1,912 research outputs found

    Nordic electricity congestion's arrangement as a model for Europe : physical constraints or operators' opportunism?

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    Congestion on power grids seems a physical reality, a "hard" fact easy to check. Our paper models a different idea: congestion signal may be distorted by transmission system operators (TSOs), which puts the European integrated electricity market at risk. 1Ê» when the TSOs share the revenue produced by congestion's pricing they have an incentive in distorting data. 2Ê» because congestion signals are not physical data but "home made" conventions, TSOs could be able distorting them. 3Ê» when congestion appears on cross border lines that link several countries with their own regulatory mechanisms, the settlement of this incentive's problem necessitates a high degree of coordination. Congestion puts undoubtedly the threat of a collapse on interconnected grids. The "capacity constrained situations" have therefore to be avoided. Congestion signalling depends on norms set by TSOs and a signal is given when the power flows attain the "secure" limits set by TSOs. These security norms are not stable and invariable because some flexibility is needed by the very nature of the power flows and because lines physical capacity limits are not constant. Therefore TSOs are defining the congestion signal on a variable, complex and non transparent constraint and may manipulate it for their own interests. In Nordic countries the "Light Handed Regulation" makes this opportunistic behaviour more likely. We need a more effective congestion regulatory mechanism.Supported by the MIT Center for Energy and Environmental Policy Research

    Simulations expérimentale et numérique de réfractaires verriers électrofondus riches en zircone

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    International audienceLes rĂ©fractaires Ă©lectrofondus Ă  TrĂšs Haute Teneur en Zircone sont utilisĂ©s dans la construction des fours verriers. Le fond de la zone fusion est constituĂ© de dalles de THTZ (88%vol ZrO2, 12%vol phase vitreuse), matĂ©riau choisi pour sa faible conductivitĂ© thermique, sa forte rĂ©fractaritĂ© et son inertie chimique. Le THTZ est Ă©laborĂ© par Ă©lectrofusion, coulĂ© dans des moules puis refroidi de maniĂšre contrĂŽlĂ©e jusqu'Ă  tempĂ©rature ambiante, domaine oĂč le matĂ©riau se caractĂ©rise par un comportement fragile. Lors de la premiĂšre mise en chauffe du four ("attrempage"), des contraintes internes d'origine thermique sont gĂ©nĂ©rĂ©es au sein des dalles. L'objectif de l'Ă©tude est alors d'estimer ce champ de contraintes. L'Ă©tude a tout d'abord consistĂ© Ă  simuler expĂ©rimentalement la chauffe d'une dalle de THTZ dans un four verrier pendant l'attrempage. Pour ce faire, nous avons dĂ©veloppĂ© et utilisĂ© un dispositif expĂ©rimental consistant Ă  poser une dalle de THTZ instrumentĂ©e en thermocouples sur une plaque chauffĂ©e Ă  une vitesse contrĂŽlĂ©e. Les donnĂ©es thermiques ainsi obtenues ont permis, via un calcul numĂ©rique thermique (code de calcul ZĂ©BuLoN, Centre des MatĂ©riaux), de dĂ©terminer les coefficients d'Ă©change aux interfaces dalle/air et dalle/plaque chauffante. Puis, Ă  partir de cela, un calcul numĂ©rique mĂ©canique nous a permis de dĂ©terminer les contraintes gĂ©nĂ©rĂ©es par l'attrempage dans la dalle

    Transgenesis and humanization of murine antibodies.

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    International audienceThe properties of monoclonal antibodies explain why they are such a successful class of therapeutic molecules. However, pionneered initial antibodies were of murine origin and triggered an immune response which limited the therapeutic potential of the antibody and generated deleterious effects. Consequently, tremendous efforts have been developped to engineer these murine Ig by introducing human sequences in vitro, or in vivo by humanization of murine antibodies, leading to chimeric immunoglobulins, and more recently generation of fully human antibodies in transgenic mice with a more or less diversified V repertoire. These approaches have led to the development of an increasing number of these chimeric or humanized monoclonal antibodies entering pharmaceutical pipelines. double dagger

    Arcing on Solar Generators by Collection of Ionospheric Plasma Currents

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    International audienceThere are several well-known possibilities to trigger a secondary arc on solar arrays by creation of conductive plasma produced in the gap between two solar cell strings. It could be by electrostatic discharges due to an inverse potential gradient condition, micrometeoroid impacts or laser impacts. The development of electrical propulsion for satellites requires higher voltages on solar arrays. These voltages strongly modify the plasma-satellite interactions, especially by increasing the collection of plasma currents. By studying this plasma collection current on solar cell samples, we have detected secondary arcs between two strings without any triggering event as previously described. Focusing on this event, we found that a series of physical phenomena may lead to secondary arcing situation: heating by plasma current collection, outgassing, Paschen discharge conditions and then secondary arcing. We have reproduced on solar cell like samples what occurs when an arc starts and the conditions for its occurrence. Thereby, we have defined when this phenomenon is able to happen on real solar arrays

    Myrtilles et mĂ©moire : les myrtilles protĂšgent-elles des pertes de mĂ©moire liĂ©es Ă  l’ñge ? Etude bibliographique

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    Cette Ă©tude bibliographique dĂ©crit briĂšvement les fonctions cognitives ainsi que les diffĂ©rents types de mĂ©moire. Puis elle expose les effets du vieillissement et des aliments sur les mĂ©moires. Enfin, les travaux sur les effets des myrtilles sur la mĂ©moire, ainsi que leurs mĂ©canismes molĂ©culaires sont regroupĂ©s et analysĂ©s, chez les rongeurs et chez l’homme. Cette synthĂšse montre que certains aliments, les myrtilles notamment, ont des effets nets sur la mĂ©moire spatiale des vieux rats. La poursuite des Ă©tudes expĂ©rimentales est nĂ©cessaire car les pertes de mĂ©moires liĂ©es Ă  l’ñge sont un flĂ©au pour la population vieillissante. Il serait donc opportun de valider ces Ă©tudes par un essai clinique randomisĂ© de grande ampleur de l’effet des myrtilles sur la mĂ©moire des personnes ĂągĂ©es

    Selection on the wing in Heliconius butterflies

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    <p>Asbtract</p> <p>To what extent population structure favours the establishment of new phenotypes within a species remains a fundamental question in evolutionary studies. By reducing gene flow, habitat fragmentation is a major factor shaping the genetic structuring of populations, favouring isolation of small populations in which drift may rapidly change frequencies of new variants. When these variants provide advantages to individuals, the combined effect of selection and drift can lead to rapid shifts in phenotypes. In a study published in <it>BMC Genetics</it>, Albuquerque de Moura <it>et al. </it>asked whether such a general pattern of population structure can be observed in <it>Heliconius </it>species, which could have strong implication in the evolution of colour pattern diversification in these butterflies. In this commentary we discuss the potential roles of these three processes (drift, selection and dispersal) on the evolution of <it>Heliconius </it>wing patterns in regard to the findings of a common fine-scale population structure within the co-mimetic species <it>H. melpomene </it>and <it>H. erato</it>. Indeed, a general pattern of population subdivision in the history of these two species may have provoked the major phenotypical shifts observed in their wing colour patterns. The suggestion that coupled environmental pressures (counter-selection of dispersal and selection on co-evolved traits) could be responsible for identical genetic differentiation profiles in <it>H. erato </it>and <it>H. melpomene </it>clearly merits further investigations using both detailed population genetic (including landscape genetic) and ecological studies.</p
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