22 research outputs found
The Pan-B Cell Marker CD22 Is Expressed on Gastrointestinal Eosinophils and Negatively Regulates Tissue Eosinophilia
IL-13 Induces Esophageal Remodeling and Gene Expression by an Eosinophil-Independent, IL-13Rα2–Inhibited Pathway
Paired Ig-like Receptor B Inhibits IL-13–Driven Eosinophil Accumulation and Activation in the Esophagus
Esophageal eosinophil level in an allergen-induced experimental eosinophil esophagitis model in miR-21<sup>+/+</sup> and miR-21<sup>−/−</sup> mice.
<p>Eosinophil levels in the esophagus were determined by morphometric analysis following anti-MBP staining. N = 5–6 mice per group. Data are represented as mean ± S.E.M. Data are representative of 2 independent experiments.</p
Levels of apoptosis in the eosinophil progenitor culture from the miR-21<sup>+/+</sup> and miR-21<sup>−/−</sup> mice.
<p>Levels of Annexin V and 7AAD staining during eosinophil differentiation culture as determined by FACS. The viable cells are AnnexinV<sup>−</sup> 7AAD<sup>−</sup>. The early apoptotic cells are AnnexinV<sup>+</sup> 7AAD<sup>−</sup>. The late apoptotic cells are AnnexinV<sup>+</sup> 7AAD<sup>+</sup>. Data are representative of 3 independent experiments.</p