229 research outputs found

    Prison Visitation Policy and Procedure Guide

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    In this assignment you will use artificial intelligence (AI)—specifically ChatGPT—to create a visitation information guide for a prison. This assignment has multiple learning objectives: learning how to draft and refine official policies and procedures; exploring the utility of AI; and validating the accuracy of AI tools as they apply to criminal justice practices

    Using Video Prompting for Daily Living Skill Acquisition in Adults with Intellectual and Developmental Disabilities

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    The current study examined the effects of video prompting on the acquisition of a daily living skill with adults who have intellectual or developmental disabilities (IDD). A multiple baseline across participants design was used to assess whether a video prompting procedure was able to teach adults with IDD a daily living skill with minimal socially mediated instruction. It was found that performance increased once the intervention was applied. Future directions for research and application in teaching daily living skills to adults with IDD are discussed

    Cost effectiveness of treatments for wet age-related macular degeneration

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    Age-related macular degeneration (AMD) is a leading cause of blindness in people aged >= 50 years. Wet AMD in particular has a major impact on patient quality of life and imposes substantial burdens on healthcare systems. This systematic review examined the cost-effectiveness data for current therapeutic options for wet AMD. PubMed and EMBASE databases were searched for all articles reporting original cost-effectiveness analyses of wet AMD treatments. The Centre for Reviews and Dissemination and Cochrane Library databases were searched for all wet AMD health technology assessments (HTAs). Overall, 44 publications were evaluated in full and included in this review. A broad range of cost-effectiveness analyses were identified for the most commonly used therapies for wet AMD (pegaptanib, ranibizumab and photodynamic therapy [PDT] with verteporfin). Three studies evaluated the cost effectiveness of bevacizumab in wet AMD. A small number of analyses of other treatments, such as laser photocoagulation and antioxidant vitamins, were also found. Ranibizumab was consistently shown to be cost effective for wet AMD in comparison with all the approved wet AMD therapies (four of the five studies identified showed ranibizumab was cost effective vs usual care, PDT or pegaptanib); however, there was considerable variation in the methodology for cost-effectiveness modelling between studies. Findings from the HTAs supported those from the PubMed and EM BASE searches; of the seven HTAs that included ranibizumab, six (including HTAs for Australia, Canada and the UK) concluded that ranibizumab was cost effective for the treatment of wet AMD; most compared ranibizumab with PDT and/or pegaptanib. By contrast, HTAs at best generally recommended pegaptanib or PDT for restricted use in subsets of patients with wet AMD. In the literature analyses, pegaptanib was found to be cost effective versus usual/best supportive care (including PDT) or no treatment in one of five studies; the other four studies found pegaptanib was of borderline cost effectiveness depending on the stage of disease and time horizon. PDT was shown to be cost effective versus usual/best supportive care or no treatment in five of nine studies; two studies showed that PDT was of borderline cost effectiveness depending on baseline visual acuity, and two showed that PDT was not cost effective. We identified no robust studies that properly evaluated the cost effectiveness of bevacizumab in wet AMD

    Racial and Ethnic Health Disparities in Incarcerated Populations

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    Alarming disparities in population health and wellness in the United States have led to multi-disciplinary research efforts to create health equity. Identifying disparities, elucidating the etiological bases of disparities, and implementing solutions to eliminate disparities are part of the U.S. national health agenda. Racial and ethnic disparities have been identified throughout the cancer control continuum, in cardiovascular disease, diabetes and a multitude of other conditions. The causes of disparities are complex, condition specific, and conjectured to result from combinations of biological and socio-behavioral factors. Racial and ethnic health disparities within the vast incarcerated communities have been excluded from most studies, yet are of significant ethical and fiscal concern to inmates, governing bodies, and non-incarcerated communities into which inmates return. Importantly, research on racial and ethnic disparities in this unique population may shed light on the relative etiologies of health disparities and solutions for creating health equity throughout the general population in the United States

    Decision trees in epidemiological research

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    Background: In many studies, it is of interest to identify population subgroups that are relatively homogeneous with respect to an outcome. The nature of these subgroups can provide insight into effect mechanisms and suggest targets for tailored interventions. However, identifying relevant subgroups can be challenging with standard statistical methods. Main text: We review the literature on decision trees, a family of techniques for partitioning the population, on the basis of covariates, into distinct subgroups who share similar values of an outcome variable. We compare two decision tree methods, the popular Classification and Regression tree (CART) technique and the newer Conditional Inference tree (CTree) technique, assessing their performance in a simulation study and using data from the Box Lunch Study, a randomized controlled trial of a portion size intervention. Both CART and CTree identify homogeneous population subgroups and offer improved prediction accuracy relative to regression-based approaches when subgroups are truly present in the data. An important distinction between CART and CTree is that the latter uses a formal statistical hypothesis testing framework in building decision trees, which simplifies the process of identifying and interpreting the final tree model. We also introduce a novel way to visualize the subgroups defined by decision trees. Our novel graphical visualization provides a more scientifically meaningful characterization of the subgroups identified by decision trees. Conclusions: Decision trees are a useful tool for identifying homogeneous subgroups defined by combinations of individual characteristics. While all decision tree techniques generate subgroups, we advocate the use of the newer CTree technique due to its simplicity and ease of interpretation

    Dedicated switch-hitting, risking safety, embodied transcendence and other apparent contradictions.

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    My work reflects a long-standing attraction to the material and experiential imperfections that emerge through a collision of physical and cultural reality. My use of biological materials such as feathers in tandem with rigid systems exaggerates this contrast. It suggests the divide between a linguistic, conceptual space and an inherently organic and unpredictable physical space. While experiencing the work, the viewer is enveloped in a responsive environment of sound and that reveals the constantly shifting nature of their personal, physical experience of the environment. While embarking on what seems at first glance a practice that fits in with modernist ideals of truth and the progress of human knowledge, I do not seek to reinforce these ideals. Rather, I use humor to subvert modernist hierarchies of aesthetic value. The work borrows from a diverse range of sources such as Greek mythology, contemporary advertising, camp, cinema, art history, and representations of technological progress

    Cost-effectiveness of ranibizumab in treatment of diabetic macular oedema (DME) causing visual impairment : evidence from the RESTORE trial

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    Background/aims To evaluate the cost-effectiveness of ranibizumab as either monotherapy or combined with laser therapy, compared with laser monotherapy, in the treatment of diabetic macular oedema (DME) causing visual impairment from a UK healthcare payer perspective. Methods A Markov model simulated long-term outcomes and costs of treating DME in one eye (BCVA <= 5 letters) based on data from the RESTORE Phase III trial. Outcomes measured in quality-adjusted life-years (QALYs) were simulated for a 15-year time horizon based on 12-month follow-up from RESTORE and published long-term data. Costs included treatment, disease monitoring, visual impairment and blindness (at 2010 price levels). Results Ranibizumab monotherapy resulted in a 0.17 QALY gain at an incremental cost of 4191 pound relative to laser monotherapy, yielding an incremental cost-effectiveness ratio (ICER) of 24 pound 028. Probabilistic sensitivity analysis showed a 64% probability of being cost-effective at a threshold of 30 pound 000 per QALY. Combined ranibizumab and laser therapy resulted in a 0.13 QALY gain at an incremental cost of 4695 pound relative to laser monotherapy (ICER 36 pound 106; 42% probability of ICER <30 pound 000). Conclusions Based on RESTORE 1-year follow-up data, ranibizumab monotherapy appears to be cost-effective relative to laser monotherapy, the current standard of care. Cost-effectiveness of combination therapy is less certain. Ongoing studies will further inform on disease progression and the need for additional ranibizumab treatment

    Disproportionate School Disciplinary Responses: An Exploration of Prisonization and Minority Threat Hypothesis Among Black, Hispanic, and Native American Students

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    This research tests two potential explanations of school disciplinary responses: minority threat hypothesis and prisonization of schools. Data from the Arizona Safe and Drug-Free Schools (SDFS) survey and Arizona Youth Survey (AYS) are analyzed using ordinary least squares (OLS) regressions. Findings demonstrate that the percentage of Black, Hispanic, and Native American students was not associated with exclusionary responses to school misconduct, but was linked to decreases in mild and restorative disciplinary practices. Findings support the hypothesis that minority threat reduces access to mild and restorative disciplinary responses. Although, further research is needed on the roles of mental health professionals and counselors in school disciplinary procedures to better guide policy and school administrator expectations
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