space against all the possible decay mechanisms allowed by charge conservation. Using various T-duality transform matrices, we translate various selection rules about conserved charges into simpler problems resembling partition and parity of integers. For heterotic string on T^4, we give a complete list of BPS atoms with elementary excitations, and we study BPS and non-BPS molecules with various binding energies. Using string-string duality, the results are interpreted in terms of Dirichlet-branes in type IIA string theory compactified on an orbifold limit of a K3 surface.Comment: 47 pages, 14 figures, LaTe

Duality in Non-Trivially Compactified Heterotic Strings

We study the implications of duality symmetry on the analyticity properties of the partition function as it depends upon the compactification length. In order to obtain non-trivial compactifications, we give a physical prescription to get the Helmholtz free energy for any heterotic string supersymmetric or not. After proving that the free energy is always invariant under the duality transformation $R\rightarrow \alpha^{'}/(4R)$ and getting the zero temperature theory whose partition function corresponds to the Helmholtz potential, we show that the self-dual point $R_{0}=\sqrt{\alpha^{'}}/2$ is a generic singularity as the Hagedorn one. The main difference between these two critical compactification radii is that the term producing the singularity at the self-dual point is finite for any $R \neq R_{0}$. We see that this behavior at $R_{0}$ actually implies a loss of degrees of freedom below that point.Comment: (Preprint No. FTUAM-92/12) 17 page

Polarization and magnetization dynamics of a field-driven multiferroic structure

We consider a multiferroic chain with a linear magnetoelectric coupling induced by the electrostatic screening at the ferroelectric/ferromagnet interface. We study theoretically the dynamic ferroelectric and magnetic response to external magnetic and electric fields by utilizing an approach based on coupled Landau- Khalatnikov and finite-temperature Landau-Lifshitz-Gilbert equations. Additionally, we compare with Monte Carlo calculations. It is demonstrated that for material parameters corresponding to BaTiO3/Fe the polarization and the magnetization are controllable by external magnetic and electric fields respectively

Konishi anomaly approach to gravitational F-terms

We study gravitational corrections to the effective superpotential in theories with a single adjoint chiral multiplet, using the generalized Konishi anomaly and the gravitationally deformed chiral ring. We show that the genus one correction to the loop equation in the corresponding matrix model agrees with the gravitational corrected anomaly equations in the gauge theory. An important ingrediant in the proof is the lack of factorization of chiral gauge invariant operators in presence of a supergravity background. We also find a genus zero gravitational correction to the superpotential, which can be removed by a field redefinition.Comment: 28 pages, uses JHEP3.cl