Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

We present data showing that individual skeletal stem cell populations respond to nanoscale topography differently, and that seeding protocols can be optimised to enhance self-renewal allowing nanotopography to be used as a tool for the study of multipotency. Biochemical, transcriptomic and metabolomic protocols were used to investigate roles for mitogen activated protein kinases as a self-renewal / differentiation control switch and implicate control of cell cycle as being critical for maintenance of multipotency in prolonged culture. This has clear implications for production of large-numbers of high quality skeletal stem cells in vitro

The love of money is the root of all evil: Pay satisfaction and cpi as moderators

10.5464.AMBPP.2011.135.aAcademy of Management 2011 Annual Meeting - West Meets East: Enlightening. Balancing. Transcending, AOM 2011

The love of money is the root of all evil: Pay satisfaction and cpi as moderators

By incorporating pay satisfaction at Level 1 and Corruption Perceptions Index (CPI) at Level 2, we investigated the relationship between the love of money and self-reported corrupt intent among 6,382 managers in 31 geopolitical entities across six continents. Our significant cross-level three-way interaction effect showed that for managers with high pay satisfaction, the intensity (slope) of the love of money to corrupt intent relationship was almost identical in high or low CPI entities but the former had the lowest magnitude of corrupt intent, whereas the latter had the highest. For those with low pay satisfaction, the slope was the steepest in high CPI entities, but was flat in the low CPI entities and the difference between the two was significant