9 research outputs found
Additional file 7: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S5. Ingenuity Pathway Analysis depicts PTEN signaling pathways based on microarray data and available literatures (TIF 1204 kb
Additional file 5: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Table S2. The top ten significantly changed Canonical Pathway based on microarray analysis. (DOC 41 kb
Additional file 2: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S1. Upper: The fluorescence microscopy detects the transfection efficiency of each shRNA (KD1, KD2 and KD3). Lower: qRT-PCR assay demonstrates the mRNA level of RAP1A gene is lowest in SW620 cells transfected with KD3 shRNA. (TIF 19639 kb
Additional file 3: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S2. RAP1A overexpression promotes the growth of DLD-1 CRC cells in vitro. a: RAP1A expression is higher in overexpression (OE) group than that in negative control (NC) group. b: the relative 490Â nm absorbance of OE group increases more quickly than that of NC group within five days. c: RAP1A overexpression has no significant impact on the phase fraction in DLD-1 cells. d: the apoptosis rates of OE group are lower than that of NC group. e: the clone numbers of OE group are more than that of NC group. (TIF 4391 kb
Additional file 6: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S4. Ingenuity Pathway Analysis depicts IL-8 signaling pathways based on microarray data and available literatures (TIF 515 kb
Additional file 4: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S3. Z-scores of top ten canonical pathways (TIF 322 kb
Additional file 8: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S6. Z-scores of top ten enriched diseases and functions (TIF 305 kb
Additional file 9: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Figure S7. qRT-PCR detects the expression of 27 significantly expressed genes in SW620 cells after RAP1A knockdown. (TIF 3186 kb
Additional file 1: of High expression of Ras-related protein 1A promotes an aggressive phenotype in colorectal cancer via PTEN/FOXO3/CCND1 pathway
Table S1. Primer sequences for the quantitative polymerase chain reaction. (DOC 76 kb