PAR-1 mediated synchronized non-periodical [Ca²⁺]_i oscillations in HRMCs in response to TFLLR-NH₂application

Representative video illustrating synchronized non-periodical calcium oscillations in mesangial cells mediated by PAR1 receptor activation after application of TFLLR-NH2 (4 µM) (Fluo-8 fluorescence; compressed video 15 fps; Δframe time 2.5 sec). Total (non-compressed) recording time is 20 minutes.</p

PAR-1 mediated synchronized non-periodical [Ca²⁺]_i oscillations in HRMCs in response to thrombinapplication

Representative video illustrating synchronized non-periodical calcium oscillations in mesangial cells mediated by application of thrombin (5 µM) (Fluo-8 fluorescence; compressed video 15 fps; Δframe time 2.5 sec). Total (non-compressed) recording time is 20 minutes.</p

Intracellular Ca²⁺oscillations in HRMCs in response to thrombin application in the presence of PAR1 antagonist RWJ 56110

Representative video illustrating Intracellular Ca2+ signaling in HRMCs in response to thrombin (5 µM) application in the presence of PAR1 antagonist RWJ 56110 (10µM) (Fluo-8 fluorescence; compressed video 15 fps; Δframe time 2.5 sec). Total (non-compressed) recording time is 14 minutes.</p