Biogenetically Inspired Total Syntheses of <i>Lycopodium</i> Alkaloids, (+)-Flabellidine and (−)-Lycodine

The first asymmetric total synthesis of (+)-flabellidine (<b>2</b>) and the shortest total synthesis of (−)-lycodine (<b>3</b>) were accomplished by a strategy featuring the one-pot construction of a tetracyclic lycodine skeleton from a linear precursor, which was inspired by the biosynthetic consideration of <i>Lycopodium</i> alkaloids

Additional file 2: Figure S2. of Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis

Quantification of the fluorescence intensity in Fig. 1C. **p < 0.01 (n = 4). (TIFF 897 kb

Additional file 4: Figure S4. of Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis

Bands of Western blot analysis for the cropped images in Fig. 3a (A), 3b (B) and 3c (C) are provided in this file. (TIFF 5449 kb

Additional file 3: Figure S3. of Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis

Bands of Western blot analysis for the cropped images in Fig. 2c are provided in this file. (TIFF 1856 kb

Additional file 1: Figure S1. of Low-intensity pulsed ultrasound rescues insufficient salivary secretion in autoimmune sialadenitis

Schematic representation of the in vitro LIPUS system used. A cell culture plate with medium was placed in the ultrasound field at a distance of about 1 mm from the transducer to optimize beam uniformity across the target region. (TIFF 1093 kb