The Effects of Low Power Lasers in Healing of Oral Ulcers

It is the output power and density of the lasers which determine whether a laser is a low or high-power one. If the density is less than 670mW/cm2, the laser is called a low power one. The output power of these lasers is usually less than 250mW. They use different mechanisms to accelerate wound healing such as: cellular biostimulation, improvement of circulation, vasodilation, analgesic and anti-inflammatory effects. They don’t contribute to any drug resistance, therefore, several studies have been conducted on the application of these lasers for the curing of acute, chronic and recurrent ulcers such as mucositis, aphthous ulcers, herpetic lesions and lichen planus. In this article we will survey the effects of low-power lasers in the healing of oral ulcers

The comparison of insulin resistance frequency in patients with recurrent early pregnancy loss to normal individuals

<p>Abstract</p> <p>Background</p> <p>Patients with ≥ 3 recurrent spontaneous miscarriages are classified as having RSM. Polycystic ovary syndrome (PCOS) is associated with insulin resistance (IR). The purpose of this study is to evaluate the association of IR and RMS.</p> <p>Methods</p> <p>Present case- control prospective study was performed on 100 women in control group (with a history of at a live birth and no history of one more abortion) and study group (with a history of ≥ 3 RMS) who were not diabetes and PCOS. Two groups matched in base of age and body mass index. Blood was withdrawn from the case and control patients for the determination of the fasting blood glucose (FG), fasting insulin (FI) levels and ultrasonography was performed on all the patients.</p> <p>Results</p> <p>The observed differences between age, FG and FG to FI ratio levels in case and control groups were not significant (<it>p </it>> 0.05) but it was significant about fasting insulin (<it>p </it>= 0.0119). FI of < 20 <it>μu/ml </it>or ≥ 20 <it>μu/ml </it>in case and control group was significant (Chi-square: 4.083, p: 0.0433, odds ratio: 4.4386, CI95% = 1.1541 to 17.0701), whereas the difference between absolute and proportional frequency of patients with FG to FI ratio of < 4.5 and ≥ 4.5 in case and control groups was not significant (Chi-square: 2.374, <it>p </it>= 0.123).</p> <p>Conclusion</p> <p>Current study showed that in women with RPL, in Iranian race like Americans, frequency of insulin resistance in high, therefore there is a probability of the degree of insulin resistance in women with RPL.</p

Acute and critical care for rabies bitten patients and the different outcomes in a Family: A Post Exposure Prophylaxis (PEP) Failure report

Rabies is a zoonotic viral disease that spread via infected animal saliva. Rabies virus belongs to Lyssavirus genus (Rhabdoviridae family) and the disease is endemic in Iran. The disease causes a fatal encephalomyelitis by infecting the nervous system. Dogs are the most common source of human rabies cases. In this presentation, we had a 58-year-old man who had a dog bitten history on his face and hands with his other two family members with the same dog at the same time. They received post-exposure prophylaxis (PEP) as soon as possible (from day 0). Eighteen days after bitten the man hospitalized and died of rabies three days after hospitalization. Other two relatives were healthy without any rabies symptom. The man was an Iranian veteran with residual body insults during the attacks of chemical warfare from the combat front. Obtained data in this study suggested that the direct inoculation of the virus to the nerve and immune system inability in virus clearing system were possible etiologies of PEP failure in the reported case. Keywords: Rabies Virus, Immunoglobulin, Pre-Exposure Prophylaxis (PrEP), Immunosuppressio

Association of Lifestyle and Aphthous Stomatitis Among Dentistry Students

Background: Recurrent aphthous stomatitis (RAS) is the most common ulcerative oral lesions. Many factors including genetics, stress, lifestyle, gastric diseases and nutritional habits play a major role in the etiology of recurrent aphthous ulcers. The aim of this study was to evaluate the lifestyle of patients with a history of aphthous stomatitis. Methods: This cross-sectional study was conducted on 99 dentistry students with a history of aphthous stomatitis. The control group consisted of 145 dentistry students without any history of the lesion. Demographic information and lifestyle factors including smoking, body mass index, place of living, marital status, regular exercise were recorded. Nutritional habits were evaluated using a modified Food Frequency Questionnaire containing 95 food variables. Independent t-test and Mann Whitney test were used to compare the two groups. Linear regression analysis were used to determine the predictors. Results: There was no significant difference in nutritional habits of study participants. A family history of RAS was more frequently noticed in the case group (43.1%) rather than control group (27.7). Multivariate logistic regression model showed that the most powerful predictors of aphthous lesions were familial history of lesions (OR = 2.4, 95%CI: 1.11-5.13) and food allergy (OR = 4.71, 95%CI: 2.70 to 8.22) respectively. Conclusion: Based on the results of the present study, life style and diet are not associated with aphthous lesions. Considering that aphthous stomatitis is a multifactorial disease, there is a need to study other risk factors and laboratory tests

In Vitro Comparison of Biological Effects of Coe-Pak and Reso-Pac Periodontal Dressings

Objectives: The purpose of the present study was to compare the cytotoxicity of Reso-Pac and Coe-Pak periodontal dressing. Material and Methods: According to ISO-10993-12:2012, 1-, 3- and 7-day extracts of the two periodontal dressings were prepared in cell culture medium and exposed to the two cultured cell lines. Cell viability and proliferation at 24 h and 72 h following exposure were evaluated using quantitative MTT assay. Results: The results showed a significant (P 0.05) difference was found in the viability of cells exposed to undiluted (100%) one-day extract and diluted (50%) extract of both understudy materials at 24 h and 72 h after exposure. Conclusions: Based on the results, Reso-Pac periodontal dressing has less cytotoxicity than Coe-Pak

Evaluation of oxidative stress in endometriosis:A case-control study

Abstract Background: Recent studies have suggested that oxidative stress (OS) may have a contribution in the pathogenesis of endometriosis. However, the results of previous studies regarding OS in endometriosis are controversial. The objective of this study was to compare the serum levels of OS markers in endometriosis versus the control group. Methods: This case-control study was carried out on 30 women with endometriosis aged 20-38 from March 2011 to November 2013. These patients were admitted in Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol, Iran. The serum samples of 40 women with same age were collected as the control group. The serum levels of malondialdehyde (MDA), carbonyl and iron were measured by photometric methods and compared between the patient and control groups using t-test. Also, we used ROC curve analysis to determine the discrimination ability of these markers. Results: Serum iron in endometriosis patients was significantly higher than control (p<0.0001). Area under ROC curve (AUC) for iron, MDA and carbonyl were 0.899, 0.648 and 0.530, respectively. Serum iron at cutoff value of 173.3 µg/dl exhibited high discrimination ability to recognize endometriosis from control. Conclusion: These findings indicate that the high level of serum iron may promote OS in patients with endometriosis. Also based on the ROC curve results, iron showed high discrimination ability to distinguish the patients with endometriosis from healthy subject

Exploring the effect of adding low dose human chorionic gonadotropin on oocyte maturation in women undergoing intracytoplasmic sperm injection: A randomized control trial

Background: The aim of this study was to examine the effect of adding low dose human chorionic gonadotropin (hCG) on oocyte maturity and hyper-stimulation syndrome in women undergoing Intra-cytoplasmic Sperm Injection (ICSI). Methods: In a randomaized clinical trail, 150 eligible patients undergoing a long GnRH agonist protocol were randomly divided into three groups of 50 women. The women in the first group received recombinant FSH alone (rFSH). The women in the second group received rFSH by 100 IU hCG daily. All participants in the three groups received rFSH by 200 IU hCG daily. The mean numbers of mature oocytes retrieved (MII oocytes) for normal responders as the primary outcome, and the occurrence ovarian hyperstimulation syndrome (OHSS) as the secondary outcome were measured for each group. A P-value of less than 0.05 was considered as statistically significant. Results: There was no significant difference in the comparison of the incidence of mature oocytes formation among the three groups. The number of OHSS was significantly lower in third group compared with those of the other groups (6% vs 14% and 18%, respectively; P = 0.03). Conclusion: The addition of 200 hCG to recFSH throughout the stimulation in a long GnRH agonist protocol only benefited a lower number of OHSS

Phytomodulatory effects of silver nanoparticles on Corchorus olitorius: Its antiphytopathogenic and hepatoprotective potentials

This study has reported the effects of biogenic silver nanoparticles (AgNPs) using cocoa pod extract on physiological tolerance indices, antioxidant activity and hepatoprotective potentials of Corchorus olitorius as well as its efficiency for controlling soil phytopathogens. C. olitorius seeds were grown in soil prepared with water (control), 0.05, 0.1, 0.15 and 0.2 mg AgNPs/g soil. C. olitorus grown with AgNPs had significantly (p < 0.05) higher free radical scavenging ability, ferric reducing ability, percentage germination, vigour indices, longer roots and shoots as well as lower moisture content over control. C. olitorius grown with AgNPs attenuated hydrogen peroxide (H 2 O 2 )-mediated reduction in catalase concentrations and H 2 O 2 -induced malondialdehyde elevations in liver. Efficiency of AgNPs to reduce soil phytopathogens (fungi and nematodes) revealed significant (p < 0.05) reduction in the incidences of soil and shoot Meloidogyne spp., Aspergillus terreus, A. niger, Fusarium spp. and Cladosporium spp. with increase in concentrations of AgNPs. More efficiently, there was complete extermination of A. niger and Fusarium spp. in the leaves of C. olitorius grown with AgNPs. Results in this study have shown the positive influence of AgNPs on C. olitorius by strengthening its resistance against fungi, and nematodes, improvement of its shelf-life, modulation of antioxidant activities and promotion of liver-detoxifying potentials.Fil: Azeez, Luqmon. Osun State University; NigeriaFil: Lateef, Agbaje. Ladoke Akintola University Of Technology; NigeriaFil: Wahab, Abideen A.. Osun State University; NigeriaFil: Rufai, Muhammed A.. Osun State University; NigeriaFil: Salau, Amadu K.. Fountain University; NigeriaFil: Ajayi, Ebenezer Idowu O. Osun State University; Nigeria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Ajayi, Mercy. Osun State University; NigeriaFil: Adegbite, Maryam K.. Osun State University; NigeriaFil: Adebisi, Basirat. Osun State University; Nigeri