Lesions mimicking lacrimal gland pleomorphic adenoma

Aim: To report a series of patients with lacrimal gland lesions simulating the clinicoradiological features of lacrimal gland pleomorphic adenoma (LGPA). Methods: Multicentre retrospective, interventional case series. Clinical records of all patients with lesions mimicking LGPA seen in five orbital units were reviewed. Results: The study included 14 patients (seven men and seven women) with a mean age of 50.9 years. The diagnosis of LGPA was made in all cases by experienced orbital surgeons, based on clinicoradiological features, and lacrimal gland excision was performed. Postoperative histology revealed lymphoma (four patients), chronic dacryoadenitis (three patients), adenoid cystic carcinoma (two patients), Sjogren's syndrome (two patients), cavernous haemangioma (one patient), benign lymphoid hyperplasia (one patient) and granulomatous dacryoadenitis (one patient). Comparison with the total number of histologically confirmed LGPA cases seen during the study period revealed that 22.6% of cases of suspected LGPA were misdiagnosed based on clinicoradiological criteria. Conclusions: Many different lesions may mimic the clinicoradiological features of LGPA. The accepted clinicoradiological criteria used for the diagnosis of LGPA have a high false-positive rate, even in experienced hands. Based on this study, the authors believe that fine-needle aspiration biopsy or intraoperative biopsy and frozen section diagnosis may help reduce unnecessary lacrimal gland excision.Venkatesh C Prabhakaran, Paul S Cannon, Alan McNab, Garry Davis, Brett O’Donnell, Peter J Dolman, Raf Ghabrial, Dinesh Selv

Social Networking Websites and Posting Personal Information: An Evaluation of Protection Motivation Theory

The popularity of social networking websites among Internet users continues to grow, even though social networking remains a risk for users who do not participate with caution. Using protection motivation theory (PMT) as a theoretical lens to provide a research model, and by issuing a fear appeal to social network users about the potential threat to their privacy, this study identified perceptions and beliefs held by users that influence their behavioral responses to the imposed threats. A snowball sample survey measuring the variables conceptualized by PMT was completed by 522 social network users. A time-ordered hierarchical regression analysis of the responses showed that PMT provides explanations for both adaptive and maladaptive responses, particularly for the response of hopelessness. Implications and directions for future research in this area are offered

Forward and Inverse Processing in Electromagnetic NDE Using Squid

Electromagnetic NDE has been successfully applied to the detection of surface cracks and is routinely used to locate flaws in airframes, pipelines and in steel offshore oil platforms. However, there are still many problems to be solved, particularly in the aviation industry, which require the detection of deeper flaws such as corrosion in multi-layered structures and cracks around rivet holes which are obscured by the head of the rivet. Most systems use coils as detectors (though Hall probes are occasionally used), which have low sensitivity at low frequencies due to the fact that the induced voltage is proportional to the rate of change of magnetic flux through the coil. Unfortunately it is necessary to use low frequencies to detect deep subsurface flaws on account of the skin-depth effect, otherwise the electromagnetic field cannot propagate down to the depth of the flaw. SQUID (Superconducting Quantum Interference Device) sensors are ideally suited to overcome the deficiencies of coils, because they are primarily detectors of magnetic flux which, together with their high sensitivity, makes the detection of deep flaws more likely. SQUIDs have been successfully used for measuring very low magnetic fields, particularly in the field of biomagnetism, and it is hoped to exploit this sensitivity to detect flaws at large stand-off distances for example in pipelines which are surrounded by thick layers of cladding

Using simplified models to communicate the importance of prevention, detection and preparedness before a disease outbreak

Summary Frontline farm workers and veterinary-policy-makers are arguably in the best positions to influence prevention, detection, and preparedness-for-control of farm animal diseases. It is important that such individuals make biologically sound decisions concerning the daily management and regulation of the health of animals. Such decisions should be based on a good understanding of key principles of disease spread and control. This paper summarises these principles, as described in previous publications, into simple models. These models may be used to communicate concepts to readers who may not have time to study more complex models. These models illustrate the relationship between the development of new disease cases (from existing cases, i.e. the reproductive ratio R) and (i) the duration of the period during which existing cases are available as infectious, (ii) contact rates, (iii) transmission rates and (iv) susceptibility. Understanding these concepts through models has great utility, facilitating better decisions for disease prevention, detection and preparedness-for-control, before an outbreak becomes unmanageable. These basic concepts apply to all animal species, including humans

The Allometry of Daily Energy Expenditure in Hummingbirds: An Energy Budget Approach

1. Within-clade allometric relationships represent standard laws of scaling between energy and size, and their outliers provide new avenues for physiological and ecological research. According to the metabolic-level boundaries hypothesis, metabolic rates as a function of mass are expected to scale closer to 0.67 when driven by surface-related processes (e.g. heat or water flux), while volume-related processes (e.g. activity) generate slopes closer to one. 2. In birds, daily energy expenditure (DEE) scales with body mass (M) in the relationship log (DEE)=2.35+0.68×log (M), consistent with surface-level processes driving the relationship. However, taxon-specific patterns differ from the scaling slope of all birds. 3. Hummingbirds have the highest mass-specific metabolic rates among all vertebrates. Previous studies on a few hummingbird species, without accounting for the phylogeny, estimated that the DEE–body mass relationship for hummingbirds was log (DEE)=1.72+1.21×log (M). In Contrast to the theoretical expectations, this slope \u3e1 indicates that larger hummingbirds are less metabolically efficient than smaller hummingbirds. 4. We collected DEE and mass data for 12 hummingbird species, which, combined with published data, represented 17 hummingbird species in eight of nine hummingbird clades over a sixfold size range of body size (2.7–17.5 g). 5. After accounting for phylogenetic relatedness, we found DEE scales with body mass as log(DEE)=2.04+0.95×log (M). This slope of 0.95 is lower than previously estimated for hummingbirds, but much higher than the slope for all birds (0.68). The high slopes of torpor, hovering and flight potentially explain the high interspecific DEE slope for hummingbirds compared to other endotherms

Mechanistic Insights into the Desorption of Methanol and Dimethyl Ether Over ZSM-5 Catalysts

Acknowledgements Financial support from the Petroleum Technology Development Fund of Nigeria (PTDF/ED/PHD/OO/766/15) and from the European Commission in the scope of the 7th Framework program BIOGO project (Grant Number: 604296) https://www.biogo. eu/ is acknowledged.Peer reviewedPublisher PD

The State of the Region: Hampton Roads 2016

This is Old Dominion University\u27s 17th annual State of the Region report. While it represents the work of many people connected in various ways to the university, the report does not constitute an official viewpoint of Old Dominion or it\u27s president, John R. Broderick. The report maintains the goal of stimulating thought and discussion that ultimately will make Hampton Roads an even better place to live. We are proud of our region\u27s many successes, but realize that it is possible to improve our performance. In order to do so, we must have accurate information about where we are and a sound understanding of the policy options open to us.https://digitalcommons.odu.edu/economics_books/1002/thumbnail.jp