Additional file 1: of Clinical safety and efficacy of vitamin D3 analog ointment for treatment of obstructive meibomian gland dysfunction

Detailed data of the subjects at pre-, one months after and two months after treatment with Vit D3. (XLSX 18 kb

Relation of accommodative microfluctuation with dry eye symptoms in short tear break-up time dry eye

<div><p>Purpose</p><p>To investigate accommodative microfluctuations (AMFs) and visual function in short tear break-up time (BUT)-type dry eye (DE) and non-DE subjects.</p><p>Methods</p><p>This prospective comparative study included 48 volunteers with DE symptoms (mean age 34.8 ± 5.5 years, age range 25–42 years) and 73 without DE symptoms (mean age 30.6 ± 4.7 years, age range 25–42 years). The eyes were divided into two groups: (1) DE group with DE symptoms and BUT ≤ 5 s and (2) non-DE group without DE symptoms and BUT > 5 s. We excluded eyes with Schirmer score ≤ 5 mm and positive keratoconjunctival epithelial damage. Tear evaluation, AMF, and functional visual acuity (VA) examinations were performed. AMF parameters included total high-frequency component (HFC), HFC with low accommodation for the task of staring into the distance (HFC1), and HFC with high accommodation for deskwork (HFC2). Functional VA parameters included starting VA, functional VA, visual maintenance ratio, and blink frequency.</p><p>Results</p><p>A total of 33 and 34 eyes were categorized in the DE and non-DE groups, respectively. Mean blink frequency and HFC1 values were significantly higher in the DE group than they were in the non-DE group.</p><p>Conclusions</p><p>DEs with symptoms showed abnormal AMF and visual function, which may be associated with DE symptoms.</p></div

Functional visual acuity parameters for each group.

<p>(A) Starting and functional visual acuity, (B) visual maintenance ratio, and (C) blink frequency of study subjects.</p

Frequency scores of dry eye symptoms for each group.

<p>Frequency scores of dry eye symptoms for each group.</p

Randomized Controlled Study to Investigate the Effect of Topical Diquafosol Tetrasodium on Corneal Sensitivity in Short Tear Break-Up Time Dry Eye

<p><b>Article full text</b></p> <p><br></p> <p>The full text of this article can be found here<b>. </b><a href="https://link.springer.com/article/10.1007/s12325-018-0685-1">https://link.springer.com/article/10.1007/s12325-018-0685-1</a></p><p></p> <p><br></p> <p><b>Provide enhanced content for this article</b></p> <p><br></p> <p>If you are an author of this publication and would like to provide additional enhanced content for your article then please contact <a href="http://www.medengine.com/Redeem/”mailto:[email protected]”"><b>[email protected]</b></a>.</p> <p><br></p> <p>The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content.</p> <p><br></p> <p>Other enhanced features include, but are not limited to:</p> <p><br></p> <p>• Slide decks</p> <p>• Videos and animations</p> <p>• Audio abstracts</p> <p>• Audio slides</p><br

Prevalence of positive symptoms in dry eye (DE) and non-(DE) groups.

<p>Prevalence of positive symptoms in dry eye (DE) and non-(DE) groups.</p

Profile of tear functions in all subjects.

<p>Profile of tear functions in all subjects.</p

Power spectra for accommodative parameters of each group.

<p>High-frequency component (HFC) 1, between 0.0–0.75 diopter with low accommodation for staring into the distance task; HFC2, between -1.0 and -3.0 diopters with high accommodation for desk work; and total HFC, between 0.75 and -3.0 diopters.</p

Mechanism of dry eye symptom stimulation.

<p>Mechanism of dry eye symptom stimulation.</p

Strengths use as a secret of happiness: Another dimension of visually impaired individuals' psychological state

<div><p>It is well recognized that visual impairments (VI) worsen individuals’ mental condition. However, little is known about the positive aspects including subjective happiness, positive emotions, and strengths. Therefore, the purpose of this study was to investigate the positive aspects of persons with VI including their subjective happiness, positive emotions, and strengths use. Positive aspects of persons with VI were measured using the Subjective Happiness Scale (SHS), the Scale of Positive and Negative Experience-Balance (SPANE-B), and the Strengths Use Scale (SUS). A cross-sectional analysis was utilized to examine personal information in a Tokyo sample (N = 44). We used a simple regression analysis and found significant relationships between the SHS or SPANE-B and SUS; on the contrary, VI-related variables were not correlated with them. A multiple regression analysis confirmed that SUS was a significant factor associated with both the SHS and SPANE-B. Strengths use might be a possible protective factor from the negative effects of VI.</p></div