5,040 research outputs found
初級後半における物語創作活動
Oral PresentationConference Theme: Japanese Language Proficiency in Asia: Learners’ Sociolinguistic Competence and Diversity in Practice初級の後半になると、語彙や文法知識もかなり蓄積され、日本語で様々なことを理解・
表現する能力が備わってくるが、学習者によっては頭の中にある知識が発話や作文といっ
たアウトプットに結びついていないように見受けられるケースもある。それには表現意欲
や不安といった情動的な要因も影響していると考えられる(Rod, 2012)。筆者は表現の自由
度を増すことによって意欲を引き出せないかと考え、短いストーリーを創作する活動を取
り入れてみた。その実践活動について報告する .....published_or_final_versio
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Temporal Control of the TGF-β Signaling Network by Mouse ESC MicroRNA Targets of Different Affinities.
Although microRNAs (miRNAs) function in the control of embryonic stem cell (ESC) pluripotency, a systems-level understanding is still being developed. Through the analysis of progressive Argonaute (Ago)-miRNA depletion and rescue, including stable Ago knockout mouse ESCs, we uncover transforming growth factor beta (TGF-β) pathway activation as a direct and early response to ESC miRNA reduction. Mechanistically, we link the derepression of weaker miRNA targets, including TGF-β receptor 1 (Tgfbr1), to the sensitive TGF-β pathway activation. In contrast, stronger miRNA targets impart a more robust repression, which dampens concurrent transcriptional activation. We verify such dampened induction for TGF-β antagonist Lefty. We find that TGF-β pathway activation contributes to the G1 cell-cycle accumulation of miRNA-deficient ESCs. We propose that miRNA target affinity is a determinant of the temporal response to miRNA changes, which enables the coordination of gene network responses
NMR study of the Superconducting gap variation near the Mott transition in CsC
Former extensive studies of superconductivity in the \textit{A}C
compounds, where \textit{A} is an alkali, have led to consider that Bardeen
Cooper Schrieffer (BCS) electron-phonon pairing prevails in those compounds,
though the incidence of electronic Coulomb repulsion has been highly debated.
The discovery of two isomeric fulleride compounds CsC which
exhibit a transition with pressure from a Mott insulator (MI) to a
superconducting (SC) state clearly re-opens that question. Using pressure ()
as a single control parameter of the C balls lattice spacing, one can
now study the progressive evolution of the SC properties when the electronic
correlations are increased towards the critical pressure of the Mott
transition. We have used C and Cs NMR measurements on the cubic
phase A15-CsC just above kbar, where the SC
transition temperature displays a dome shape with decreasing cell
volume. From the dependence below of the nuclear spin lattice
relaxation rate we determine the electronic excitations in the
SC state, that is , the SC gap value. We find that
increases with decreasing towards , where decreases on the
SC dome, so that increases regularly upon approaching the
Mott transition. These results bring clear evidence that the increasing
correlations near the Mott transition are not significantly detrimental to SC.
They rather suggest that repulsive electron interactions might even reinforce
elecron-phonon SC, being then partly responsible for the large values,
as proposed by theoretical models taking the electronic correlations as a key
ingredient.Comment: 5 pages, 4 figures, Supplemental Materia
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