CHANGES OF CARDIOVASCULAR STABILITY IN CORONARY PATIENTS AND HEALTHY CONTROLS OVER AN INDIVIDUAL YEAR

To determine the influence of an individual year cycle (IYC) lasting from one birthday to another, on the clinical, laboratory and physiological values, we have studies case histories of 330 men with acute coronary pathology and also examined 146 men with Coronary Heart Disease admitted for CABG. 35 almost healthy young men were also examined during a year in different seasons.We have found out that the number of patients developing MI in the XII month of the IYC, was reliably higher that the value for IV-VI months and almost twice as high as the number for the VI month. The severity of MI developing in the XII and I months of the IYC surpassed such in MI developing in other periods of the IYC. In the IV trimester of the IYC (X-XII months) the patients showed a relatively low number of T-cells, the highest cortisol concentration in the saliva, in the III and IV months – T-supressors; in the IV trimester coronary patients showed much less thyroxin, tri-iodothyronin and cortisol than in the I trimester. Blood values in the II trimester of the IYC were consistent with a better prognosis.Healthy young men showed stressed adaptation mechanisms in the IV trimester of the IYC: increased personal alertness (the index of regulatory systems stressing was calculated from a mathematical analysis of heart rate), higher incidence of hypertension, decreased ability to work and immunity. The values in the II trimester were more favorable.The data enable us to draw a conclusion about the universal nature of IYC changes of adaptive parameters of cardiovascular and endocrine systems, which is crucial for preventive cardiology

Sputtered-deposited thin brass films in a modified glow discharge Grimm-type source

Modification of the non-assisted gas flow-line across the target surface in a Grimm-type glow discharge source is described. The new flow–line permits the gas to flow through a cylindrical annular space ending with a disc-space annular gap, facing the target surface. This configuration would cause directed jet assisted gas flow rays to impinge on infinite points across the cathode surface. Improvement has been achieved in the V-I characteristics where $\Delta V$/$\Delta I$ increases from 1.8 to 3.5 V/mA. The sputtering as well as simultaneous deposition rates, have been increased by a factor of 16 and 17 respectively. These roll over with increasing sputtering time, their maximum values at a characteristic time, toc of 21 min. The toc value was constant for different operating parameters provided that the source geometry assembly is kept fixed. The presence of a glass substrate in the anode cavity has, apparently, no effect on the obtained data. Improvements have also been achieved in the crater profile, characterized by an approximately flat crater bottom with nearly vertical walls, and less re-deposited particles on the crater depth and edge. Fixing the distance Z of the substrate from target surface, along the cell axis, and varying the deposition time from 1 to 30 min, a sequence of changes in the deposited film were observed by X-ray diffraction and energy dispersion X-ray (EDX). These changes start with an amorphous structure, followed by the appearance of Cu and Zn crystallites and a probable deposition of Cu5Zn8 clusters. The profile of the number of sputtered particles at different Z values is characterized by a number of peaks and troughs. This behavior has been explained by the occurrence of local cluster-dissociation and formation, by different collision processes. The improvements achieved by the application of the present jet assisted gas flow can be of value in the analytical application of this type of glow discharge