Additional file 5: Figure S2. of DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease

Validation of the bisulfite modification and pyrosequencing assays for relevant loci in HDAC4, HOXA2 and PPP1R18 genes. Plots comparing 0, 25, 50, 75 and 100 % of methylated DNA with obtained methylation results are shown; only assays with an acceptable performance (r 2 values over 0.95) were used in this study. (TIF 149 kb

Additional file 2: Table S1. of DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease

Summary of differentially methylated regions. (DOCX 16 kb

Additional file 7: Table S4. of DNA methylation profiling identifies novel markers of progression in hepatitis B-related chronic liver disease

Demographic, clinical and laboratory characteristics of the non-progressors and progressors in serial biopsies. (DOCX 18 kb