Formulations of coenzyme Q.sub.10 for intravenous use

The present invention comprises a stable and non-toxic coenzyme Q.sub.10 formulation suitable for intravenous administration to an animal to produce clinically effective blood levels of coenzyme Q.sub.10. Clinically effective blood levels of coenzyme Q.sub.10 are generally agreed to be between about 2 ug/ml and about 4 ug/ml. The formulation consists essentially of a clinically accepted fatty emulsion having an oil phase and coenzyme Q.sub.10 dissolved in the oil phase. The formulation preferably contains coenzyme Q.sub.10 at a level between about 7.5 ug/ml and about 30 ug/ml. The clinically accepted fatty emulsion comprises at least one vegetable oil, preferably corn oil, peanut oil, safflower oil, olive oil or soybean oil.Board of Regents, University of Texas Syste

Study of Lively Elderly from Dental Aspects (2) : DMF, Number of Molar Tooth, Periodontal Condition and Mobility of Tooth

Previous our study had shown that number of teeth presented were closely related to liveliness in an elderly. In order to clarify the relationship between wellness of oral function and liveliness in an elderly in detail, especially from the view point of the quality of teeth presented, we studied number of molar tooth presented. DMF, periodontal conditions, and mobility of teeth in the lively elderly examined previously. Periodontal conditions were estimated with gingival index, bleeding index, and probing depth. The lively elderly examined were selected on the basis of the following items: 1) People over 65 and less than 80 years old living in Kasuga-shi at present. 2) People without any subjective and objective diseases. 3) People with high social activities. 4) People recommended as being lively physically and mentally by the district senile clubs. The number, sex, and mean age of the subjects were 39 ( male 20 , female 19 ) and 73.3 years old. The data were compared with the authorized Japanese average values matched age of the subjects reported by Ministry of Health and Welfare. Japan. Mean number of molar tooth presented in the lively elderly was 2.7+-2.6, which was about double compared with the one of the Japanese average. Mean number of decayed(D), missing(M), treated(F), and DMF teeth per person were 0.6+1.4, 15.3+-9.6, 6.0+-5.7, and 19.7+-8.3 in the lively elderly, respectively. These data indicated significantly better dental condition with higher treatment rate compared with the Japanese average. Mean gingival and bleeding index were 1.6 and 47%, respectively, which indicate existence of gum inflammation spreaded moderately. However, quite few destructive periodontal disease with deep pocket over 4 mm was found. These data which indicate satisfying conditions of teeth periodontologically were supported by the data of low ratio(7.6%) of moving teeth/teeth presented. These results suggested that well dental state qualitatively were related to liveliness in an elderly

生き生き老人健康調査における歯科学的考察（第2報） : DMF、大臼歯の数、歯周組織の状況、及び歯牙の動揺度について

Previous our study had shown that number of teeth presented were closely related to liveliness in an elderly. In order to clarify the relationship between wellness of oral function and liveliness in an elderly in detail, especially from the view point of the quality of teeth presented, we studied number of molar tooth presented. DMF, periodontal conditions, and mobility of teeth in the lively elderly examined previously. Periodontal conditions were estimated with gingival index, bleeding index, and probing depth. The lively elderly examined were selected on the basis of the following items: 1) People over 65 and less than 80 years old living in Kasuga-shi at present. 2) People without any subjective and objective diseases. 3) People with high social activities. 4) People recommended as being lively physically and mentally by the district senile clubs. The number, sex, and mean age of the subjects were 39 ( male 20 , female 19 ) and 73.3 years old. The data were compared with the authorized Japanese average values matched age of the subjects reported by Ministry of Health and Welfare. Japan. Mean number of molar tooth presented in the lively elderly was 2.7+-2.6, which was about double compared with the one of the Japanese average. Mean number of decayed(D), missing(M), treated(F), and DMF teeth per person were 0.6+1.4, 15.3+-9.6, 6.0+-5.7, and 19.7+-8.3 in the lively elderly, respectively. These data indicated significantly better dental condition with higher treatment rate compared with the Japanese average. Mean gingival and bleeding index were 1.6 and 47%, respectively, which indicate existence of gum inflammation spreaded moderately. However, quite few destructive periodontal disease with deep pocket over 4 mm was found. These data which indicate satisfying conditions of teeth periodontologically were supported by the data of low ratio(7.6%) of moving teeth/teeth presented. These results suggested that well dental state qualitatively were related to liveliness in an elderly

Study od Lively Elderly from Dental Aspects

The present study was designed to elucidate the relationship between lively elderly and dental status including biting force. The lively elderly examined were selected on the basis of the following items: 1) People over 65 and less than 80 years old living in Kasuga-shi at present. 2) People without any subjective and objective diseases. 3) People with high social activities. 4) People recommended as being lively physically and mentally by the district senile clubs. The number, sex and mean age of the subjects were 39 (male 20, female 19) and 73.3 years old. Edentulous rate, number of present and intact teeth, and maximum biting force were examined in the study and compared with the authorized Japanese average value of the items matched age of the subjects (1981) reported by Ministry of Health and Welfare, Japan. The results obtained are as follows: 1. The edentulous subjects rate was 20.5% in the lively elderly, and almost half (p<0.01) of the Japanese average (39.1%). 2. Number of the present teeth per person was 13.0+-9.3 (mean+-S.D.) in the lively elderly and about double (p<0.001) of the Japanese average (6.8). 3. Number of intact teeth per person was 5.8+-6.6 in the lively elderly and about double (p<0.05) of the Japanese average (2.8). 4. Significant correlations were found between the maximum biting force and the present (r=0.599, p<0.01) and the intact (r=0.431, p<0.05) teeth. These results shows that numbers of both present and intact teeth were closely related to liveliness in the elderly. Therefore, it was suggested that prevention of dental diseases plays an important role on the increase of lively elderly in the society

A Primitive Study on Relationships between Dental Function and Physical Function : Physique of the Elderly Males

In this paper, the relationships between physical function or physique, and dental function variables were investigated. Twenty two elderly volunteers(mean age=73.4; SD=3.54 years) participated as subjects in this quasi-experimental survey. The code names in this article represent the measurement as follows. DMFT(= Total number of decayed(D), missing(M), and treated(F) teeth), MT(=Number of missing teeth). GI(=Index for degree of gingival inflammation by visual inspection), PD(mm: -Depth of gingival sulcus or periodontal pocket examined with a dental probe), RPD(%: = Rate of number of teeth with periodontal pocket over 4mm depth per teeth presented), BI(%: = Index for degree of gingival inflammation determined by bleeding from gingival sulcus at touching with a dental probe), MI(= Index for degree of mobility of teeth), BF(R:L)(kg:= Maximum biting force in each side), VSAL(ml/min: - Volume of saliva secreted per minute) and PLQ(-Index for degree of plaque retention on teeth, which reflects individual daily food intake style and cleaning habits and technic of mouth). Concerning gum tissue, the following positive correlationships with physical function variables were observed DMFT and blinded balance in place; GI and standing height; BI and standing height; MI and blinded balance; PLQ and blinded balance. Many investigations have previously suggested that a correlations between grip strength and dental indexes existed, and it would seem to follow that the correlation with dental indexes also exists for sense of balance concerning the elderly

歯科機能の老化と体格・体力の関連度について : 男子高齢者の場合

In this paper, the relationships between physical function or physique, and dental function variables were investigated. Twenty two elderly volunteers(mean age=73.4; SD=3.54 years) participated as subjects in this quasi-experimental survey. The code names in this article represent the measurement as follows. DMFT(= Total number of decayed(D), missing(M), and treated(F) teeth), MT(=Number of missing teeth). GI(=Index for degree of gingival inflammation by visual inspection), PD(mm: -Depth of gingival sulcus or periodontal pocket examined with a dental probe), RPD(%: = Rate of number of teeth with periodontal pocket over 4mm depth per teeth presented), BI(%: = Index for degree of gingival inflammation determined by bleeding from gingival sulcus at touching with a dental probe), MI(= Index for degree of mobility of teeth), BF(R:L)(kg:= Maximum biting force in each side), VSAL(ml/min: - Volume of saliva secreted per minute) and PLQ(-Index for degree of plaque retention on teeth, which reflects individual daily food intake style and cleaning habits and technic of mouth). Concerning gum tissue, the following positive correlationships with physical function variables were observed DMFT and blinded balance in place; GI and standing height; BI and standing height; MI and blinded balance; PLQ and blinded balance. Many investigations have previously suggested that a correlations between grip strength and dental indexes existed, and it would seem to follow that the correlation with dental indexes also exists for sense of balance concerning the elderly

生き生き老人健康調査における歯科学的考察（第一報） : 無歯顎者率、残存歯数並びに健全歯数とその最大咬合力との関係

The present study was designed to elucidate the relationship between lively elderly and dental status including biting force. The lively elderly examined were selected on the basis of the following items: 1) People over 65 and less than 80 years old living in Kasuga-shi at present. 2) People without any subjective and objective diseases. 3) People with high social activities. 4) People recommended as being lively physically and mentally by the district senile clubs. The number, sex and mean age of the subjects were 39 (male 20, female 19) and 73.3 years old. Edentulous rate, number of present and intact teeth, and maximum biting force were examined in the study and compared with the authorized Japanese average value of the items matched age of the subjects (1981) reported by Ministry of Health and Welfare, Japan. The results obtained are as follows: 1. The edentulous subjects rate was 20.5% in the lively elderly, and almost half (p<0.01) of the Japanese average (39.1%). 2. Number of the present teeth per person was 13.0+-9.3 (mean+-S.D.) in the lively elderly and about double (p<0.001) of the Japanese average (6.8). 3. Number of intact teeth per person was 5.8+-6.6 in the lively elderly and about double (p<0.05) of the Japanese average (2.8). 4. Significant correlations were found between the maximum biting force and the present (r=0.599, p<0.01) and the intact (r=0.431, p<0.05) teeth. These results shows that numbers of both present and intact teeth were closely related to liveliness in the elderly. Therefore, it was suggested that prevention of dental diseases plays an important role on the increase of lively elderly in the society